Effect of Salicylate and Disodium Ethylenediaminetetraacetic Acid on the Rat Intestinal Absorption of Cefmetazole
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概要
- 論文の詳細を見る
The enhancement by disodium ethylenediaminetetraacetic acid (EDTA) of cefmetazole absorption from rat jejunum and colon was dependent on the pH of the administered solution. The higher the pH of the administered solution, the greater the effect of EDTA. However, the enhancement by salicylate of the cefmetazole absorption was dependent on salicylate absorption rather than on the pH of the administered solution. The effectiveness of EDTA was similar at the colon and at the jejunum, while salicylate showed a significantly greater effect at the colon than at the jejunum.
- 公益社団法人日本薬学会の論文
- 1985-10-25
著者
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鎌田 皎
Faculty Of Pharmaceutical Sciences Osaka University
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山崎 勝
Faculty of Pharmaceutical Sciences, Osaka University
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山崎 勝
大阪大学薬学部
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西畑 利明
大阪大学薬学部
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鈴鹿 卓美
Faculty of Pharmaceutical Sciences, Osaka University
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西畑 利明
Pharmacy Research Upjohn Tsukuba Research Laboratories
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西畑 利明
Faculty of Pharmaceutical Sciences, Osaka University
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鈴鹿 卓美
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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