ピリドキシン脂肪酸エステルの薬剤学的研究 : (III)Pyridoxine 5-octanoateの合成および物理化学的性質
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概要
- 論文の詳細を見る
Pyridoxine 5-octanoate was synthesized and its chemical and physical properties were studied. Molar extinction coefficient of its ethanol solution at 286.5mμ was 6.5 × 10^3 cm^<-1>mole^<-1>. It was soluble in various organic solvents such as benzene, chloroform, and ethanol, but its solubility in water was 0.273μmole/ml. Its solvent affinity was intermediate between pyridoxine and pyridoxine 3,4-dioctanoate. Pyridoxine 5-octanoate and pyridoxine 5-benzoate showed a weak vitamin B_6 activity for Saccharomyces carlsbergensis. Pyridoxine 5-octanoate was hydrolyzed completely in 0.055N H_2SO_4 at 126.5℃ for one hour.
- 日本ビタミン学会の論文
- 1968-08-25
著者
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青木 大
Faculty Of Pharmaceutical Sciences Osaka University
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鎌田 皎
Faculty Of Pharmaceutical Sciences Osaka University
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水野 亘恭
大阪大学薬学部薬剤学教室
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青木 大
大阪大学薬学部薬剤学教室
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鎌田 皎
大阪大学薬学部薬剤学教室
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水野 亘恭
武庫川女子大学薬学部
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水野 亘恭
武庫川女子大・薬
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