Screening of Bacteriophages Producing Endo-N-Acetylneuraminidase
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概要
- 論文の詳細を見る
Seven different bacteriophages were isolated from sewage with Escherichia coli K1 strains as host bacteria. These phages showed specific degrading activity for the host capsular polysacchardie, α2,8-linked polysialic acid. The bacteriophage-associated endo-N-acetylneuraminidases degraded only a homopolymer of α2,8-linked sialic acid and were not able to degrade other sialylated carbohydrates such as sialyl lactose. With respect to the minimum substrate size, each enzyme had its own specificty. Among the seven phages isolated, three enzymes exhibited novel endo-N-acetylneuraminidase activity in that they produced sialyl dimer as a main product and two of them degraded sialyl trimer or tetramer.
- 社団法人日本生物工学会の論文
- 1997-07-25
著者
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MACHIDA Yuichi
Department of Urology, Osaka City University Medical School
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Kawase Masaya
Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Kawase Masaya
Nagahama Institute of Bio-science and Technology
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Kawase M
Osaka Univ. Osaka Jpn
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Machida Yuichi
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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WATANABE Masaki
Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Osaka University
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IIJIMA SHINJI
Department of Chemical Engineering, Faculty of Engineering, Nagoya University
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Kawase Masaya
Laboratory Of Industrial Biochemistry Department Of Industrial Chemistry Faculty Of Engineering Kyot
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Kawase Masaya
Department Of Bioscience Nagahama Institute Of Bio-science And Technology
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Watanabe M
Foods And Liquors Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
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Iijima Shinji
Department Of Biotechnology School Of Engineering Naogya University
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Iijima Shinji
Department Of Biotechnology Faculty Of Engineering Nagoya University
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Kawase Mitsuo
Ngk Insulators Ltd.
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Miyake Katsuhide
Department of Biotechnology, School of Engineering, Nagoya University
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Kawase M
Research And Development Center Kobayashi Pharmaceutical Co. Ltd.
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Watanabe M
Graduate School Of Engineering Hiroshima Kokusai Gakuin University
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MURAKI TSUTOMU
Department of Biotechnology, Graduate School of Engineering, Nagoya University
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HATTORI KOUJI
Department of Biotechnology, Graduate School of Engineering, Naogoya University
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YOSHIDA YASUKO
NGK Insulators Ltd.,
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Hattori Kouji
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Muraki Tsutomu
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Miyake K
Nagoya University
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Miyake Katsuhide
Department Of Biotechnology School Of Engineering Nagoya University
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Yoshida Yasuko
Ngk Insulators Ltd.
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Watanabe Masaki
Department Of Applied Chemistry Graduate School Of Science And Engineering Ehime University
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Miyake Katsuhide
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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IIJIMA Shinji
Department of Agricultural Chemistry, The University of Tokyo
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