Novel Transdermal Drug Delivery System with Polyhydroxyalkanoate and Starburst Polyamidoamine Dendrimer
スポンサーリンク
概要
- 論文の詳細を見る
In search of an efficient transdermal drug delivery system (TDDS), a polyhydroxyalkanoate (PHA)-based system with a polyamidoamine dendrimer was examined. Tamsulosin was used as the model drug. The dendrimer was found to act as the weak enhancer. By adding the dendrimer, the dendrimer-containing PHA matrix achieved the clinically required amount of tamsulosin permeating through the skin model. This is also the first report of the application of PHA and dendrimer to the TDDS.
- 社団法人日本生物工学会の論文
- 2003-05-25
著者
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Kawase Masaya
Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Kawase Masaya
Nagahama Institute of Bio-science and Technology
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Yagi Kiyohito
Graduate School of Pharmaceutical Sciences, Osaka University
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Yagi K
Graduate School Of Pharmaceutical Sciences Osaka University
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Yagi Kiyohito
Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Yagi K
Osaka Univ. Osaka Jpn
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Kawase M
Nagahama Institute Of Bio-science And Technology
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Kawase M
Osaka Univ. Osaka Jpn
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Hayashi Yuka
Graduate School Of Pharmaceutical Sciences Osaka University
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Kawase Masaya
Laboratory Of Industrial Biochemistry Department Of Industrial Chemistry Faculty Of Engineering Kyot
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Kawase Masaya
Department Of Bioscience Nagahama Institute Of Bio-science And Technology
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Yagi Kiyohito
Department Of Biocehmical Engineering Faculty Of Pharmaceutical Sciences Osaka University
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YAMAKAWA Junji
Department of Earth Sciences, Graduate School of Natural Science and Technology, Okayama University
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Yamakawa Junji
Faculty Of Science Okayama University
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Yamakawa Junji
Department Of Earth Sciences Faculty Of Sciences Okayama University
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Kawase Mitsuo
Ngk Insulators Ltd.
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Kawase M
Research And Development Center Kobayashi Pharmaceutical Co. Ltd.
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MAEDA ISAMU
Graduate School of Pharmaceutical Sciences, Osaka University
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ITOH YOSHIAKI
Nitto Denko Co.
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HOSAKA YOSHIFUMI
Nitto Denko Co.
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KOBAYASHI ICHIRO
Nitto Denko Co.
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NAKANO YOSHIHISA
Nitto Denko Co.
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UMEDA FUSAKO
Graduate School of Pharmaceutical Sciences, Osaka University
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WANG ZHIOXIONG
Graduate School of Pharmaceutical Sciences, Osaka University
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Maeda Isamu
Laboratory Of Bio-functional Molecular Chemistry Graduate School Of Pharmaceutical Sciences Osaka Un
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Maeda Isamu
Graduate School Of Pharmaceutical Sciences Osaka University
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Umeda Fusako
Graduate School Of Pharmaceutical Sciences Osaka University
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Wang Zhioxiong
Graduate School Of Pharmaceutical Sciences Osaka University
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Nakano Y
Nitto Denko Co.
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Hosaka Yoshifumi
Graduate School Of Pharmaceutical Sciences Osaka University
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Itoh Y
Nitto Denko Co.
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Maeda Isamu
Graduate School of Agricultural Science, Utsunomiya University
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