Cytotoxic and Apoptosis-Inducing ent-Kaurane-Type Diterpenoids from the Japanese Liverwort Jungermannia truncata NEES

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概要

• 論文の詳細を見る

• Five new ent-kaurane-type diterpenoids and a new gymnomitrane (=barbatane)-type sesquiterpenoid have been isolated from the Japanese liverwort Jungermannia truncata NEES, together with twelve previously known ent-kaurane-type diterpenoids. The structures of the new compounds were elucidated by two-dimensional (2D) NMR experiments and chemical reaction. Some of the isolated compounds showed cytotoxicity against human leukemia cell lines and induced apoptosis.

• 公益社団法人日本薬学会の論文
• 2002-06-01

著者

• Sato Masao

  Faculty of Pharmaceutical Science, Tokushima Bunri University

• Nishiyama Atsuko

  Faculty Of Pharmaceutical Sciences Meijo University

• 近藤 昌夫

  Graduate School Of Pharmaceutical Sciences Osaka University:department Of Pharmaceutics And Biopharm

• 近藤 昌夫

  Graduate School Of Pharmaceutical Sciences Osaka Univ.

• ASAKAWA Yoshinori

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• Asakawa Y

  Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ.

• Kawase M

  Research And Development Center Kobayashi Pharmaceutical Co. Ltd.

• KONDOH Masuo

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• NAGASHIMA Fumihiro

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• UEMATSU Toshinari

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• NISHIYAMA Akiko

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• SAITO Sayaka

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• Saito Sayaka

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Kondoh Masuo

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Asakawa Y

  Tokushima Bunri Univ. Tokushima Jpn

• Asakawa Yoshinori

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Nishiyama A

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Uematsu T

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Nagashima F

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Nagashima Fumihiro

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Sato Masao

  Faculty Of Pharmaceutical Science Tokushima Bunri University

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