Chemical Constituents of Malagasy Liverworts, Part V : Prenyl Bibenzyls and Clerodane Diterpenoids with Nitric Oxide Inhibitory Activity from Radula appressa and Thysananthus spathulistipus

スポンサーリンク

概要

• 論文の詳細を見る

• 3β,4β:15,16-Diepoxy-13(16),14-clerodadiene (1) and a new clerodane diterpenoid designated thysaspathone (2) were isolated from the liverwort Thysananthus spathulistipus, while Radula appressa produced radulannin A (3), radulannin L (4), 2-geranyl-3,5-dihydroxybibenzyl (5), 2(S)-2-methyl-2-(4-methyl-3-pentenyl)-7-hydroxy-5-(2-phenylethyl) chromene (o-cannabichromene) (6), 6-hydroxy-4-(2-phenylethyl) benzofuran (7), and o-cannabicyclol (8). All of the isolated compounds inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and the greatest inhibition was attributed to compound 5, with an IC_<50> value of 4.5 μM.

• 公益社団法人日本薬学会の論文
• 2006-07-01

著者

• Takahara Yusuke

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• SOMA Gen-Ichiro

  Institute for Health Sciences, Tokushima Bunri University

• ASAKAWA Yoshinori

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• Asakawa Y

  Fac. Of Pharmaceutical Sciences Tokushima Bunri Univ.

• HARINANTENAINA Liva

  Faculty of Pharmaceutical Sciences, Tokushima Bunri University

• NISHIZAWA Takashi

  Institute for Health and Sciences, Tokushima Bunri University

• KOHCHI Chie

  Institute for Health and Sciences, Tokushima Bunri University

• Nishizawa Takashi

  Institute For Health And Sciences Tokushima Bunri University

• Soma Gen-ichiro

  Institute For Health And Sciences Tokushima Bunri University

• Harinantenaina Liva

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Kohchi Chie

  Institute For Health And Sciences Tokushima Bunri University

• Harinantenaina Liva

  Tokushima Bunri Univ. Tokushima Jpn

• Asakawa Y

  Tokushima Bunri Univ. Tokushima Jpn

• Asakawa Yoshinori

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

関連論文

• Expression of Nuclear Factor-kB, Tumor Necrosis Factor Receptor Type 1, and c-Myc in Human Astrocytomas
• The Novel Compounds That Activate Farnesoid X Receptor : the Diversity of Their Effects on Gene Expression
• Floral Scent Chemistry and Stamen Movement of Chimonanthus praecox (L.) Link (Calycanthaceae)
• Close Relationship between Mexican and Chinese Magnolia (Subtropical Disjunct of Magnoliaceae) Inferred from Molecular and Floral Scent Analyses
• Floral scent chemistry of mangrove plants
• Intraspecific Variation of Floral Scent Chemistry in Magnolia Kobus DC. (Magnoliaceae)
• Chemical Divergence in Floral Scents of Magnolia and Allied Genera (Magnoliaceae)(Reproductive Biology)
• Inhibitory activity of nitric oxide production in RAW 264.7 cells of daldinals A-C from the fungus Daldinia childiae and other metabolites isolated from inedible mushrooms
• Hydnellins A and B, Nitrogen-Containing Terphenyls from the Mushrooms Hydnellum suaveolens and Hydnellum geogerirum
• Inhibition of Nitric Oxide Production in RAW 264.7 Cells by Azaphilones from Xylariaceous Fungi(Molecular and Cell Biology)
• Pregnane-Type Steroids from the Inedible Mushroom Thelephora terrestris
• Tyromycic Acids F and G: Two New Triterpenoids from the Mushroom Tyromyces fissilis
• Curtisians M-Q: Five Novel p-Terphenyl Derivatives from the Mushroom Paxillus curtisii
• A Novel ent-Kaurane Diterpenoid from the Croton tonkinensis GAGNEP
• Two Novel Ravenelones from the Edible Mushroom Pulveroboletus ravenelii
• Chemical Constituents of Malagasy Liverworts, Part V : Prenyl Bibenzyls and Clerodane Diterpenoids with Nitric Oxide Inhibitory Activity from Radula appressa and Thysananthus spathulistipus
• Applications of Lipopolysaccharide Derived from Pantoea agglomerans (IP-PA1) for Health Care Based on Macrophage Network Theory
• Lipid Constituents of the New Zealand Liverwort Plagiochila circinalis
• New Humulane-Type Sesquiterpenes from the Liverworts Tylimanthus tenellus and Marchantia emarginata subsp. tosana
• New Bibenzyl Cannabinoid from the New Zealand Liverwort Radula marginata
• Occurrence of Polygodial and 1-(2, 4, 6-Trimethoxyphenyl)-but-2-en-1-one from Some Ferns and Liverworts : Role of Pungent Components in Bryophytes and Pteridophytes Evolution
• New ent-Kaurene-Type Diterpenoids Possessing Cytotoxicity from the New Zealand Liverwort Jungermannia Species
• Cytotoxic and Apoptosis-Inducing ent-Kaurane-Type Diterpenoids from the Japanese Liverwort Jungermannia truncata NEES
• The Essential Oil Constituents and Antimicrobial Activity of Anthemis aciphylla BOISS. var. discoidea BOISS.
• Studies on Cardiac Ingredients of Plants. XIII : Chemical Modification of Gitoxin to Cardiotonic Compounds without Vascular Contractile Effect
• AN UNUSUAL FLUORIDE-MEDIATED OXIDATION OF GITOXIN
• Clerodane-type Diterpenoids from the Japanese Liverwort Jungermannia infusca (MITT.) STEPH.
• New Sesqui- and Diterpenoids from the Japanese Liverwort Jungermannia infusca (MITT.) STEPH.
• Immunopotentiator from Pantoea agglomerans 1 (IP-PA1)は経口投与によりメラノーマ担癌マウスの生存を改善する
• New Sesquiterpenoids from the New Zealand Liverwort Chiloscyphus subporosus
• Terpenoids and Aromatic Compounds from the New Zealand Liverworts Plagiochila, Schistochila, and Heteroscyphus Species
• Biotransformation of hinesol Isolated from the Crude Drug Atractylodes Iancea by Aspergillus niger and Aspergillus cellulosae
• Structures of Four Novel Highly Oxygenated Labdane-Type Diterpenoids, Ptychantins F-I, from the Liverwort Ptychanthus striatus
• The Structures of Claudimerines-A and -B, Novel Bicoumarins from Citrus hassaku
• Momordica charantia Constituents and Antidiabetic Screening of the Isolated Major Compounds
• Novel Prenyl Bibenzyls from the New Zealand Liverwort Marsupidium epiphytum
• P-139 Synthetic Transformation of Ptychantin into Forskolin and 1,9-Dideoxyforskolin
• Isolation and Structures of New Cyclomyltaylane and ent-Chamigrane-Type Sesquiterpenoids from the Liverwort Reboulia hemishaerica and Their Biotransformation by the Fungus Aspergillus niger
• Biotransformation of Aristolane- and 2,3-Secoaromadendrane-Type Sesquiterpenoids Having a 1,1-Dimethylcyclopropane Ring by Chlorella fusca var. vacuolata, Mucor Species, and Aspergillus niger
• Highly Efficient Production of Nootkatone, the Grapefruit Aroma from Valencene, by Biotransformation(Communications to the Editor)
• Biotransformation of Citrus Aromatics Nootkatone and Valencene by Microorganisms
• Bazzanane Sesquiterpenoids from the New Zealand Liverwort Frullania falciloba
• Determination of the Absolute Configuration of Ginnol, a Long-chain Aliphatic Alcohol, by Use of a New Chiral Anisotropic Reagent
• Ornatipolide, a Novel Phenolic Metabolite from the Basidiomycete, Boletus ornatipes
• A Novel Skeletal Diterpenoid from the German Liverwort Barbilophozia hatcheri (EVANS) LOESKE
• Cytotoxic, radical scavenging and antimicrobial activities of sesquiterpenoids from the Tahitian liverwort Mastigophora diclados (Brid.) Nees (Mastigophoraceae)
• New Glycosides from the Japanese Fern Hymenophyllum barbatum
• New Bitter-Tasting Hemiterpene Glycosides from the Japanese Fern Hymenophyllum barbatum
• Hymenosides A-F, Six New Hemiterpene Glucosides from the Japanese Fern Hymenophyllum barbatum
• Sesquiterpene Lactones and Acetogenin Lactones from the Hepaticae and Chemosystematics of the Liverworts Frullania,Plagiochila and Porella
• Occurrence of a Bis-bibenzyl Derivative in the Japanese Fern Hymenophyllum barbatum : First Isolation and Identification of Perrottetin H from the Pteridophytes
• Occurrence of digalactopyranosylmonoacylglycerol in the liverwort Marchantia polymorpha
• Distribution of terpenoids and aromatic compounds in the liverwort Isotachis species
• Distribution of terpenoids and aromatic compounds in New Zealand liverworts
• New Chroman Derivatives from the Japanese Liverworts Metacalypogeia cordifolia and Cephalozia otaruensis
• Isoplagiochins C and D, New Type of Macrocyclic Bis(bibenzyls), Having Two Biphenyl Linkages from the Liverwort Plagiochila fruticosa
• PA33 CRYPTOPORIC ACIDS C, D, E, F, AND G, NOVEL BITTER DRIMANE SESQUITERPENOID ETHERS, FROM THE FUNGUS CRYPTOPORUS VOLVATUS
• PA135 NEOMARCHANTIN A AND B, FURTHER ISOLATION OF NEW MACROCYCLIC BIS(BIBENZYLS) FROM THE LIVERWORT
• Immune Recovery Effects of Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) on Low Antibody Productions in Response to Salmonella Enteritidis Vaccine and Sheep Red Blood Cells in Dexamethasone-Treated Stressed Chicken Models
• NOVEL SKEELETAL DITERPENOIDS FROM THE JAPANESE LIVERWORT PALLAVICINIA SUBCILIATA
• Occurrence of ent-Sesquiterpene in the Japanese Moss-Plagiomnium acutum : First Isolation and Identification of the ent-Sesqui-and Dolabellane-type Diterpenoids from the Musci
• Penicillium sclerotiorum Catalyzes the Conversion of Herbertenediol into Its Dimers : Mastigophorenes A and B
• Biotransformation of Terpenoids from the Crude Drugs and Animal Origin by Microorganisms
• Chemical Constituents of Malagasy Liverworts, Part II : Mastigophoric Acid Methyl Ester of Biogenetic Interest from Mastigophora diclados (Lepicoleaceae Subf. Mastigophoroideae)
• DUMORTENOLS, NOVEL SKELETAL SESQUITERPENOIDS FROM THE ARGENTINIAN LIVERWORT DUMORTIERA HIRSUTA
• EUDESMANE- TYPE SESQUITERPENOIDS FROM JAPANESE LIVERWORT FRULLANIA TAMARISCI SUBSP. OBSCURA
• Highly Oxygenated Guaianolides and Eudesman-12-oic Acids from Balsamorhiza sagittata and Balsamorhiza macrophylla
• ILVII-1 Recent Advances in Phytochemistry of Hepaticae(Chemistry and Biochemistry Related to Biodiversity)
• Oral Administration of Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) Improves the Survival of B16 Melanoma-Inoculated Model Mice
• 3G0924 コケ植物由来の大環状ビスビベンジル分子による抗インフルエンザウイルス活性(3G 蛋白質_構造3,日本生物物理学会第49回年会)
• Chemical Constituents of Malagasy Liverworts, Part III: Sesquiterpenoids from Bazzania decrescens and Bazzania madagassa
• New ent-Verticillane Diterpenoids from the Japanese Liverwort Jackiella javanica
• A NEW MONOCYCLIC DITERPENE FROM THE LIVERWORT JUNGERMANNIA INFUSCA (MITT.) STEPH.
• Diterpenoids and Aromatic Compounds from the Three New Zealand Liverworts Jamesoniella kirkii, Balantiopsis rosea, and Radula Species
• In vitro antitrypanosomal activity of some phenolic compounds from propolis and lactones from Fijian Kawa (Piper methysticum)
• Aromatic constituents of Cymbidium Great Flower Marie Laurencin and their antioxidative activity
• X-Ray Crystallographic Analysis of Methyl(1S,2R,5R,6S,7R)-5,6-Dimethyl-2(.OMEGA.-camphanoyloxy)bicyclo(4.3.0)nonane-7-carboxylate. Revision of the Absolute Configurations of the Liverwort Sesquiterpenoids(-)-Chiloscyphone and(+)-Chiloscypholone.

もっと見る 閉じる

スポンサーリンク