Evaluation of Electrical Stimulus Current Applied to Retina Cells for Retinal Prosthesis

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概要

• 論文の詳細を見る

• We have proposed a novel multilayer stacked retinal prosthesis chip based on three-dimensional integration technology. Implantable stimulus electrode arrays in polyimide flexible cables were fabricated for the electrical stimulation of the retina. To evaluate optimal retinal stimulus current, electrically evoked potential (EEP) was recorded in animal experiments using Japanese white rabbits. The EEP waveform was compared with visually evoked potential (VEP) waveform. The amplitude of the recorded EEP increased with stimulus current. The EEP waveform shows a similar behavior to the VEP waveform, indicating that the electrical stimulation of the retina can be exploited for the blind to perceive incident light to the retina.

• 2006-04-30

著者

• Tamai Makoto

  Ophthtalmology School Of Medicine Tohoku University

• Deguchi Jun

  Department Of Neurosurgery Osaka Medical College

• Fukushima Takafumi

  Department Of Advanced Materials Chemistry Graduate School Of Engineering Yokohama National Universi

• TOMITA Hiroshi

  Biofunctional Science, Tohoku University Biomedical Engineering Research Organization

• WATANABE Taiichiro

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University

• MOTONAMI Keita

  Department of Bioengineering and Robotics, Tohoku University

• Sugano Eriko

  Biofunctional Science Tohoku University Biomedical Engineering Research Organization

• Sato Manami

  Biofunctional Science Tohoku University Biomedical Engineering Research Organization

• Koyanagi Mitsumasa

  Department Of Bioengineering And Robotics Graduate School Of Engineering Tohoku University

• Kurino Hiroyuki

  Department Of Bioengineering And Robotics Graduate School Of Engineering Tohoku University

• Fukushima Takafumi

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan

• Sugano Eriko

  Biofunctional Science, Tohoku University Biomedical Engineering Research Organization, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

• Koyanagi Mitsumasa

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan

• Tamai Makoto

  Ophthalmology, School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

• Tamai Makoto

  Ophthtalmology, Tohoku University School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

• Deguchi Jun

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan

• Sato Manami

  Biofunctional Science, Tohoku University Biomedical Engineering Research Organization, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

• Motonami Keita

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan

• Watanabe Taiichiro

  Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 6-6-01 Aza Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan

• Tomita Hiroshi

  Biofunctional Science, Tohoku University Biomedical Engineering Research Organization, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

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