Effects of histamine on neurally mediated contraction of canine tracheal smooth muscle.
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概要
- 論文の詳細を見る
The neuromodulatory action of histamine was investigated in isolated canine trachea. Histamine potentiated the tracheal contraction induced by electrical field stimulation (EFS). The ACh release induced by EFS was potentiated by histamine. The potentiating effect was blocked by chlorpheniramine. These findings suggest that histamine potentiates the neurally mediated tracheal contraction and the potentiating effect may be related in part to the acceleration of the prejunctional release of ACh, which may be mediated by H<SUB>1</SUB>-receptors.
- 公益社団法人 日本薬理学会の論文
著者
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TSUCHIYA Yoshio
Department of Pharmacology, School of Pharmacy, Hoshi University
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Kasuya Yutaka
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Hosokawa Tomokazu
Department of Medicinal Plant Science, Hoshi University
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