DIRECT EFFECTS OF EXPECTORANTS ON THE TRACHEOBRONCHIAL SYSTEM IN VIVO
スポンサーリンク
概要
- 論文の詳細を見る
Direct actions of expectorants and other secretagogues on the airway system in vivo were investigated. Bronchosecretory, bronchomotor and bronchovascular responses were determined in pentobarbital-anesthetized dogs, the bronchial artery of which was perfused with blood in situ. Pilocarpine and histamine had a direct strong stimulating effect on the airway secretory cells, and potassium iodide and ammonium chloride had a mild effect, while bromhexine had almost no stimulant effect on those cells. Potassium iodide and bromhexine produced a slight bronchoconstriction. Contribution of a transvascular transudate to the respiratory tract fluid produced by expectorants or other secretagogues was suggested to be quite small.
- 公益社団法人日本薬学会の論文
著者
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MISAWA Miwa
Department of Pharmacology, School of Pharmacy, Hoshi University
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YANAURA Saizo
Department of Pharmacology, School of Pharmacy, Hoshi University
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HOSOKAWA Tomokazu
Department of Pharmacology, School of Pharmacy, Hoshi University
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Hosokawa Tomokazu
Department Of Pharmacology Hoshi College Of Pharmacy
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Misawa Miwa
Department Of Applied Pharmacology Hoshi University
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SASAGAWA SUMIKO
Department of Pharmacology, Hoshi College of Pharmacy
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Sasagawa Sumiko
Department Of Pharmacology Hoshi College Of Pharmacy
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Misawa Miwa
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Applied Pharmacology School Of Pharmacy Hoshi University
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Hukuhara T
Jikei Univ. School Of Medicine Tokyo
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Hosokawa Tomokazu
Department of Medicinal Plant Science, Hoshi University
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YANAURA Saizo
Department of Applied Pharmacology, School of Pharmacy, Hoshi University:Research Institute of Nippon Chemiphar, Co., Ltd.
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