BIOCHEMICAL ASPECTS OF EXPERIMENTAL BARBITAL DEPENDENCE III : EFFECT ON NEURAL ENERGY RESERVE SYSTEM
スポンサーリンク
概要
- 論文の詳細を見る
The effect of barbital intoxication on the neural energy reserve of rat was examined. The energy metabolism was depressed at dependent developing stage and recover to the non treated level at dependent stage. After with-drawal, rapid degradation of creatine phosphate and adenosine triphosphate was recognized. Later stage of withdrawal, the sum of creatine phosphate and adenosine triphosphate was decreased, and adenosine diphosphate and adenosine monophosphate was remarkably increased. These changes in neural energy reserve were parallel to the changes in adenylate cyclase activity and carbohydrate metabolism which were previously presentated. These changes may have possible role in development of drug dependence and or withdrawal.
- 1982-06-25
著者
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YANAURA Saizo
Department of Pharmacology, School of Pharmacy, Hoshi University
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KAKUNO Katsuhiko
Department of Pharmacology, School of Pharmacy, Hoshi University
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NAKAO Kenzo
Department of Pharmacology, School of Pharmacy, Hoshi University
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TAGASHIRA Eijiro
Department of Pharmacolory, School of Pharmacy, Hoshi University
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Kakuno Katsuhiko
Department Of Pharmacology School Of Pharmacy Hoshi University
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MATSUKAWA Keiko
Department of Pharmacology, Hoshi College of Pharmacy
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URANO Tomoko
Department of Pharmacology, Hoshi College of Pharmacy
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Nakao Kenzo
Department Of Pharmacology School Of Pharmacy Hoshi University
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Nakao Kenzo
Department Of Biochemistry Kyoto Pharmaceutical University
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Nakao Kenzo
Department Of Pharmacology Hoshi College Of Pharmacy
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Urano Tomoko
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Pharmacology School Of Pharmacy Hoshi University
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Matsukawa Keiko
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Applied Pharmacology School Of Pharmacy Hoshi University
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Tagashira Eijiro
Department Of Pharmacology Hoshi College Of Pharmacy
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Tagashira Eijiro
Department Of Pharmacology School Of Pharmacy Hoshi University
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TAGASHIRA Eijiro
Department of Pharmacology, Hoshi College of Pharmacy
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