BIOCHEMICAL ASPECTS IN THE EXPERIMENTAL BARBITAL DEPENDENCE IV : ITS EFFECT ON THE HEXOKINASE AND PHOSPHOFRUCTOKINASE ACTIVITIES IN THE RAT BRAIN
スポンサーリンク
概要
- 論文の詳細を見る
Effects of barbital dosing on the neural hexokinase (EC 2.7.1.1) and phosphofructokinase (EC 2.7.2.11) activities in the rat, were examined. The barbital dependence in the rat was acquired by giving the barbital-admixed food. These two enzyme activities were investigated in the following three dissected portions of the brain: cerebral cortex, brain stem and cerebellum. The both enzyme activities in these three portions were depressed by the barbital dosing; while them being increased at the early stage of its withdrawal. From these results, it is considered that the measurements of hexokinase and phosphofrubtokinase activities probably give a possibility to estimate the degree of barbital dependence and its withdrawal, and that these two enzyme activities can be good indeces in these conditions.
- 1983-05-25
著者
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YANAURA Saizo
Department of Pharmacology, School of Pharmacy, Hoshi University
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KAKUNO Katsuhiko
Department of Pharmacology, School of Pharmacy, Hoshi University
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NAKAO Kenzo
Department of Pharmacology, School of Pharmacy, Hoshi University
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Kakuno Katsuhiko
Department Of Pharmacology School Of Pharmacy Hoshi University
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Nakao Kenzo
Department Of Pharmacology School Of Pharmacy Hoshi University
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Nakao Kenzo
Department Of Biochemistry Kyoto Pharmaceutical University
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Nakao Kenzo
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Pharmacology School Of Pharmacy Hoshi University
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Yanaura Saizo
Department Of Pharmacology Hoshi College Of Pharmacy
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Yanaura Saizo
Department Of Applied Pharmacology School Of Pharmacy Hoshi University
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