INHIBITION BY PROPRANOLOL OF HIGH POTASSIUM-INDUCED CONTRACTIONS IN THE RAT VAS DEFERENS
スポンサーリンク
概要
- 論文の詳細を見る
High concentrations of propranolol (10^<-5>-3×10^<-4>M) inhibited in a dosedependent fashion and reversibly the maximal contractile responses produced by 150 mM K^+ in the rat vas deferens. 10^<-4>M propranolol and quinine produced similar inhibitory effects on the dose-response curves to K^+. Since norepinephrine-induced contractions were not substantially inhibited by quinine or propranolol, it was suggested that the two drugs may specifically inhibit the potassium-induced inflow of external calcium.
- 公益社団法人日本薬学会の論文
著者
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Takayama Chihiro
Department of Surgery, Kobe Children's Hospital
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Kasuya Yutaka
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Kasuya Yutaka
Department Of Pharmacology School Of Pharmacy Hoshi University
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Inagaki Osamu
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo:(pres
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Suzuki Nagao
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo
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Takayama Chihiro
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Science University Of Tokyo
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SUZUKI NAGAO
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kanazawa University
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