Effects of Long-Chain Fatty Acids and Fatty Alcohols on the Growth of Streptococcus mutans(Biological)
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概要
- 論文の詳細を見る
Minimal inhibitory concentrations (MICs) of a series of fatty acids and fatty alcohols against a cariogenic bacterium. Streptococcus mutans, were determined by a tube dilution technique. Among saturated fatty alcohols, tetradecanol and pentadecanol had the highest activity (MIC, 1.56μg/ml), while among monounsaturated fatty alcohols, 1OZ-pentadecenol had the strongest activity (MIC, 0.78 μg/ml). Saturated fatty acids showed relatively weak activity; tridecanoic acid had the highest activity among them (MIC, 12.5μg/ml). Among unsaturated fatty acids, 1OZ-heptadecenoic, 6Z-octadecenoic, 11Z-octadecenoic and 9Z,12Z-octadecadienoic acids had potent activity (MIC, 3.13μg/ml). The antibacterial activities of methyl-branched and hydroxyl fatty acids as well as long chain dicarboxylic acids were also investigated.
- 公益社団法人日本薬学会の論文
- 1987-08-25
著者
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KAKIUCHI Nobuko
Graduate School of Natural Science and Technology, Kanazawa University
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Kiuchi Fumiyuki
Faculty of Pharmacy, Keio University
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Namba Ttuneo
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Namba Tsuneo
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
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Hattori Masao
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
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Hattori Masao
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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HADA SUMITRA
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
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Namba T
Development For Drug-resources Research Institute For Wakan-yaku
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MIYACHI KUMI
Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University
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KAKIUCHI NOBUKO
Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University
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TSUDA YOSHISUKE
Faculty of Pharmaceutical Sciences, Kanazawa University
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Kikuchi F
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kiuchi Fumiyuki
Faculty Of Pharmaceutical Sciences Kanazawa University
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HADA Sakae
Kyoto Pharmaceutical University
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Kiuchi Fumiyuki
Graduate School Of Pharmaceutical Sciences Kyoto University
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Huang S‐l
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
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Miyachi K
Research Institute For Wakan-yaku Toyama Medical And Pharmaceutical University
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Kakiuchi N
Toyama Medical And Pharmaceutical Univ. Toyama Jpn
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Tsuda Y
Kanazawa Univ. Kanazawa Jpn
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Tsuda Yoshisuke
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kakiuchi N
Graduate School Of Natural Science And Technology Kanazawa University
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Kakiuchi Nobuko
Research Institute For Wakan-yaku Toyama Medical And Pharmaceutical University
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Namba Tsuneo
Research Institute For Wakan-yaku (traditional Sino-japanese Medicine) Toyama Medical And Pharmaceut
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Kakiuchi Nobuko
Graduate School Of Natural Sci. And Technol. Kanazawa Univ.
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Namba Tsuneo
Research Institute For Wakan-yaku (oriental Medicine) Toyama Medical And Pharmaceutical University
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Miyachi Kumi
Research Institute For Wakan-yaku Toyama Medical And Pharmaceutical University
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KAKIUCHI NOBUKO
Research Institute for Wakan-Yaku (Oriental Medicines)
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HATTORI MASAO
Research Institute for Wakan-Yaku (Oriental Medicines)
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