Cytotoxic Principles of a Bangladeshi Crude Drug, Akond Mul (Roots of Calotropis gigantea L.)

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概要

• 論文の詳細を見る

• Three cardenolide glycosides, calotropin (1), frugoside (2), and 4'-O-β-D-glucopyranosylfrugoside (3), were obtained as the cytotoxic principles of "akond mul" (roots of Calotropis gigantea L.). The cytotoxicity of these compounds against various cell lines of human and mouse origin was tested. They showed similar cell line selectivity to those of cardiac glycosides such as digoxin and ouabain : they are toxic to cell lines of human origin, but not to those from mouse at 2μg/ml.

• 公益社団法人日本薬学会の論文
• 1998-03-15

著者

• 田中 正一

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Kiuchi Fumiyuki

  Faculty of Pharmacy, Keio University

• Tanaka M

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• TANAKA Motohiro

  Cancer Research Institute, Kanazawa University

• SASAKI Takuma

  Cancer Research Institute, Kanazawa University

• HAQUE Mohammad

  Department of Ophthalmology, Gifu University School of Medicine

• Obata Tohru

  Department Of Experimental Therapeutics Cancer Research Institute Kanazawa University

• TSUDA YOSHISUKE

  Faculty of Pharmaceutical Sciences, Kanazawa University

• Haque Mohammad

  Department Of Pharmacy Rajshahi University

• Kiuchi F

  Graduate School Of Pharmaceutical Sciences Kyoto University

• Kikuchi F

  Faculty Of Pharmaceutical Sciences Kanazawa University:(present Address)graduate School Of Pharmaceu

• Kikuchi F

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Kiuchi Fumiyuki

  Faculty Of Pharmaceutical Sciences Kanazawa University

• FUKAO Yumi

  Faculty of Pharmaceutical Sciences, Kanazawa University

• MARUYAMA Takuro

  Faculty of Pharmaceutical Sciences, Kanazawa University

• OBATA Tohru

  Cancer Research Institute, Kanazawa University

• MIKAGE Masayuki

  Faculty of Pharmaceutical Sciences, Kanazawa University

• Kiuchi Fumiyuki

  Graduate School Of Pharmaceutical Sciences Kyoto University

• Kiuchi F

  Kanazawa Univ. Kanazawa Jpn

• Obara Takumi

  Department Of Experimental Therapeutics Cancer Research Institute Kanazawa University

• Fukao Yumi

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Obata Takaaki

  Department Of Experimental Therapeutics Cancer Research Institute Kanazawa University

• Sasaki Takuma

  Cancer Research Institute Kanazawa University

• Sasaki Takuma

  Department Of Experimental Therapeutics Cancer Research Insitute Kanazawa University

• Maruyama Takuro

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Tsuda Yoshisuke

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Tanaka Motohiro

  Cancer Research Institute Kanazawa University

• Mikage Masayuki

  Faculty Of Pharmaceuical Sciences Kanazawa University

• Mikage M

  Kanazawa Univ.

• Tsuda Y

  Faculty Of Pharmaceutical Sciences And High Technology Research Center Kobe Gakuin University

• Mikage Masayuki

  富山医科薬科大学和漢薬研究所

• Haque Mohammad

  Department Of Mechanical And Industrial Engineering Concordia University

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