Insight into Acid-Mediated Asymmetric Spirocyclization in the Presence of a Chiral Diol

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概要

• 論文の詳細を見る

• Asymmetric spirocyclization based on intramolecular conjugate addition using a combination of a Lewis acid and an optically active cyclohexane-1,2-diol has been studied in connection with 1) the effect of substituents on the cyclohexane-1,2-diol and 2) the effect of substituents on the substrate. This reaction was found to be both thermodynamically and kinetically controlled under restricted conditions.

• 公益社団法人日本薬学会の論文
• 2000-10-01

著者

• 田中 正一

  Graduate School Of Pharmaceutical Sciences Kyushu University

• TANAKA Masakazu

  Graduate School of Pharmaceutical Sciences, Kyushu University

• SUEMUNE Hiroshi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Sakai K

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Tanaka M

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• SAKAI Kiyoshi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Sakai K

  Tohoku Pharmaceutical Univ. Miyagi Jpn

• Sakai K

  Yaizu Suisan Kagaku Industry Co.

• KIGUCHI Toshihiro

  Graduate School of Pharmaceutical Sciences, Kyushu University

• TSURUSAKI Yuko

  Graduate School of Pharmaceutical Sciences, Kyushu University

• YAMADA Satoshi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• ASO Mariko

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Aso M

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Aso Mariko

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Tsurusaki Yuko

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Kiguchi Toshihiro

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Suemune H

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Suemune Hiroshi

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Tanaka Masakazu

  Graduate School Of Comprehensive Human Sciences University Of Tsukuba

• Yamada Satoshi

  Graduate School Of Industrial Technology Nihon University

• Yamada Satoshi

  Graduate School Of Pharmaceutical Sciences Kyushu University

• TANAKA Masakazu

  Graduate School of Agriculture, Hokkaido University

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