Aldol Condensation versus Conjugate Addition : Intramolecular Cyclization Using a Combination of Lewis Acid and 1,2-Diol
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概要
- 論文の詳細を見る
The reactivity of 3-substituted 4-methyl-4-(3-oxobutyl)-2-cyclohexen-1-ones (1) in the presence of a combination of a Lewis acid and a 1,2-diol was studied. The results suggest several factors that influence 6-membered ring formation, including two types of intramolecular aldol reaction and intramolecular 1,4-addition, due to the C3-substituent, Lewis acid, and the presence of diol. In this study, novel methodology to prepare two types of decalin skeleton could be developed.
- 公益社団法人日本薬学会の論文
- 2000-08-01
著者
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SUEMUNE Hiroshi
Graduate School of Pharmaceutical Sciences, Kyushu University
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Suemune Hiroshi
Graduate School Of Pharmaceutical Sciences Kyushu University
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Yamada Satoshi
Graduate School Of Industrial Technology Nihon University
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