Asymmetric Synthesis and Conformational Analysis of α,α-Disubstituted α-Amino Acids and Their Peptides

スポンサーリンク

概要

• 論文の詳細を見る
• 2002-03-01

著者

• 田中 正一

  Graduate School Of Pharmaceutical Sciences Kyushu University

• KURIHARA Masaaki

  Division of Organic Chemistry, National Institute of Health Sciences

• DEMIZU Yosuke

  Graduate School of Pharmaceutical Sciences, Kyushu University

• TANAKA Masakazu

  Graduate School of Pharmaceutical Sciences, Kyushu University

• SUEMUNE Hiroshi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• OBA Makoto

  Graduate School of Pharmaceutical Sciences, Kyushu University

• NISHIMURA Shin

  Graduate School of Pharmaceutical Sciences, Kyushu University

• HAYASHIDA Kazuhiro

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Hayashida Kazuhiro

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Oba Makoto

  Graduate School Of Information Shizuoka University

• Demizu Yosuke

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Suemune H

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Suemune Hiroshi

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Tanaka Masakazu

  Graduate School Of Comprehensive Human Sciences University Of Tsukuba

• Nishimura Shin

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Kurihara M

  Division Of Organic Chemistry National Institute Of Health Sciences

• Kurihara Masaaki

  Division Of Organic Chemistry National Institute Of Health Sciences

• Demizu Yosuke

  Division Of Organic Chemistry National Institute Of Health Sciences

• Demizu Yosuke

  Division Of Organic Chemistry National Institute Of Health Sciences Ministry Of Health And Welfare

• Oba Makoto

  Graduate School Of Biomedical Sciences Nagasaki University

• TANAKA Masakazu

  Graduate School of Agriculture, Hokkaido University

関連論文

• Computational Study on Secondary Structure of Oligopeptides Containing α,α-Disubstituted α-Amino Acids
• Controlling 3_-Helix and α-Helix of Short Peptides in the Solid State
• Controlling Helical Secondary Structures by Cyclic α,α-Disubstituted Amino Acids Having Side-Chain Chiral Centers
• Computational Study on Helical Structures of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted α-Amino Acids
• Synthesis of Optically Active Cyclic α,α-Disubstituted Amino Acids by Enzymatic Kinetic Resolution and Conformational Analysis of Their Peptides
• 非タンパク質構成アミノ酸の設計・合成とそのペプチドの2次構造
• Computational Study on Conformation of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted α-Amino Acids
• Synthesis of Various Chiral Cyclic α,α-Disubstituted Amino Acids and Conformational Analysis of Their Peptides
• Chiral Cyclic α,α-Disubstituted α-Amino Acids Bearing Two Chiral Centers and Conformation of Their Peptides
• Computational Study on Conformation of Oligopeptides Controlled by Side Chain Chiralities of α-Amino Acids
• Relationship between α-Amino Acid Chiral Center and Helical Secondary Structure of Its Oligopeptides
• Prediction of Helical Screw Sense of Oligopeptides Containing Chiral Amino Acids : Computational Study
• Controlling the Secondary Structure of Aib Peptides by N-Terminal Proline
• Synthesis of Cyclic α, α-Disubstituted Amino Acids Bearing a γ-Nitrogen Atom
• Controlling the Helical Screw Sense of Oligopeptides by Chiral Cyclic α, α-Disubstituted α-Amino Acid
• Conformation of Oligopeptides Containing Chiral α, α-Disubstituted Amino Acids : Computational Study
• Asymmetric Synthesis and Conformational Analysis of α,α-Disubstituted α-Amino Acids and Their Peptides
• α, α-ジ置換アミノ酸よりなるペプチドのコンフォメーションと分子設計
• Solid-State Conformation of a Hybrid Tripeptide between β-Amino Acid ; 8-Aminocyclooct-4-enecarboxylic Acid and 2-Aminoisobutyric Acid
• Molecular Mechanics Study on Conformational Analysis of Homooligopeptides Prepared from α, α-Disubstituted Amino Acids
• 1,2-ジオール分子認識に基づく選択的分子変換反応
• 1-アルコキシ-2,2,2-トリフロロエチル基で保護したL-プロリノール誘導体の電極酸化
• Centrosome amplification in adult T-cell leukemia and human T-cell leukemia virus type 1 Tax-induced human T cells
• Integration of human T-cell leukemia virus type 1 in genes of leukemia cells of patients with adult T-cell leukemia
• Asymmetric Rh-Catalyzed Intermolecular Hydroacylation of 1,5-Hexadiene with Salicylaldehyde
• Application of Rh-Catalyzed Cyclization to the Formation of a Chiral Quaternary Carbon
• Deletion Mutants of Human Deoxycytidine Kinase mRNA in Cells Resistant to Antitumor Cytosine Nucleosides
• Nucleosides and Nucleotides. 186. Synthesis and Biological Activities of Pyrimidine Carbocyclic Nucleosides with a Hydroxyamino Group Instead of a Hydroxymethyl Group at the 4'-Position of the Sugar Moiety
• New Neplanocin Anallogues. VIII. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A
• In Vitro and in Vivo Antitumor Activity of a Novel Nucleoside, 4'-Thio-2'-deoxy-2'-methylidenecytidine
• Synthesis of N-Glycolyl-8-O-sulfoneuraminic Acid
• Synthesis of Fluorescent 4-Methyl-7-thiocoumaryl S-Glycosides of Sialic Acid
• Facile Synthesis of 4-Acylamino-2,6-anhydro-2,3,4-trideoxy-D-glycero-D-galacto-non-2-enoic Acids
• Comparison of Mammary Gland Growth and Some Physiological Parameters in a High Mammary Tumor Strain of SHN Mice and ICR, Most Popular and 'Normal' Mice
• Capacity Improvement of Multihop Inter-Vehicle Communication Networks by STBC Cooperative Relaying(Advances in Ad Hoc Mobile Communications and Networking)
• Cytotoxic Principles of a Bangladeshi Crude Drug, Akond Mul (Roots of Calotropis gigantea L.)
• Pregnane-Type Steroids from the Inedible Mushroom Thelephora terrestris
• Tyromycic Acids F and G: Two New Triterpenoids from the Mushroom Tyromyces fissilis
• Curtisians M-Q: Five Novel p-Terphenyl Derivatives from the Mushroom Paxillus curtisii
• Two Novel Ravenelones from the Edible Mushroom Pulveroboletus ravenelii
• Prediction of Helical Screw Sense of Oligopeptides Containing Chiral α, α-Disubstituted Amino Acids
• Synthesis and Anti-HIV-1 and Anti-HCMV Activity of 1-Substituted 3-(3,5-Dimethylbenzyl) uracil Derivatives
• ANTITUMOR ACTIVITY OF AQUEOUS EXTRACTS OF MARIRE ANIMALS
• EFFECT OF SERUM FROM MICE TREATED WITH ANTITUMOR POLYSACCHARIDE ON EXPRESSION OF CYTOTOXICITY BY MOUSE PERITONEAL MACROPHAGES
• Ring Contraction of α,β-Unsaturated Cyclic Amines with cis-Dihydroxylation at the α,β-Position
• Superoxide Anion Generation via Electron-Transfer Oxidation of Catechin Dianion by Molecular Oxygen in an Aprotic Medium
• Immunohistological Study of the Localization of Collagen Types I-XI in Bovine Term Placenta
• Immunohistological Study of the Localization of Collagen Types I-XI in Bovine Term Placenta
• Russujaponols G-L, Illudoid Sesquiterpenes, and Their Neurite Outgrowth Promoting Activity from the Fruit Body of Russula japonica
• Novel Abietane Diterpenoids and Aromatic Compounds from Cladonia rangiferina and Their Antimicrobial Activity against Antibiotics Resistant Bacteria
• Biotransformation of hinesol Isolated from the Crude Drug Atractylodes Iancea by Aspergillus niger and Aspergillus cellulosae
• Stereoselective Epoxidation of Acyclic Allylic Ethers Using Ketone-Oxone^ System
• Reduction of human T-cell leukemia virus type-1 infection in mice lacking nuclear factor-κB-inducing kinase
• Cell^free Human T-cell Leukemia Virus Type 1 Binds to and Efficiently Enters Mouse Cells
• Human T-cell Leukemia Virus Type 1 Can Infect a Wide Variety of Cells in Mice
• Synthesis, Conformation, and Chemical Properties of New Mini Parallel Double-Stranded Peptides Conjugated with -Phe-Phe- and -Phe-Phe-X- Sequences
• Insight into Acid-Mediated Asymmetric Spirocyclization in the Presence of a Chiral Diol
• Antisweet Natural Products. XV. Structures of Jegosaponins A-D from Styrax japonica SIEB. et ZUCC.
• Pregnane Glygosides, Gymnepregosides G-Q from the Roots of Gymnema alternifolium
• ortho-Halogeno Substituents Effect in Asymmetric Cyclization of 4-Aryl-4-pentenals Using a Rhodium Catalyst
• Enantio- and Diastereoselective Synthesis of N-[(1R, 2R, 3R, 4R)-2,3-Diacetoxy-4-(acetoxymethyl)cyclopentyl]acetamide, a Synthetic Key Intermediate of (+)-Cyclaradine
• Synthesis of Optically Active Bicyclo[3.3.0]octane Skeleton Using Transannular Reaction
• Computational Study on Helical Structure of α,α-Disubstituted Oligopeptides Containing Chiral α-Amino Acids
• ピペリジン骨格を有する非天然型アミノ酸の合成法 (特集 アミノ酸合成の先端研究)
• A Novel Method of Preparing Amine-Modifying C-4' Oxidized Nucleotide
• Cooperative Strand Invasion by Peptide Nucleic Acid
• Design and Synthesis of Chiral Cyclic α,α-Disubstituted Amino Acid Having Azido Functions, and Its Oligopeptides
• イソバリンより構成されるホモペプチドの分子力学法によるコンフォメーション解析
• Sex Pheromone of the Rice Stem Borer, Chilo suppressalis (WALKER) (Lepidoptera : Pyralidae) : the Third Component, Z-9-Hexadecenal
• Sex Pheromone Content in Female Chilo suppressails WALKER (Lepidoptera : Pyralidae) Reared on Artificial Diets
• Release Rate and Distance Effects of Evaporators with Z-11-Hexadecenal and Z-5-Hexadecene on Disruption of Male Orientation in the Rice Stem Borer Moth, Chilo suppressalis WALKER (Lepidoptera : Pyralidae)
• Disruption of Sex Pheromone Communication in the Rice Stem Borer Moth, Chilo suppressalis WALKER (Lepidoptera : Pyralidae), with Sex Pheromone Components and Their Analogues
• Factors Improving Field Trapping of Male Rice Stem Borer Moth, Chilo suppressalis WALKER (Lepidoptera : Pyralidae), by Using Synthetic Sex Attractant
• Disruption of Sex Attraction in the Rice Stem Borer Moth, Chilo suppressalis WALKER, with Components of the Sex Pheromone and Related Chemicals
• Hardness Controlled Enzymes and Electronegativity Controlled Enzymes : Role of an Absolute Hardness-Electronegativity (η-χ) Activity Diagram as a Coordinate for Biological Activities
• Design and Synthesis of Chiral α, α-Disubstituted Amino Acids and Conformational Study of Their Oligopeptides
• Artificial Diet for the Large Cabbage-Heart Caterpillar, Crocidolomia binotalis (ZELL.) (Lepidoptera : Pyralidae)
• DNAを不斉触媒として利用した不斉Diels-Alder反応(A・化学系薬学)
• Dialkyl Bisphosphonate Platinum(II) Complex as a Potential Drug for Metastatic Bone Tumor
• Identification of Mutaprodenafil in a Dietary Supplement and Its Subsequent Synthesis
• Conformation of Peptides Prepared from α-Ethylated α, α-Disubstituted Amino Acids
• Synthesis of Chiral Cyclic α, α-Disubstituted α-Amino Acid and Its Peptides
• P-261 SYNTHETIC STUDY OF CHONDROSIAMIDE A, A CYCLIC DEPSIPEPTIDE FROM THE MARINE SPONGE CHONDROSIA CHUCALLA
• Design of Short α-Helical Peptides for Transcriptional Inhibitor of Nuclear Receptor
• Computational Study on Conformation of Oligopeptides Containing α,α-Disubstituted Amino Acids
• Stabilized α-Helical Peptide-Catalyzed Asymmetric Epoxidation of Chalcone Derivatives
• Synthesis of 4-Substituted Chiral PNA Monomers
• Conformational Studies of Diastereomeric -Leu-Aib- Peptides
• ペプチドフォールドマーのナノ二次構造を利用した抗菌活性ペプチドの設計-開発 (平成17年度研究奨励金受領報告) -- (研究課題 分子標的低分子化合物の開発研究)
• LASR : A Load-Aware Source Routing Protocol in a High Load Ad-hoc Network and Its Evaluation, Vol.J86-B,No.3, pp.322-332
• Aldol Condensation versus Conjugate Addition : Intramolecular Cyclization Using a Combination of Lewis Acid and 1,2-Diol
• α,α-ジ置換アミノ酸イソバリンおよびジエチルグリシンより構成されるホモペプチドの分子力学法によるコンフォメーション解析
• 1F1312 アメーバ運動の3次元モデル(数理生物学1,第49回日本生物物理学会年会)
• Design and Synthesis of Conformational Freedom Restricted Endomorphin-2 Analogues
• Design of Stable Helical Peptides
• Design of Stapled Helical Peptides for Catalytic Enantioselective Epoxidation of α,β-Unsaturated Ketones
• Synthesis and Conformational Analysis of Peptides Composed of Chiral Five-Membered Ring Amino Acids
• Synthesis of β-Chiral Peptide Nucleic Acids and Their DNA Binding Properties
• Intracellular Internalization Mechanism of Protein Transfection Reagents
• Synthesis of Chiral Five-membered Ring Amino Acids wtih an Azido Group, and Their Peptides

もっと見る 閉じる

スポンサーリンク