Synthesis of Optically Active Bicyclo[3.3.0]octane Skeleton Using Transannular Reaction

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概要

• 論文の詳細を見る

• Optically active 5-cyclooctene-1,2-diol derivatives prepared by an enzymatic procedure have been converted into bicyclo[3.3.0]octane derivatives by transannular reaction with complete inversion of the stereogenic center linked to the leaving group. Formal synthesis of (+)-iridomyrmecin has been achieved starting from (S, S)-5-cyclooctene-1,2-diol by using this process.

• 公益社団法人日本薬学会の論文
• 1998-01-15

著者

• 田中 正一

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Sakai K

  Graduate School Of Pharmaceutical Sciences Kyushu University

• TANAKA Masakazu

  Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology

• Tanaka M

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Horikawa Tamaki

  Faculty Of Pharmaceutical Sciences Kyushu University

• Sakai K

  Tohoku Pharmaceutical Univ. Miyagi Jpn

• SUEMUNE HIROSHI

  Faculty of Pharmaceutical Sciences, Kyushu Uinversity

• Sakai K

  Yaizu Suisan Kagaku Industry Co.

• SAKAI Kiyoshi

  Kyushu Women's University

• NORIMINE Yoshihiko

  Faculty of Pharmaceutical Sciences, Kyushu University

• Suemune H

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Suemune Hiroshi

  Faculty Of Pharmaceutical Sciences Kyushu Uinversity

• Norimine Yoshihiko

  Faculty Of Pharmaceutical Sciences Kyushu University

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