Conformational Studies of Diastereomeric -Leu-Aib- Peptides

スポンサーリンク

概要

• 論文の詳細を見る
• 2011-03-01

著者

• 田中 正一

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Sato Y

  Faculty Of Pharmaceutical Sciences Hokuriku University

• Sato Y

  Division Of Organic Chemistry National Institute Of Health Sciences

• Sato Yukiko

  Division Of Organic Chemistry National Institute Of Health Sciences

• Okuda Haruhiro

  Division Of Organic Chemistry National Institute Of Health Sciences

• KURIHARA Masaaki

  Division of Organic Chemistry, National Institute of Health Sciences

• DOI Mitsunobu

  Osaka University of Pharmaceutical Sciences

• Okuda Haruhiro

  Division Of Organic Chemistry National Institute Of Health Sciences (nihs)

• 出水 庸介

  長崎大学大学院医歯薬学総合研究科

• 田中 誠

  School Of Pharmaceutical Sciences Kitasato University

• Demizu Yosuke

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Demizu Yosuke

  Faculty Of Pharmaceutical Sciences At Kagawa Campus Tokushima Bunri University

• Tanaka Masakazu

  Graduate School Of Comprehensive Human Sciences University Of Tsukuba

• Kurihara M

  Division Of Organic Chemistry National Institute Of Health Sciences

• Kurihara Masaaki

  Division Of Organic Chemistry National Institute Of Health Sciences

• Tanaka M

  Nihon Univ. Fujisawa‐shi Jpn

• Demizu Yosuke

  Division Of Organic Chemistry National Institute Of Health Sciences

• Demizu Yosuke

  Division Of Organic Chemistry National Institute Of Health Sciences Ministry Of Health And Welfare

• Tanaka Masami

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Okuda Haruhiro

  Division of Drugs, National Institute of Health Sciences

• Tanaka Masakazu

  Graduate School of Biomedical Sciences, Nagasaki University

• TANAKA Masakazu

  Graduate School of Agriculture, Hokkaido University

関連論文

• Development of Des-Fatty Acyl-Polymyxin B Decapeptide Analogs with Pseudomonas aeruginosa-Specific Antimicrobial Activity
• Contribution of Each Amino Acid Residue in Polymyxin B_3 to Antimicrobial and Lipopolysaccharide Binding Activity
• Des-Fatty Acyl-Polymyxin B Decapeptide Analogs with Antimicrobial Activity Specifically against Pseudomonas aeruginosa
• Semi-synthesis of Polymyxin B (2-10) and Colistin (2-10) Analogs Employing the Trichloroethoxycarbonyl (Troc) Group for Side Chain Protection of α, γ-Diaminobutyric Acid Residues
• Chemical Conversion of Natural Polymyxin B and Colistin to Their N-Terminal Derivatives
• Semi-Synthesis of Polymyxin B-(2-10) Analogs Employing the Trichloroethoxycarbonyl (Troc) Group for Side Chain Protection of 2,4-Diaminobutyric Acid Residues
• Structure-Activity Relationships of Neuromedin U. V. Study on the Stability of Porcine Neuromedin U-8 at the C-Terminal Asparagine Amide under Mild Alkaline and Acidic Conditions
• Antimicrobial Activity of Des-Fatty Acyl-Polymyxin B Decapeptide N-Terminal Analogs
• The Contribution of the N-Terminal Structure of Polymyxin B Peptides to Antimicrobial and Lipopolysaccharide Binding Activity
• Antimicrobial Activity of Polymyxin B_3 Analogs modified at the Hydrophobic Amino Acids
• Involvement of Electron Transfer in the Radical-scavenging Reaction of Resveratrol
• Computational Study on Secondary Structure of Oligopeptides Containing α,α-Disubstituted α-Amino Acids
• Controlling 3_-Helix and α-Helix of Short Peptides in the Solid State
• Controlling Helical Secondary Structures by Cyclic α,α-Disubstituted Amino Acids Having Side-Chain Chiral Centers
• Computational Study on Helical Structures of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted α-Amino Acids
• Synthesis of Optically Active Cyclic α,α-Disubstituted Amino Acids by Enzymatic Kinetic Resolution and Conformational Analysis of Their Peptides
• 非タンパク質構成アミノ酸の設計・合成とそのペプチドの2次構造
• Computational Study on Conformation of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted α-Amino Acids
• Synthesis of Various Chiral Cyclic α,α-Disubstituted Amino Acids and Conformational Analysis of Their Peptides
• Chiral Cyclic α,α-Disubstituted α-Amino Acids Bearing Two Chiral Centers and Conformation of Their Peptides
• Computational Study on Conformation of Oligopeptides Controlled by Side Chain Chiralities of α-Amino Acids
• Relationship between α-Amino Acid Chiral Center and Helical Secondary Structure of Its Oligopeptides
• Prediction of Helical Screw Sense of Oligopeptides Containing Chiral Amino Acids : Computational Study
• Controlling the Secondary Structure of Aib Peptides by N-Terminal Proline
• Synthesis of Cyclic α, α-Disubstituted Amino Acids Bearing a γ-Nitrogen Atom
• Controlling the Helical Screw Sense of Oligopeptides by Chiral Cyclic α, α-Disubstituted α-Amino Acid
• Conformation of Oligopeptides Containing Chiral α, α-Disubstituted Amino Acids : Computational Study
• Asymmetric Synthesis and Conformational Analysis of α,α-Disubstituted α-Amino Acids and Their Peptides
• α, α-ジ置換アミノ酸よりなるペプチドのコンフォメーションと分子設計
• Solid-State Conformation of a Hybrid Tripeptide between β-Amino Acid ; 8-Aminocyclooct-4-enecarboxylic Acid and 2-Aminoisobutyric Acid
• Molecular Mechanics Study on Conformational Analysis of Homooligopeptides Prepared from α, α-Disubstituted Amino Acids
• EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives
• Asymmetric Rh-Catalyzed Intermolecular Hydroacylation of 1,5-Hexadiene with Salicylaldehyde
• Application of Rh-Catalyzed Cyclization to the Formation of a Chiral Quaternary Carbon
• Four Guaianolides from Sinodielsia yannanensis
• Crystal Structures of Acetyl Gramicidin S Analogues
• Structual Analyses for Asymmetric Derivatives of Ascidiacyclamide by X-ray Diffraction and NMR Spectroscopy
• Crystal Structure of Hybrid Dipeptide, (2-Carboxyethyl)-cytosine-1-yl-L-threonine Monohydrate
• Crystal Structure of Hybrid Dipeptide, Cytosinyl-L-tyrosine
• Conformation and Sodium Coordinate Forms of an Endothelin Inhibitor BQ123・Na, Cyclo(-D-Trp-D-Asp^~-Pro-D-Val-Leu-)・Na^+, in the Crystal
• Crystal Structure of 2-[N-(t-Butoxycarbonyl)amino]-4-(thymin-1-yl)-butyric Acid Methyl Ester
• Polymorphism and C-H…O Interaction of Wortmannin, a Phosphatidylinositol 3-Kinase Inhibitor
• Crystal Structure of 3, 4-Dihydroxy-6-fluoro-DL-phenylalanine Monohydrate Used as a Positron Emission Tomography Imaging Ligand
• Fluorophotometric Determination of Hydrogen Peroxide and Other Reactive Oxygen Species with Fluorescein Hydrazide (FH) and Its Crystal Structure
• Absolute Stereostructures of Cell-adhesion Inhibitors, Peribysins A, E, F and G, Produced by a Sea Hare-derived Periconia sp
• Hydrogen Bond between Water and the Phenyl Ring in the Structure of a Dipeptide H-Phe-Leu-NH_2 at 90 K and the Structure-based Energy Estimations
• Interaction Modes between N7-Quarternized Guanine and Cytosine-Containing Dipeptides
• Deletion Mutants of Human Deoxycytidine Kinase mRNA in Cells Resistant to Antitumor Cytosine Nucleosides
• Nucleosides and Nucleotides. 186. Synthesis and Biological Activities of Pyrimidine Carbocyclic Nucleosides with a Hydroxyamino Group Instead of a Hydroxymethyl Group at the 4'-Position of the Sugar Moiety
• New Neplanocin Anallogues. VIII. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A
• In Vitro and in Vivo Antitumor Activity of a Novel Nucleoside, 4'-Thio-2'-deoxy-2'-methylidenecytidine
• Synthesis of N-Glycolyl-8-O-sulfoneuraminic Acid
• Synthesis of Fluorescent 4-Methyl-7-thiocoumaryl S-Glycosides of Sialic Acid
• Facile Synthesis of 4-Acylamino-2,6-anhydro-2,3,4-trideoxy-D-glycero-D-galacto-non-2-enoic Acids
• Cytotoxic Principles of a Bangladeshi Crude Drug, Akond Mul (Roots of Calotropis gigantea L.)
• Pregnane-Type Steroids from the Inedible Mushroom Thelephora terrestris
• Tyromycic Acids F and G: Two New Triterpenoids from the Mushroom Tyromyces fissilis
• Curtisians M-Q: Five Novel p-Terphenyl Derivatives from the Mushroom Paxillus curtisii
• Two Novel Ravenelones from the Edible Mushroom Pulveroboletus ravenelii
• Gene expression profiles of hepatotoxin-treated human hepatocytes can be used to cluster unknown compounds according to their mode of action(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
• Prediction of Helical Screw Sense of Oligopeptides Containing Chiral α, α-Disubstituted Amino Acids
• ANTITUMOR ACTIVITY OF AQUEOUS EXTRACTS OF MARIRE ANIMALS
• EFFECT OF SERUM FROM MICE TREATED WITH ANTITUMOR POLYSACCHARIDE ON EXPRESSION OF CYTOTOXICITY BY MOUSE PERITONEAL MACROPHAGES
• Superoxide Anion Generation via Electron-Transfer Oxidation of Catechin Dianion by Molecular Oxygen in an Aprotic Medium
• Present State of New Chiral Drug Development and Review in Japan
• Russujaponols G-L, Illudoid Sesquiterpenes, and Their Neurite Outgrowth Promoting Activity from the Fruit Body of Russula japonica
• Novel Abietane Diterpenoids and Aromatic Compounds from Cladonia rangiferina and Their Antimicrobial Activity against Antibiotics Resistant Bacteria
• Novel Des-Fatty Acyl-Polymyxin B Derivatives with Pseudomonas aeruginosa-Specific Antimicrobial Activity
• Biotransformation of hinesol Isolated from the Crude Drug Atractylodes Iancea by Aspergillus niger and Aspergillus cellulosae
• Stereoselective Epoxidation of Acyclic Allylic Ethers Using Ketone-Oxone^ System
• Synthesis, Conformation, and Chemical Properties of New Mini Parallel Double-Stranded Peptides Conjugated with -Phe-Phe- and -Phe-Phe-X- Sequences
• Insight into Acid-Mediated Asymmetric Spirocyclization in the Presence of a Chiral Diol
• Antisweet Natural Products. XV. Structures of Jegosaponins A-D from Styrax japonica SIEB. et ZUCC.
• Pregnane Glygosides, Gymnepregosides G-Q from the Roots of Gymnema alternifolium
• ortho-Halogeno Substituents Effect in Asymmetric Cyclization of 4-Aryl-4-pentenals Using a Rhodium Catalyst
• Enantio- and Diastereoselective Synthesis of N-[(1R, 2R, 3R, 4R)-2,3-Diacetoxy-4-(acetoxymethyl)cyclopentyl]acetamide, a Synthetic Key Intermediate of (+)-Cyclaradine
• Synthesis of Optically Active Bicyclo[3.3.0]octane Skeleton Using Transannular Reaction
• Computational Study on Helical Structure of α,α-Disubstituted Oligopeptides Containing Chiral α-Amino Acids
• ピペリジン骨格を有する非天然型アミノ酸の合成法 (特集 アミノ酸合成の先端研究)
• Cooperative Strand Invasion by Peptide Nucleic Acid
• Antimicrobial Activity of Various Aminocyclohexylcarbonyl-polymyxin B (2-10) Derivatives
• Specificity of splenopancreatic field abnormality in trisomy 13 syndrome : Macroscopic and histological analysis in 21 autopsy cases
• Gene mutation analysis and immunohistochemical study of β-catenin in odontogenic tumors
• Design and Synthesis of Chiral Cyclic α,α-Disubstituted Amino Acid Having Azido Functions, and Its Oligopeptides
• イソバリンより構成されるホモペプチドの分子力学法によるコンフォメーション解析
• Hardness Controlled Enzymes and Electronegativity Controlled Enzymes : Role of an Absolute Hardness-Electronegativity (η-χ) Activity Diagram as a Coordinate for Biological Activities
• Conformation of Peptides Prepared from α-Ethylated α, α-Disubstituted Amino Acids
• Time-Dependent Changes of Oxytocin Using 1H-NMR Coupled with Multivariate Analysis: a New Approach for Quality Evaluation of Protein/Peptide Biologic Drugs
• Synthesis of Chiral Cyclic α, α-Disubstituted α-Amino Acid and Its Peptides
• Design of Short α-Helical Peptides for Transcriptional Inhibitor of Nuclear Receptor
• Computational Study on Conformation of Oligopeptides Containing α,α-Disubstituted Amino Acids
• Stabilized α-Helical Peptide-Catalyzed Asymmetric Epoxidation of Chalcone Derivatives
• Conformational Studies of Diastereomeric -Leu-Aib- Peptides
• α,α-ジ置換アミノ酸イソバリンおよびジエチルグリシンより構成されるホモペプチドの分子力学法によるコンフォメーション解析
• Design and Synthesis of Conformational Freedom Restricted Endomorphin-2 Analogues
• Design of Stable Helical Peptides
• Design of Stapled Helical Peptides for Catalytic Enantioselective Epoxidation of α,β-Unsaturated Ketones
• Synthesis and Conformational Analysis of Peptides Composed of Chiral Five-Membered Ring Amino Acids
• Synthesis and Enhanced Radical Scavenging Activity of a Conformationally Constrained Epigallocatechin Analogue
• Rapid and Sensitive Method for Measuring the Plasma Concentration of Doxorubicin and Its Metabolites

もっと見る 閉じる

スポンサーリンク