Synthetic Studies on Glycosphingolipids from Protostomia Phyla: Synthesis of Glycosphingolipids from the Parasite Schistosoma mansoni
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概要
- 論文の詳細を見る
Synthetic access to three neutral glycosphingolipids from the parasite Schistosoma mansoni adult worm has been achieved. These structures differ significantly from those of other parasites and exhibit a unique structural motif termed “schisto-core” consisting of GalNAcβ1→4Glcβ1→sequence. We have synthesized glycosphingolipids, β-D-GalNAcp-(1→4)-β-D-Glcp-(1→1)Cer (1), β-D-GlcNAcp-(1→3)-β-D-GalNAcp-(1→4)-β-D-Glcp-(1→1)Cer (2) and β-D-Galp-(1→4)-β-D-GlcNAcp-(1→3)-β-D-GalNAcp-(1→4)-β-D-Glcp-(1→1)Cer (3).
著者
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Kiuchi Fumiyuki
Faculty of Pharmacy, Keio University
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TAKEDA Tadahiro
Faculty of Pharmacy, Keio University
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Kiuchi Fumiyuki
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kanaya Takayuki
Faculty of Pharmacy, Keio University
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Yagi Satomi
Faculty of Pharmacy, Keio University
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Schweizer Frank
Department of Chemistry, University of Manitoba
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Hada Noriyasu
Faculty of Pharmacy, Keio University
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Schweizer Frank
Department Of Chemistry The University Of Manitoba
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Takeda Tadahiro
Faculty Of Pharmacy Keio University
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Kanaya Takayuki
Faculty of Health and Welfare Hiroshima International University
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