Studies on Crude Drugs Effective on Visceral Larva Migrans. VI : Identification of Nematocidal Principles in Tephrosia purpurea PERS.

スポンサーリンク

概要

• 論文の詳細を見る

• The Sri Lankan traditional medicine "Pilamul" (root of Tephrosia purpurea PERS.) showed strong nematocidal activity on the larva of Toxocara canis. The following compounds were isolated and identified: lanceolatin B (I), α-toxicarol (II), deguelin (III), tephrosin (IV), O-methylobovatin (V), and dehydrodeguelin (VI) from the whole plant (mainly aerial part), pongamol (VII), rotenone (VIII), rotenolone (X), methylpongamol (XI), and a new flavonoid, [2S]-7-methoxy-8-(3-methoxy-3-methyl-but-1-enyl) flavanone (IX), from the root. Of these, rotenoids showed very strong nematocidal activity, while flavonoids and chalcones were weakly active or inactive. Rotenoids were found to be contained more in the root than in the aerial part.

• 日本生薬学会の論文
• 1989-03-20

著者

• Kiuchi Fumiyuki

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Kumar Vijaya

  Department Of Organic Chemistry Royal Institute Of Technology

• Tsuda Yoshisuke

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Kondo Kaoru

  School Of Medicine Kanazawa University

• CHEN XING

  Faculty of Pharmaceutical Sciences, Kanazawa University

• KUMAR VIJAYA

  Department of Chemistry, University of Peradeniya

関連論文

• In Vitro Leishmanicidal Activity of Benzophenanthridine Alkaloids from Bocconia pearcei and Related Compounds
• A Synthesis of 2-Substituted 2-Aminoethanol Derivatives Having Inhibitory Activity against Protein Kinase C
• Synthetic Studies on Glycosphingolipids from Protostomia Phyla: Synthesis of Glycosphingolipids from the Parasite Schistosoma mansoni
• Synthesis of Highly Deydrogenated Oxoerythrinan Alkaloids, Erytharbine and Crystamidine
• Effects of Long-Chain Fatty Acids and Fatty Alcohols on the Growth of Streptococcus mutans(Biological)
• Cytotoxic Principles of a Bangladeshi Crude Drug, Akond Mul (Roots of Calotropis gigantea L.)
• Localization and contents of paradisins, the most potent CYP3A4 inhibitors, in grapefruit Citrus paradisii and grapefruit juice
• STUDIES ON BIOLOGICALLY ACTIVE COMPOUNDS CONTAINED IN CHINESE MEDICINAL PLANTS USED AGAINST THE STAGNATION OF DISORDERED BLOOD
• Synthesis and Nematocidal Activity of Diarylnonanoids Related to Malabaricones
• Synthesis and Nematocidal Activity of Aralkyl- and Aralkenylamides Related to Piperamide on Second-Stage Larvae of Toxocara canis
• [2+2] Photocycloaddition Reaction of 5-Arylfuran-2,3-diones to Trimethylsilyloxyethylenes
• Dioxopyrrolines. LXI. Cycloaddition Reaction of 4-Benzoyl-5-ethoxycarbonyl-1-phenyl-1H-pyrrole-2,3-dione with 1,3-Dienes : Competitive Occurrence of Normal and Hetero Diels-Alder Reaction and Claisen Rearrangement of the Hetero Diels-Alder Product
• Total Synthesis of Homoerythrinan Alkaloids, Schelhammericine and 3-Epischelhammericine
• DNA Profiling of Acorus calamus Chemotypes Differing in Essential Oil Composition
• Acacia concinna Saponins. II. Structures of Monoterpenoid Glycosides in the Alkaline Hydrolysate of the Saponin Fraction
• Acacia concinna Saponins. I. Structures of Prosapogenols, Concinnosides A-F, Isolated from the Alkaline Hydrolysate of the Highly Polar Saponin Fraction
• Martefragin A, a Novel Indole alkaloid Isolated from Red Alga, Inhibits Lipid Peroxidation
• Chemical Transformation of Embelin through Dimerization during Preparation of a Decoction
• A New Diterpene Glycoside from Rabdosia Rubescens
• Dimerization of 2,5-Dihydroxybenzoquinones in Water
• Studies on Nepalese Crude Drugs. XXV. Phenolic Constituents of the Leaves of Didymocarpus leucocalyx C. B. CLARKE (Gesneriaceae)
• Studies toward Total Synthesis of Non-Aromatic Erythrinan Alkaloids. 7. Synthesis of Cocculolidine Skeleton
• General Method for Synthesis of Erythrinan and Homoerythrinan Alkaloids (1) : Synthesis of a Cycloerythrinan, as a Key Intermediate to Erythrina Alkaloids, by Pummerer-Type Reaction
• Thio-Sugars III. Radical Catalyzed Thione-Thiol Rearrangement of Cyclic Thionocarbonates on a Pyranose Ring : Formation of cis-Arranged Cyclic Thiolcarbonates
• Thio-Sugars. I. Radical-Promoted Thione-Thiol Rearrangement of Cyclic Thionocarbonates : Synthesis of 5-Thioglucose
• STEREOSELECTIVE SYNTHESIS OF AN ALKENOID-TYPE ERYTHRINAN ALKALOID, (±)-ERYTHRATIDINE
• Synthesis of Homoerythrinan Alkaloids of 1(2)-Alkene and 1,6-Diene Types : Total Synthesis of Comosine, Dihydroschelhammeridine, Schelhammeridine, and 3-Epischelhammeridine
• Oxidative Decarboxylation of Arylacetic Acids with Manganese(III)Acetate
• Chemistry of Oxo-Sugars. IV. Isomerization of 4-Oxoglycosides in a Pyridine Solution
• Chemistry of Oxo-Sugars. III. Transformations of 2- and 3-Oxoglycosides in a Pyridine Solution
• Genetic and chemical comparison of Boi (Sinomeni Caulis et Rhizoma) and Seifuto (Caulis Sinomenii)
• Regiocontrol in Pd-Catalyzed Allylic Substitution with P,N-Ligand
• 2-Chloro-N, N-dibenzoylaniline : a Selective N-Benzoylating Reagent
• Reaction of Cyclic Thioxocarbonates with Tributyltin Hydride(Organic,Chemical)
• Solvolytic Behaviors of O-Benzoyl, Cyclic O, O-Thionocarbonate, and O, S-Thiolcarbonate Groups in 3-O-Benzoyl-1,2-O-isopropylidene-α-D-glucofuranose Derivatives
• Thio-Sugars.IV.Synthesis of Carbohydrate 1, 3-Glycol (Six-Membered) Thionocarbonates and Their Attempted O-S Rearrangement
• Dioxopyrrolines. LX. Cycloaddition Reaction of 4-Benzoyl-5-ethoxycarbonyl-1-phenyl-1H-pyrrole-2,3-dione to Olefins : An Inverse-Electron-Demand Hetero Diels-Alder Reaction
• Localization and contents of paradisins, the most potent CYP3A4 inhibitors, in grapefruit Citrus paradisii and grapefruit juice
• PB8 APPROACHES TO SYNTHESES OF LINEATIN
• Analytical Studies on Poria cocos, II : The Relationship between the Triterpene Contents and the Color of the Sclerotium
• Identification of Major Constituents of a Saussurea gossypiphora Collected in Himalaya
• Nematocidal Principle(s) in Ulmi Pasta
• Screening of Crude Drugs Used in Bangladesh for Nematocidal Activity on the Larva of Toxocara canis
• Screening of Crude Drugs Used in Nepal for Nematocidal Activity on the Larva of Toxocara canis
• Nematocidal and Bursting Activities of Essential Oils on the Larvae to Toxocara canis
• Screening of Crude Drugs Used in Turkey for Nematocidal Activity on the Larva of Toxocara canis
• Screening of Crude Drugs Used in Sri Lanka for Nematocidal Activity on the Larva of Toxocara canis
• Nematocidal Activity of Some Anthelmintics, Traditional Medicines, and Spices by New Assay Method Using Larvae of Toxocara canis
• Sulfatides Inhibit Adhesion, Migration, and Invasion of Murine Melanoma B16F10 Cell Line in Vitro
• Studies on Crude Drugs Effective on Visceral Larva Migrans. VI : Identification of Nematocidal Principles in Tephrosia purpurea PERS.
• New Leishmanicidal Stilbenes from a Peruvian Folk Medicine, Lonchocarpus nicou
• Collagenase inhibitors from Viola yedoensis

もっと見る 閉じる

スポンサーリンク