Nematocidal Activity of Some Anthelmintics, Traditional Medicines, and Spices by New Assay Method Using Larvae of Toxocara canis
スポンサーリンク
概要
- 論文の詳細を見る
A new assay method for the screening of nematocidal drugs using the larva of dog roundworm, Toxocara canis, and the usefulness of this method are described. By using this method, the nematocidal activities of more than 40 commercially available spices were compared with the activities of known anthelmintic drugs and traditional medicines used for the anthelmintic purpose. Most of the anthelmintic drugs, which are used for matured parasites, were found to be only slightly or not at all active by this method, while, most spices, particularly their methanol extracts, were appreciably effective against the larva. The structures of nematocidal principles occurring in some of these spices were quite different from those of known anthelmintics, implying that this new assay method will lead to the discovery of a new type of anthelmintic drugs which directly kill the nematodes.
- 日本生薬学会の論文
- 1989-12-20
著者
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NAKAMURA Norio
Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts
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Kiuchi F
Graduate School Of Pharmaceutical Sciences Kyoto University
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Kikuchi F
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kiuchi Fumiyuki
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kiuchi Fumiyuki
Graduate School Of Pharmaceutical Sciences Kyoto University
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Nakamura Norifumi
President's Office Yoshitomi Pharmaceutical Industries Ltd.
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Nakamura Norihiro
Department Of Biological Sciences Graduate School Of Science Osaka University
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Kondo K
Nagoya City Univ. Nagoya Jpn
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Tsuda Yoshisuke
Faculty Of Pharmaceutical Sciences Kanazawa University
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KONDO KAORU
School of Medicine, Kanazawa university
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KIUHCI FUMIYUKI
Faculty of Pharmaceutical Sciences, Kanazawa University
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MIYASHIT NAOSHI
Faculty of Pharmaceutical Sciences, Kanazawa University
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NISHIZAWA SATOMI
Faculty of Pharmaceutical Sciences, Kanazawa University
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Miyashit Naoshi
Faculty Of Pharmaceutical Sciences Kanazawa University
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Miyashita Naoshi
Research And Development Division Hokuriku Seiyaku Co. Ltd.
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Nishizawa Satomi
Faculty Of Pharmaceutical Sciences Kanazawa University
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Kondo Kaoru
School Of Medicine Kanazawa University
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