Sensitivity, of Human Cancer Cells to the New Anticancer Ribo-nucleoside TAS-106 Is Correlated with Expression of Uridine-cytidine Kinase 2
スポンサーリンク
概要
- 論文の詳細を見る
- 2002-07-31
著者
-
岡部 尚文
日本ロシュ研究所
-
Kazuno Hiromi
Hanno Research Center Taiho Pharmaceutical Co. Ltd
-
Murakami Y
Hanno Research Center Taiho Pharmaceutical Co. Ltd
-
Fukushima M
Cancer Research Laboratory Taiho Pharmaceutical Co. Ltd.
-
Fukushima Masakazu
Taiho Pharmaceutical Co.
-
Matsuda A
Graduate School Of Pharmaceutical Sciences Hokkaido University
-
Matsuda A
Faculty Of Pharmaceutical Sciences Hokkaido University
-
Matsuda Akira
Graduate School of Pharmaceutical Sciences, Hokkaido University
-
SASAKI Takuma
Cancer Research Institute, Kanazawa University
-
Fujii M
Keio Univ. Tokyo Jpn
-
Okabe Hiroyuki
Nippon Roche Research Center
-
Okabe H
Hanno Research Center Taiho Pharmaceutical Co. Ltd.
-
岡部 尚文
日本ロシュ(株)研究所抗癌剤研究部
-
Yamada‐okabe H
Department Of Oncology Nippon Roche Research Center
-
Yamada Okabe
Pharmaceutical Research Department Chugai Pharmaceutical
-
Yamada Okabe
Pharmaceutical Research Department Iii Kamakura Research Laboratories
-
Yamada-okabe Hisafumi
Department Of Mycology Nippon Roche Research Center
-
Yamada-okabe Hisafumi
Dept. Of Mycology Nippon Roche Reserch Center
-
SHIMAMOTO Yuji
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
KOIZUMI Katsuhisa
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
OKABE Hiroyuki
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
MURAKAMI Yuko
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
NAKAGAWA Fumio
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
FUKUSHIMA Masakazu
Hanno Research Center, Taiho Pharmaceutical Co., Ltd.
-
Matsuda Akira
Department Of Pharmaceutical Sciences Faculty Of Pharmaceutical Sciences
-
Matsuda A
Hokkaido Univ. Sapporo
-
Matsuda Akira
The Department Of Internal Medicine Kin-ikyo Chuo Hospital
-
Shimamoto Yuji
Hanno Research Center Taiho Pharmaceutical Co. Ltd
-
Nakagawa Fumio
Hanno Research Center Taiho Pharmaceutical Co. Ltd.
-
Koizumi Kazuhisa
Hanno Research Center Taiho Pharmaceutical Co. Ltd
-
Fukushima Masakazu
Hanno Res. Center Taiho Pharmaceu. Co. Ltd.
-
Sasaki Takuma
Cancer Research Institute Kanazawa University
-
Sasaki Takuma
Department Of Experimental Therapeutics Cancer Research Insitute Kanazawa University
-
岡部 尚文
中外製薬(株)創薬企画推進部
-
Matsuda Akira
Graduate School Of Pharmaceutical Sciences Hokkaido University
-
MURAKAMI Yuko
Hanno Research Center, Taiho Pharmaceutical Co., Ltd
関連論文
- PP-1-293 通常型膵癌非治癒因子に関する臨床病理学的および分子生物学的検討
- Possible chemoresistance-related genes for gastric cancer detected by cDNA microarray
- Matrix Metalloproteinase Inhibitor, Marimastat, Decreases Peritoneal Spread of Gastric Carcinoma in Nude Mice
- The Citrus Flavonoid, Nobiletin, Inhibits Peritoneal Dissemination of Human Gastric Carcinoma in SCID Mice
- Nobiletin (citrus flavonoid) inhibits the production of MMP-9 and peritoneal metastasis of gastric carcinoma in SCID mice
- Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5-Fluorouracil
- Gene expression in colorectal cancer and in vitro chemosensitivity to 5-fluorouracil: A study of 88 surgical specimens
- Expression of Thymidylate Synthase in Human Non-small Cell Lung Cancer
- Antitumor Activity and Pharmacokinetics of TAS-106, 1-(3-C-Ethyny1-β-D-ribo-pentofuranosyl)cytosine
- Effects of Iprodione and Fludioxonil on Glycerol Synthesis and Hyphal Development in Candida albicans(Microbiology & Fermentation Technology)
- Interferon-α enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft models
- Collagen gel matrix assay as an in vitro chemosensitivity test for malignant astrocytic tumors
- P-253 DEVELOPMENT OF POTENT HISTAMINE H_3 AND/OR H_4 RECEPTOR ANTAGONISTS BY THE STEREOCHEMICAL DIVERSITY-ORIENTED CONFORMATIONAL RESTRICTION STRATEGY
- Conformational Analysis of the NMDA Receptor Antagonist (1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) Designed by a Novel Conformational Restriction Method Based on the Structural Feature of Cyclopronane Ring
- Deletion Mutants of Human Deoxycytidine Kinase mRNA in Cells Resistant to Antitumor Cytosine Nucleosides
- Synthesis of Conformationally Restricted Analogs of Baclofen, a Potent GABA_B Receptor Agonist, by the Introduction of a Cyclopropane Ring
- Nucleosides and Nucleotides. 186. Synthesis and Biological Activities of Pyrimidine Carbocyclic Nucleosides with a Hydroxyamino Group Instead of a Hydroxymethyl Group at the 4'-Position of the Sugar Moiety
- Isolation of Deoxycytidine Kinase from Ehrlich Carcinoma Cells by Affinity Chromatography Based on a Substrate Analog, 2'-C-Cyano-2'-deoxy-1-β-D-arabinofuranosyl-N^4-palmitoylcytosine
- New Neplanocin Anallogues. VIII. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A
- In Vitro and in Vivo Antitumor Activity of a Novel Nucleoside, 4'-Thio-2'-deoxy-2'-methylidenecytidine
- New Neplanocin Analogues. IX. A Practical Preparation of (6'R)-6'-C-Methylneplanocin A (RMNPA), a Potent Antiviral Agent, and the Determination of Its 6'-Configuration. Diastereoselective Deamination by Adenosine Deaminase
- UFT and S-1 for treatment of primary lung cancer
- Reactions between Hydroxyl-Radical-Induced 7,8-Dihydro-8-oxo-2'-deoxyguanosine Precursor and the Spin Trap α-Phenyl-N-tert-Butylnitrone
- Damage Induced by Hydroxyl Radicals Generated in the Hydration Layer of γ-Irradiated Frozen Aqueous Solution of DNA
- EXPRESSION OF TOXIC EFFECTS OF REACTIVE OXYGEN INTERMEDIATES IN CULTURED MAMMALIAN CELLS
- Sensitization of X-Irradiated Chinese Hamster V79 Cells by Derivatives of Pyrimidine Nucleosides
- Modification of the Repair of Potentially Lethal Damage in Plateau-Phase Chinese Hamster Cells by 2-Chlorodeoxyadenosine
- Saccharomyces cerevisiae キチン合成酵素の発現機構の解析 : 微生物
- S.cerevisiaeキチン合成酵素2の大量発現と部分精製 : 酵素
- Cytotoxic Principles of a Bangladeshi Crude Drug, Akond Mul (Roots of Calotropis gigantea L.)
- In vitro chemosensitivity test for human genito-urinary tumors using collagen gel matrix
- Relationship between Protein Levels and Gene Expression of Dihydropyrimidine Dehydrogenase in Human Tumor Cells during Growth in Culture and in Nude Mice
- Mutagenicity of 5-Formylcytosine, an Oxidation Product of 5-Methylcytosine, in DNA in Mammalian Cells
- Purealidins A-R, New Bromotyrosine Alkaloids from an Okinawan Marine Sponge Psammaplysilla purea
- ANTITUMOR ACTIVITY OF AQUEOUS EXTRACTS OF MARIRE ANIMALS
- EFFECT OF SERUM FROM MICE TREATED WITH ANTITUMOR POLYSACCHARIDE ON EXPRESSION OF CYTOTOXICITY BY MOUSE PERITONEAL MACROPHAGES
- Crystallographic Studies on Damaged DNAs : III. N^4-Methoxycytosine Can Form Both Watson-Crick Type and Wobbled Base Pairs in a B-Form Duplex^1
- Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma
- Antimalarial and Cytotoxic Activities of Bicyclo[6. 4. 0]dodecenones
- Sensitivity, of Human Cancer Cells to the New Anticancer Ribo-nucleoside TAS-106 Is Correlated with Expression of Uridine-cytidine Kinase 2
- Cellular and Biochemical Mechanisms of the Resistance of Human Cancer Cells to a New Anticancer Ribo-nucleoside, TAS-106
- Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides
- Heat-Assisted Stretching of Paraffin Sections on Hot Plate Weakens Immunoreactivity of Orotate Phosphoribosyltransferase
- Increased Supply of Boron to Swiss Chard Plants Did Not Affect the Level of Boron in a Cell Wall-Bound Form : A Possible Application to the Diagnosis of B Nutrition of Plants
- Reduced Activity of Anabolizing Enzymes in 5-Fluorouracil-resistant Human Stomach Cancer Cells
- 2C-20 Lethal Drug Interactions between Sorivudine and 5-Fluorouracil Caused by Suicidal Inactivation of Human Dihydropyrimidine Dehydrogenase by 5-(2-Bromovinyl) uracil
- Oral Administration of Uracil-Tegafur (UFT) Inhibits Liver Micrometastasis of Human Colon Cancer in an Orthotopic Nude Mouse Model and Its Early Detection System
- Excess Sludge Production and the Stable Operational Condition of a Submerged Membrane Activated Sludge Process
- Stable Operational Condition of Submerged Membrane Activated Sludge Process without Sludge Withdrawal
- THE EFFECT OF SLUDGE AGE ON DECOMPOSITION OF SLUDGE IN BATCH AEROBIC DIGESTION OF ACTIVATED SLUDGE ACCLIMATED TO GLUCOSE AND PEPTONE
- RADICAL DEOXYGENATION OF TERT-ALCOHLS IN 2'-BRANCHED-CHAIN SUGAR PYRIMIDINE NUCLEOSTDES : SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF 2'-DEOXY-2'(S)-METHYLCYTIDINE(Communications to the Editor)
- Graves' Hyperthyroidism Showing Transient Hypothyroidism during Interferon Therapy for Chronic Hepatitis Type C
- Treatment of Hyperthyroidism with a Small Single Daily Dose of Methimazole : A Prospective Long-Term Follow-Up Study
- Primary Aldosteronism with Bilateral Multiple Aldosterone-Producing Adrenal Adenomas
- Graves' Hyperthyroidism Following Transient Thyrotoxicosis during Interferon Therapy for Chronic Hepatitis Type C
- 抗体医薬の現状と展望
- LOCALIZATION OF BORON (B) HIGHER PLANT APOPLAST
- (1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PRDC), a New Class of NMDA-Receptor Antagonist: Molecular Design by a Novel Conformational Restriction Strategy
- Genomics を用いた創薬研究 : 新規標的分子の探索, High-throughput screening, 及び診断への応用(植物保護とバイオテクノロジー : バイオテクノロジー技術の農薬研究への応用)
- SI5 Genomics を用いた創薬研究 : 新規標的分子の探索、 high-throughput screening 及び診断への応用
- The gene cloning and characterization of 1, 3-β-glucan synthase from Candida albicans
- Charaterization of Chitin Synthase 2 of Saccharomyces cerevisiae II: Both Full Size and Processed Enzymes Are Active for Chitin Synthesis
- Total Synthesis of (±)-Acetomycin and Design of Esterase-Resistant Analogs
- P-530 Synthetic Study of the Stable Analog of Chitin Synthase Inhibitors, Guanofosfosins
- Mycoleptodiscus terrestris from black pepper roots in the Dominican Republic
- Fungi associated with roots and fruits of black peppers in the Dominican Republic
- A defucosylated anti-CD317 antibody exhibited enhanced antibody-dependent cellular cytotoxicity against primary myeloma cells in the presence of effectors from patients
- Cytotoxicity of Synthetic Estrogen and Related Compounds in Various Tumor-Derived Cells
- Inverse Correlation between mRNA EXpression of Plasminogen Activator Inhibitor-2 and Lymph Node Metastasis in Human Breast Cancer
- A New Eudesmane Sesquiterpene from the Fruit Body of Lactarius laeticolorus
- Total Synthesis and the Three-Dimensional Structure-Activity Relationship Study of Tripeptide Antibiotic Belactosin A, a Potent Proteasome Inhibitor
- A new disulfide-linked dimer of a single-chain antibody fragment against human CD47 induces apoptosis in lymphoid malignant cells via the hypoxia inducible factor-1α pathway
- Antitumor activity of sugar-modified cytosine nucleosides
- 酵母のキチン合成酵素の機能と性質
- A New Eudesmane Sesquiterpene from the Fruit Body oiLactarius laeticolorus
- ANTITUMOR ACTIVITY OF SUGAR-MODIFIED CYTOSINE NUCLEOSIDES
- Characterization of Chitin Synthase 2 of Saccharomyces cerevisiae II: Both Full Size and Processed Enzymes Are Active for Chitin Synthesis.