DANSHENOLS A AND B, NEW ALDOSE REDUCTASE INHIBITORS FROM THE ROOT OF SALVIA MILTIORHIZA BUNGE

スポンサーリンク

概要

• 論文の詳細を見る

• Two new abietane-type diterpenoids, danshenols A (1) and B (2), were isolated from an MeOH extract of Salvia miltiorhiza BUNGE, and their structures determined by chemical and spectroscopic methods including the 2D NMR technique. Danshenol A (1) showed strong inhibitory activity against aldose reductase isolated from the eye lens of rats.

• 公益社団法人日本薬学会の論文
• 1997-03-15

著者

• Kadota S

  富山大学和漢医薬学総合研究所

• Kadota S

  Institute Of Natural Medicine University Of Toyama

• TEZUKA Yasuhiro

  Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University

• Namba Ttuneo

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Namba Tsuneo

  富山医科薬科大学 生薬

• Namba Tsuneo

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Nagaoka Takema

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Nagaoka Takema

  富山医科薬科大学和漢薬研究所

• Basnet Purusotam

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Tezuka Yasuhiro

  Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University

• KADOTA Shigetoshi

  Research Institute of Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceu

• KASIMU Rena

  Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmace

• Basnet Purusotam

  富山医科薬科大学和漢薬研究所

• Basnet Purusotam

  Research Center For Ethnomedicines Institute Of Natural Medicine Toyama Medical And Pharmaceutical U

• Kadota Shigetoshi

  Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University

• Kasimu Rena

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Basnet P

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Namba Tsuneo

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicine) Toyama Medical And Pharmaceut

• Namba Tsuneo

  Research Institute For Wakan-yaku (oriental Medicine) Toyama Medical And Pharmaceutical University

• 門田 重利

  Institute of Natural Medicine, University of Toyama

関連論文

• Investigation on traditional medicine at Phu Quoc Island and Ninh Thuan Province in Vietnam
• Hypouricemic Effects of Acacetin and 4,5-O-Dicaffeoylquinic Acid Methyl Ester on Serum Uric Acid Levels in Potassium Oxonate-Pretreated Rats(Pharmacology)
• Xanthine Oxidase Inhibitors from the Heartwood of Vietnamese Caesalpinia sappan
• Xanthine Oxidase Inhibitory Activity of Vietnamese Medicinal Plants(Pharmacognosy)
• Metabolism-dependent inhibition of CYP3A4 and CYP2D6 by extracts from 26 herbal medicines
• Inhibition of human liver microsomal CYP3A4 and CYP2D6 by extracts from 78 herbal medicines
• Traditional medicine of Madura island in Indonesia
• Panduratins D-I, Novel Secondary Metabolites from Rhizomes of Boesenbergia pandurata
• New prenylated flavones from Artocarpus champeden, and their antimalarial activity in vitro
• Constituents of Boesenbergia pandurata and Their cytotoxicity against PANC-1 Cells under Nutrient Deprived Condition(The 24th Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU)
• The healing art of traditional medicines in Myanmar
• Antimalarial Activity of Cassane- and Norcassane-Type Diterpenes from Caesalpinia crista and Their Structure-Activity Relationship(Pharmacology)
• Constituents of Caesalpinia crista from Indonesia
• Methyl Migrated Cassane-Type Furanoditerpenes of Caesalpinia crista from Myanmar
• Nitric Oxide (NO) Production Inhibitory Constituents of Tabebuia avellanedae from Brazil
• New Cassane-Type Diterpenes of Caesalpinia crista from Myanmar
• Inhibition of NO Production by Highly-Oxygenated Diterpenes of Orthosiphon stamineus and Their Structure-Activity Relationship
• Highly-Oxygenated Tsopimarane-Type Diterpenes from Orthosiphon stamineus of Indonesia and Their Nitric Oxide Inhibitory Activity
• Antiproliferative Activity of the Netherlands Propolis and Active Constituents
• Constituents of the Vietnamese Medicinal Plant Orthosiphon stamineus
• Quadranosides VI-XI, Six New Triterpene Glucosides from the Seeds of Combretum quadrangulare
• Prevention of Growth and Metastasis of Murine Melanoma through Enhanced Natural-Killer Cytotoxicity by Fatty Acid-Conjugate of Protopanaxatriol
• Antiproliferative Activity of Vietnamese Medicinal Plants
• Antiproliferative Activity of Diarylheptanoids from the Seeds of Alpinia blepharocalyx
• Inhibitory Mechanisims of Glycoprotein Fraction Fraction Derived from Miscanthus Sinensis for the Immediate Phase Response of an IgE-mediated Cutaneous Reaction.
• Hepatoprotective Effect of Combretum quadrangulare and Its Constitutents
• Methyl Quadrangularates A-D and Related Triterpenes from Combretum quadrangulare
• Pharmacokinetics of Ginsenoside Deglycosylated by Intestinal Bacteria and Its Transformation to Biologically Active Fatty Acid Esters
• Effect of Spikelets of Miscanthus Sinensis on IgE-Mediated Biphasic cutaneous Reaction in Mice.
• Inhibitory Mechanisms of Glycoprotein Fraction Derived from Miscanthus sinensis for the Immediate Phase Response of an IgE-Mediated Cutaneous Reaction
• Anti-metastatic and immunomodulating Properties of the Water Extract from Celosia argentea Seeds
• Synthesis and Characterization of a Carbene-Generating Biotinylated Lactosylceramide Analog as a Novel Chromogenic Photoprobe for GM_3 Synthase
• Mechanism-Based Inactivation of Human Liver Microsomal CYP3A4 by Rutaecarpine and Limonin from Evodia Fruit Extract
• Sulfation of Environmental Estrogens by Cytosolic Human Sulfotransferases
• Buds of Baccharis dracunculifolia : potent source of biologically active caffeoylquinic acids and labdane-type diterpenes of Brazilian propolis
• Inhibitory effect of Kampo medicines on bone resorption in vitro and preventive effect on bone loss in vivo
• Synthesis and antihepatotoxic and antiproliferative activities of di- and tri-O-caffeoylquinic acid derivatives
• Conversion of aconitine lipoaconitine by human intestinal bacteria and their antinociceptive effects in mice
• Prophylactic efficacy of traditional herbal medicines against recurrent herpes simplex virus type 1 infection from latently infected ganglia in mice
• Assay for Antiviral Activity of Herbal Extracts Using Their Absorbed Sera
• Effect of Berberine on Bone Mineral Density in SAMP6 as a Senile Osteoporosis Model(Pharmacognosy)
• The Effect of Kampo Formulae on Bone Resorption in Vitro and in Vivo. II. Detailed Study of Berberine
• The Effect of Kampo Formulae on Bone Resorption in Vitro and in Vivo. I. Active Constituents of Tsu-Kan-gan
• Antiosteoporotic Activity of the Stems of Sambucus sieboldiana
• Effect of Japanese Angelica Root Extract on Pentobarbital-Induced Sleep in Group-Housed and Socially Isolated Mice:Evidence for the Central Action
• STRUCTURE OF SCOPARIC ACID A, A NEW LABDANE-TYPE DITERPENOID FROM A PARAGUAYAN CRUDE DRUG "TYPYCHA KURATU" (SCOPARIA DULCIS L.)(Communications to the Editor)
• PA67 STRUCTURE OF BOERAVINONE A, B, AND C. NEW ROTENOID ANALOGUES FROM BOERHAAVIA DIFFUSA LINN
• Studies on Metabolites of Mycoparasitic Fungi. V. Ion-Spary Ionization Mass Spectrometric Analysis of Trichokonin-II, a Peptaibol Mixture Obtained from the Culture Broth of Trichoderma koningii
• Cytochrome P450 2D6 (CYP2D6) Inhibitory Constituents of Catharanthus roseus(Pharmacognosy)
• Mechanism-Based Inhibition of CYP3A4 by Constituents of Zingiber aromaticum(Pharmacognosy)
• Constituents of Zingiber aromaticum and Their CYP3A4 and CYP2D6 Inhibitory Activity
• A Combination of Soft-Shell Turtle Powder and Essential Oil of a Unicellular Chorophyte Prevents Bone Loss and Decreased Bone Strength in Ovariectomized Rats(Pharmacognosy)
• Antiosteoporotic Activity of the Water Extract of Dioscorea spongiosa (Pharmacognosy)
• Antiproliferative Activity of Cardenolides Isolated from Streptocaulon juventas(Pharmacognosy)
• Wild Ginseng Grows in Myanmar
• Inhibitory Effect of Diarylheptanoids on Nitric Oxide Production in Activated Murine Macrophages
• Hepatoprotective Principles of Swertia japonica MAKINO on D-Galactosamine/Lipopolysaccharide-Induced Liver Injury in Mice
• Hepatoprotective Effect of Hovenia dulcis THUNB. on Experimental Liver Injuries Induced by Carbon Tetrachloride or D-Galactosamine : Lipopolysaccharide
• TETRAHYDROSWERTIANOLIN : A POTENT HEPATOPROTECTIVE AGENT FROM SWERTIA JAPONICA MAKINO
• Four Di-O-caffeoyl Quinic Acid Derivatives from Propolis. Potent Hepatoprotective Activity in Experimental Liver Injury Models
• POTENT ANTIHEPATOTOXIC ACTIVITY OF DICAFFEOYL QUINIC ACIDS FROM PROPOLIS
• Protective Effect of Celosian, an Acidic Polysaccharide, on Chemically and Immunologically Induced Liver Injuries
• Apocynins A-D : New Phenylpropanoid-substituted Flavan-3-ols Isolated from Leaves of Apocynum venetum (Luobuma-Ye)
• Antioxidative Effects of Phenylethanoids from Cistanche deserticola
• Comparative Study of Seventeen Salvia Plants : Aldose Reductase Inhibitory Activity of Water and MeOH Extracts and Liquid Chromatography-Mass Spectrometry (LC-MS) Analysis of Water Extracts
• Constituents of Roots of Salvia deserta SCHANG. (Xinjiang-Danshen)
• Processing of Nux Vomica. VII. Antinociceptive Effects of Crude Alkaloids from the Processed and Unprocessed Seeds of Strychnos nux-vomica in Mice
• Processing of Nux Vomica. IV : A Comparison of Cytotoxicity of Nine Alkaloids from Processed Seeds of Strychnos nux-vomica on Tumor Cell Lines
• Effects of Long-Chain Fatty Acids and Fatty Alcohols on the Growth of Streptococcus mutans(Biological)
• New 2,5-Bis-aryl-3,4-dimethyltetrahydrofuran Lignans from the Aril of Myristica fragrans(Pharmacognosy,Chemical)
• Highly Selective Antibacterial Activity of Novel Alkyl Quinolone Alkaloids from a Chinese Herbal Medicine, Gosyuyu (Wu - Chu - Yu), against Helicobacter pylori In Vitro
• Secoisolariciresinol, a Potent Hypoglycemic Agent from the Wood of Taxus yunnanensis
• Inhibitory effect of constituents of Bu-Shen-Jian-Gu-Tang on osteoclast-like cell formation
• Inhibitory Effects of Caffeic Acid Phenethyl Ester Analogues on Experimental Lung Metastasis of Murine Colon 26-L5 Carcinoma Cells
• Caffeic Acid Phenethyl Ester (CAPE) Analogues: Potent Nitric Oxide Inhibitors from the Netherlands Propolis
• Origin of"Koku-oren(黒黄連)", One of the Shosoin Items
• Biological Evaluation and LC-MS Analysis of Propolis from Brazil, Peru, China and the Netherlands : 天然物化学
• Prolyl Endopeptidase Inhibitors from the Underground Part of Rhodiola sacra S. H. Fu
• Antibacterial activity of traditional medicines and an active constituent lupulone from Humulus lupulus against Helicobacter pylori
• Constituents of Water Extract of Brazilian Propolis, Their Biological Properties and Botanical Origin
• Synthesis of a Biologically Active Fluorescent Derivative of GM1,a Main Ginseng Saponin Metabolite Formed by Intestinal Bacteria
• Prolyl Endopeptidase Inhibitors from the Underground Part of Rhodiola sachalinensis
• Isolation of Two New Flavonoids and Antiproliferative Activity of Chinese Propolis
• Michael-Type Addition of Illudin S, a Toxic Substance from Lampteromyces japonicus, with Cysteine and Cysteine-Containing Peptides in Vitro
• Hepatoportective Constituents of the Seeds of Combretum quadrangulare
• Hepatoprotective Constituents from MeOH extract of Seeds of Combretum quadrangulare : 天然物化学
• Effect of Depignentation for 3,4-di-O-Caffeoylquinic Acid Guided by Tyrosinase Inhibitory Activity from Conyza filaginoides
• A New Triterpene Ester from Eriobotrya japonica
• Aodose Reductase Inhibitory Constituents of the Root of Salvia miltiorhiza BUNGE
• DANSHENOLS A AND B, NEW ALDOSE REDUCTASE INHIBITORS FROM THE ROOT OF SALVIA MILTIORHIZA BUNGE
• Studies on the Constituents of Scutellaria Species. XVIII. Structures of Neoclerodane-Type Diterpenoids from the Whole Herb of Scutellaria rivularis WALL.
• STRUCTURES OF TRIPTOFORDININE A-1 AND A-2 DETERMINED BY TWO-DIMENSIONAL NMR SPECTROSCOPY. HIGHLY ESTERIFIED SESQUITERPENE ALKALOIDS FROM TRIPTERYGIUM WILFORDII HOOK FIL. VAR. REGELII MAKINO(Communications to the Editor)
• Neuroprotective Effects of Constituents of the Oriental Crude Drugs,Rhodiola sacra, R. sachalinensis and Tokaku-joki-to, against Beta-amyloid Toxicity, Oxidative Stress and Apoptosis
• Constituents of the Underground Parts of Glehnia littoralis
• Effect of Mirabilitum in Formularization: Change of Prolyl Endopeptidase Inhibitory Activity and of Constituents Using the Preparation Method of Tokaku-joki-to(桃核承気湯, Persia and Rhubarb Combination)
• Quality evaluation of Propolis. 1. A comparative study on radical scavenging effects of Propolis and Vespae Nidus (露蜂房)
• Processing of Nux Vomica. IV. : A Comparison of Cytotoxicity of Nine Alkaloids from Processed Seeds of Strychnos nux-vomica on Tumor Cell Lines
• A Comparative Study of Alkaloidal Constituents in Corydalis decumbens Tubers by High Performance Liquid Chromatography
• Origin of"Koku-oren(黒黄連)", One of the Shosoin Items
• Prolyl Endopeptidase Inhibitory Activity of Fourteen Kampo Formulas and Inhibitory Constituents of Tokaku-joki-to(桃核承気湯)

もっと見る 閉じる

スポンサーリンク