A Combination of Soft-Shell Turtle Powder and Essential Oil of a Unicellular Chorophyte Prevents Bone Loss and Decreased Bone Strength in Ovariectomized Rats(Pharmacognosy)
スポンサーリンク
概要
- 論文の詳細を見る
The effects of soft-shell turtle (Trionyx sinensis) powder (SST) on the proximal tibiae of ovariectomized (OVX) rats were investigated using peripheral quantitative computed tomography (pQCT) and examination of serum biochemical markers. Considering the relationship between the antioxidative property and antiosteoporotic activity, the synergistic effects of a mixture of SST and essential oil of the microalgae Haematococcus pluvialis (OHP) with strong antioxidant activity were also examined. Oral administration of SST (100, 200 mg/kg) or a mixture of SST (100, 200 mg/kg) and OHP (13, 26 mg/kg) three times weekly prevented the decrease in bone mineral content (BMC) in total bone, BMC and bone mineral density (BMD) in cortical bone, and bone strength indices induced by ovariectomy in a dose-dependent manner without uterine side effects. However, OHP alone showed no significant effects.
- 公益社団法人日本薬学会の論文
- 2005-02-01
著者
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KADOTA Shigetoshi
Institute of Natural Medicine, University of Toyama
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TEZUKA Yasuhiro
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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門田 重利
富山大学和漢医薬学総合研究所 化学応用部門
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Kadota S
富山大学和漢医薬学総合研究所
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門田 重利
冨山大学和漢医薬学総合研究所
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門田 重利
富山大学和漢医薬学総合研究所資源開発部門化学応用分野
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手塚 康弘
富山大学和漢医薬学総合研究所化学応用分野
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KALAUNI Surya
Institute of Natural Medicine, University of Toyama
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UEDA Jun-ya
Institute of Natural Medicine, University of Toyama
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Kadota Shigetoshi
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
富山大学和漢医薬学総合研究所 化学応用分野
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Kadota S
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
Univ. Toyama Toyama Jpn
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Kadota Shigetoshi
インドネシア
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上田 順市
放射線医学総合研
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Ueda Junya
Institute Of Natural Medicine University Of Toyama
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Shi Liying
Div. Of Natural Products Chemistry Inst. Of Natural Medicine Toyama Medical And Pharmaceutical Univ.
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Shi Liying
Division Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceutic
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Shi Liying
Institute Of Natural Medicine University Of Toyama
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Ueda J
National Institute Of Radiological Sciences
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Matsumoto Kinzo
Division Of Medicinal Pharmacology Institute Of Natural Medicine Toyama Medical And Pharmaceutical U
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門田 重利
Institute Of Natural Medicine University Of Toyama
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Yin Jun
Jilin Architectural and Civil Engineering Institute
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Tezuka Yasuhiro
Univ. Toyama Toyama Jpn
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Tezuka Yasuhiro
Institute Of Natural Medicine Univeristy Of Toyama
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Tezuka Yasuhiro
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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Tezuka Y
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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YIN Jun
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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MATSUSHIGE Katsumichi
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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Kadota S
Research Institute For Wakan-yaku(traditional Sino-japanese Medicines) Toyama Medical And Pharmaceut
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Kadota Shigetoshi
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Matsushige Katsumichi
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Matsushige Katsumichi
Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu
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Kalauni S
Institute Of Natural Medicine University Of Toyama
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Kadota S
Toyama Medical And Pharamaceutical Univ. Toyama Jpn
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Yin Jun
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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門田 重利
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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Tezuka Yasuhiro
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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手塚 康弘
Institute Of Natural Medicine University Of Toyama
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門田 重利
Institute of Natural Medicine, University of Toyama
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