Nitric Oxide (NO) Production Inhibitory Constituents of Tabebuia avellanedae from Brazil
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概要
- 論文の詳細を見る
From the water extract of Brazilian Tabebuia avellanedae, two new iridoids (1, 2) and a new phenylethanoid glycoside (3) have been isolated together with twelve known compounds (4-15). Their structures were determined based on the spectroscopic data. The isolated compounds inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-activated macrophage-like J774.1 cells. Compounds 1, 3, 10, 11, and 12 showed inhibitory activities more potent (IC_<50>, 13.8-26.1μg/ml) than a positive control N^G-monomethyl-L-arginine (L-NMMA; IC_<50>, 27.4μg/ml).
- 社団法人日本薬学会の論文
- 2005-06-01
著者
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AWALE Suresh
Institute of Natural Medicine, University of Toyama
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KADOTA Shigetoshi
Institute of Natural Medicine, University of Toyama
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TEZUKA Yasuhiro
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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門田 重利
富山大学和漢医薬学総合研究所 化学応用部門
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Kadota S
富山大学和漢医薬学総合研究所
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門田 重利
冨山大学和漢医薬学総合研究所
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門田 重利
富山大学和漢医薬学総合研究所資源開発部門化学応用分野
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手塚 康弘
富山大学和漢医薬学総合研究所化学応用分野
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Awale Suresh
インドネシア
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Awale Suresh
富山大学和漢医薬学総合研究所
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Awale Suresh
Institute Of National Medicine Toyama Medical And Pharmaceutical University
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KALAUNI Surya
Institute of Natural Medicine, University of Toyama
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UEDA Jun-ya
Institute of Natural Medicine, University of Toyama
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KAWAKAMI Tsukasa
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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UEDA Junya
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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TANAKA Ken
National Police Agency
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Kadota Shigetoshi
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
富山大学和漢医薬学総合研究所 化学応用分野
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Kadota S
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
Univ. Toyama Toyama Jpn
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Kadota Shigetoshi
インドネシア
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Tominaga Kazunari
Department Of Gastroenterology Osaka City University Graduate School Of Medicine
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上田 順市
放射線医学総合研
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Awale Suresh
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Ueda Junya
Institute Of Natural Medicine University Of Toyama
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Tran Kim
National University Hochiminh City
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Tominaga K
Osaka City Univ. Osaka Jpn
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Ueda J
National Institute Of Radiological Sciences
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門田 重利
Institute Of Natural Medicine University Of Toyama
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Tezuka Yasuhiro
Univ. Toyama Toyama Jpn
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Tezuka Yasuhiro
Institute Of Natural Medicine Univeristy Of Toyama
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Tezuka Yasuhiro
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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Torii K
Department Of Nuclear Medicine Graduate School Of Medicine Osaka City University
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Tezuka Y
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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Kadota S
Research Institute For Wakan-yaku(traditional Sino-japanese Medicines) Toyama Medical And Pharmaceut
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Kadota Shigetoshi
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Kalauni S
Institute Of Natural Medicine University Of Toyama
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Kawakami Tsukasa
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Kadota S
Toyama Medical And Pharamaceutical Univ. Toyama Jpn
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門田 重利
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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Tezuka Yasuhiro
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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手塚 康弘
Institute Of Natural Medicine University Of Toyama
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門田 重利
Institute of Natural Medicine, University of Toyama
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