Antiallergic Activity of Aqueous Extracts and Constituents of Taxus yunnanensis(Pharmacognosy)

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概要

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• The H_2O, H_2O/MeOH (1:1) extracts from the wood of Taxus yunnanensis showed a remarkable inhibitory effect on induced histamine release from the human basophilic cell line, KU812. The eleven constituents purified from the wood extracts of Taxus yunnanensis were tested by an in vitro histamine release inhibition assay. Among them, secoisolarciresinol and taxiresinol were found to show inhibitory activities. A new neolignan, 2-[2-hydroxy-5-(3-hydroxypropyl)-3-methoxyphenyl]-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol, was isolated from the wood of Taxus yunnanensis.

• 公益社団法人日本薬学会の論文
• 2006-11-01

著者

• KADOTA Shigetoshi

  Institute of Natural Medicine, University of Toyama

• Kadota Shigetoshi

  Institute Of Natural Medicine University Of Toyama

• Kadota Shigetoshi

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Koyama Junko

  Kobe Pharmaceutical University

• Koyama J

  Kobe Pharmaceutical University

• Simamura Eriko

  Department Of Molecular And Cell Structural Science Kanazawa Medical University

• MORITA Izumi

  Kobe Pharmaceutical University

• KOBAYASHI Norihiro

  Kobe Pharmaceutical University

• HIRAI Keiichi

  Department of Molecular and Cell Structural Science, Kanazawa Medical University

• NOBUKAWA Takahiro

  Medical Research Institute, Kanazawa Medical University

• Nobukawa Takahiro

  Medical Research Institute Kanazawa Medical University

• Hirai Keiichi

  Department Of Molecular And Cell Structural Science Kanazawa Medical University

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