Antiproliferative Activity of Vietnamese Medicinal Plants
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概要
- 論文の詳細を見る
Methanol, methanol-water (1:1) and water extracts were prepared from seventy-seven Vietnamese medicinal plants and tested for their antiproliferative activities against human HT-1080 fibrosarcoma cells. Among them, fifteen extracts including seven methanol extracts of Caesalpinia sappan, Catharanthus roseus, Coscinium fenestratum, Eurycoma longifolia, Hydnophytum formicarum and Streptocaulon juventas (collected at two areas),six methanol-water (1:1) extracts of Cae. sappan, Cat. roseus, Co. fenestratum, H. formicarum and S. juventas (at two areas), and two water extracts of Cae. sappan and S. juventas exhibited antiproliferative activities in a concentration-dependent manner. Their antiproliferative activities against human cervix HeLa adenocarcinoma,human lung A549 adenocarcinoma, murine colon 26-L5 carcinoma, murine Lewis lung carcinoma (LLC) and murine B16-BL6 melanoma cells were then examined. Co. fenestratum showed selective activity against lung carcinoma and/or lung metastatic cell lines, A549, LLC and B16-BL6, while H. formicarum and S.juventas showed selective activity against human tumor cell lines, HeLa and A549. Characteristic morphological change and DNA fragmentation indicated the antiproliferative activity to be due to the induction of apoptosis.
- 社団法人日本薬学会の論文
- 2002-06-01
著者
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TRAN Quan
National University-Hochiminh City, Hochiminh City
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KADOTA Shigetoshi
Institute of Natural Medicine, University of Toyama
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TEZUKA Yasuhiro
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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TRAN Quan
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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SAIKI Ikuo
Institute of Natural Medicine, University of Toyama
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BANSKOTA Arjun
Institute of Natural Medicine, University of Toyama
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UEDA Jun-ya
Institute of Natural Medicine, University of Toyama
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Banskota A
Institute Of Natural Medicine University Of Toyama
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Banskota Arjun
富山医科薬科大学和漢薬研究所
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Banskota Arjun
Institute Of National Medicine Toyama Medical And Pharmaceutical University
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Tran Quan
National University-hochiminh City Hochiminh City
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Saiki Ikuo
富山大学 薬学研究科応用薬理学
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Saiki I
Division Of Pathogenic Biochemistry Institute Of Natural Medicine University Of Toyama
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TRAN Qui
National University-Hochiminh City
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HARIMAYA Yuko
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University
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SAIKI Ikuo
Division of Pathogenic Biochemistry, Institute of Natural Medicine, University of Toyama
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Kadota Shigetoshi
富山大学和漢医薬学総合研究所 化学応用分野
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Kadota S
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
インドネシア
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上田 順市
放射線医学総合研
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Saiki Ikuo
Division Of Pathogenic Biochemistry Institute Of Natural Medicine University Of Toyama
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Saiki I
Institute Of Natural Medicine University Of Toyama
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Ueda Junya
Institute Of Natural Medicine University Of Toyama
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Tran Quan
National University
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Tran Q
National University - Hochiminh City
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Tran Qui
National University - Hochiminh City
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Saiki Ikuo
Department Of Pathological Biochemistry Institute Of Natural Medicine Toyama Medical And Pharmaceuti
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Banskota A
富山医科薬科大学和漢薬研究所化学応用部門
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Banskota Arjun
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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Tran Quan
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Ueda J
National Institute Of Radiological Sciences
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門田 重利
Institute Of Natural Medicine University Of Toyama
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Tezuka Yasuhiro
Institute Of Natural Medicine Univeristy Of Toyama
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Saiki Ikuo
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Kadota Shigetoshi
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Kalauni S
Institute Of Natural Medicine University Of Toyama
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Kadota S
Toyama Medical And Pharamaceutical Univ. Toyama Jpn
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Harimaya Yuko
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Banskota Arjun
Department Of Natural Products Chemistry Institute Of Natural Medicine Toyama Medical And Pharmaceut
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Saiki Ikuo
Institute Of Immunological Science Hokkaido University
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手塚 康弘
Institute Of Natural Medicine University Of Toyama
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Banskota Arjun
Institute For Marine Biosciences National Research Council
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門田 重利
Institute of Natural Medicine, University of Toyama
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