Mechanical Hypersensitivity and Alterations in Cutaneous Nerve Fibers in a Mouse Model of Skin Cancer Pain
スポンサーリンク
概要
- 論文の詳細を見る
Melanoma inoculation induced marked mechanical allodynia and hyperalgesia in the periphery of the melanoma mass in mice from about day 10 post-inoculation. In the middle of the tumor, there were slight hyperalgesia and response disappearance in the early and late phases, respectively. PGP9.5-like immunoreactivities increased in the epidermis of the periphery of the tumor and disappeared from the dermis of the middle on day 18 post-inoculation, without apparent alterations on day 10. When using this pain model, one should consider the tumor site-dependent responses.
- 社団法人 日本薬理学会の論文
- 2003-02-01
著者
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ANDOH Tsugunobu
Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, Univers
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NOJIMA Hiroshi
Department of Pharmacology, School of Pharmaceutical Sciences, Ohu University
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KURAISHI Yasushi
Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, Univers
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Nagai Hiroichi
富山医科薬科大学和漢薬研究所
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SAIKI Ikuo
Department of Pathogenic Biochemistry, Institute of Natural Medicine, Toyama Medical and Pharmaceuti
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Saiki Ikuo
富山大学 薬学研究科応用薬理学
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Saiki I
Division Of Pathogenic Biochemistry Institute Of Natural Medicine University Of Toyama
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Andoh Tsugunobu
Department Of Applied Pharmacology Graduate School Of Medicine And Pharmaceutical Sciences Universit
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SAIKI Ikuo
Division of Pathogenic Biochemistry, Institute of Natural Medicine, University of Toyama
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Kuraishi Yasushi
Department Of Applied Pharmacology Graduate School Of Medical And Pharmaceutical Science University
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Kuraishi Yasushi
Department Of Applied Pharmacology Graduate School Of Medicine And Pharmaceutical Sciences Universit
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Saiki Ikuo
Division Of Pathogenic Biochemistry Institute Of Natural Medicine University Of Toyama
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Saiki I
Institute Of Natural Medicine University Of Toyama
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Nojima H
Department Of Pharmacology School Of Pharmaceutical Sciences Ohu University
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IIDA Yuko
Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, Univers
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Murata Jun
Department Of Pathological Biochemistry Institute Of Natural Medicine Toyama Medical And Pharmaceuti
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Nagai Hiroichi
岐阜薬科大学 薬理
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Zhang H‐w
State Key Lab. Magnetism Chinese Acad. Sci. Beijing Chn
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Zhang Hong-wei
Department Of Applied Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceuti
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Zhang Hong
富山医科薬科大学 薬 2薬剤薬理
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Murata Jun
Department Of Physiology Institute Of Health Sciences Hiroshima University Faculty Of Medicine
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Nojima Hiroshi
Department Of Applied Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceuti
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Ida Yuko
Department Of Applied Pharmacology Graduate School Of Medicine And Pharmaceutical Sciences Universit
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Saiki Ikuo
Department Of Pathological Biochemistry Institute Of Natural Medicine Toyama Medical And Pharmaceuti
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Nemoto Hideo
Laboratory Of Medical Chemistry Graduate School Of Medicine And Pharmaceutical Sciences University O
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Iida Yasuhiko
Department Of Bioimaging Medical Sciences Gunma University
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Iida Yasuhiko
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Sciences Kyoto University
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Saiki Ikuo
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Andoh Tsugunobu
Department Of Applied Pharmacology Faculty Of Pharmaceu Tical Sciences
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Nagai Hiroichi
Department Of Pharmacology School Of Pharmaceutical Sciences Ohu University
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Nojima Hiroshi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Ohu University
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Murata Jun
Department Of Applied Physics Faculty Of Engineering University Of Tokyo:presently At Musashi Works
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Nojima H
Department Of Applied Pharmacology Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceuti
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Nishida Hiroyuki
Department Of Pharmacology Gifu Pharmaceutical University
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Kuraishi Yasushi
Department Of Applied Pharmacology Faculty Of Pharmaceu Tical Sciences
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Saiki Ikuo
Department Of Pathogenic Biochemistry Institute Of Natural Medicine Toyama Medical And Pharmaceutica
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Kuraishi Yasushi
Department Of Applide Biochemistry Research Institute For Wakan-yaku Toyama Toyama Medical And Pharm
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Saiki Ikuo
Department Of Bioscience Institute Of Natural Medicine Toyama University
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Nojima Hiroshi
Laboratory Of Medical Chemistry Graduate School Of Medicine And Pharmaceutical Sciences University O
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Nemoto Hideo
Laboratory Of Medical Chemistry Graduate School Of Medicine And Pharmaceutical Sciences University O
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Andoh Tsugunobu
Department Of Applied Pharmacology Graduate School Of Medicine And Pharmaceutical Sciences Universit
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Iida Yuko
Department of Applied Pharmacology, Faculty of Pharmaceutical Sciences
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