<Abstract of annual report>Genotoxicity of a Variety of Azobenzene and Aminoazobenzene Compounds in the Hepatocyte/DNA Repair Test and the Salmonella/Mutagenicity Test.
スポンサーリンク
概要
著者
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SUGIE Shigeyuki
Department of Oncologic Pathology, Kanazawa Medical University
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MORI Yukio
Institute of Biological Pharmacy, Gifu Pharmaceutical University
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Tamura K
Department Of Pathology Gifu University School Of Medicine
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Yoshimi N
Department Of Pathology Faculty Of Medicine University Of The Ryukyus
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MORI Yukio
Gifu Pharmaceutical University
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Nagai Hiroichi
富山医科薬科大学和漢薬研究所
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Morishita Y
Institute Of Biological Pharmacy Gifu Pharmaceutical University
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Sugie S
Department Of Oncologic Pathology Kanazawa Medical University
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Sugie Shigeyuki
京都大学 農学研究科食品生物科学
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Sugie S
Kanazawa Medical Univ. Ishikawa
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Mori Yukio
Institute Of Biological Pharmacy Gifu Pharmaceutical University
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Morishita Y
First Department Of Pathology Gifu University School Of Medicine
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Kojima T
First Department Of Pathology Gifu University School Of Medicine
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Kinouchi T
Univ. Tokushima School Of Medicine Tokushima Jpn
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Kaneshiro Tatsuya
琉球大学 医学部病理学第1
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Toyoshi Kazumi
Department Of Pathology Gifu University School Of Medicine
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Kinjo Tatsuya
琉球大学 医学部病理学第1
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Nemoto Hideo
Laboratory Of Medical Chemistry Graduate School Of Medicine And Pharmaceutical Sciences University O
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Mori Yukio
Laboratory Of Radiochemistry Gifu Pharmaceutical University
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Kumo Toshiya
First Department Of Pathology Gifu University School Of Medicine
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Tamura Kazutoshi
Department Of Oncological Pathology Cancer Center Nara Medical University
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Nojima Hiroshi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Ohu University
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Kinouchi Takemi
Department Of Bacteriology School Of Medicine The University Of Tokushima
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Yoshimoto Masatoshi
Department Of Oncological Pathology Cancer Center Nara Medical University
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Toyoshi Kazumi
First Department Of Pathology Gifu University School Of Medicine
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Yoshimoto M
Department Of Oncological Pathology Cancer Center Nara Medical University
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Kinjo Tatsuya
Tumor Pathology University Of Ryukyus Faculty Of Medicine
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Kinjo Tatsuya
Department Of Molecular Bacteriology Graduate School Of Medicine The University Of Tokushima
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Kuwahara Tomomi
Department Of Bacteriology School Of Medicine The University Of Tokushima
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Yoshimoto Masatoshi
Surgical Center Nara Medical University Hospital
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Kinouchi Takemi
Department Of Molecular Bacteriology Graduate School Of Medicine The University Of Tokushima
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Kawamori Toshihiko
Department Of Pathology Gifu University School Of Medicine
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Toyoshi Kazumi
Gifu Collgege Of Pharmacy
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Yoshimi Naoki
School Of Pharmaceutical Sciences University Of Shizuoka
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Mizumoto Yasushi
Surgical Center Nara Medical University Hospital
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Yoshimoto Masatoshi
Gifu Pharmaceutical University
関連論文
- Lack of Enhancing Effect of Lauric Acid on the Development of Aberrant Crypt Foci in Male ICR Mice Treated with Azoxymethane and Dextran Sodium Sulfate
- Modification by curcumin of mutagenic activation of carcinogenic N-nitrosamines by extrahepatic cytochromes P-450 2B1 and 2E1 in rats
- Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1, 2-dimethylhydrazine dihydrochloride
- Tumor formation is correlated with expression of β-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice
- A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
- Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor γ ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide
- Carcinoid tumor in the female urethral orifice : Rare case report and a review of the literature
- Induction of Apoptosis by Sulindac in Azoxymethane-induced Possible Colonic Premaligmant Lesions in Rats
- Chemopreventive Effects of a Flavonoid Antioxidant Silymarin on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Urinary Bladder Carcinogenesis in Male ICR Mice
- Enhancement by Cigarette Smoke Exposure of 2-Amino-3,8-dimethylimidazo [4,5-f] quinoxaline-induced Rat Hepatocarcinogenesis in Close Association with Elevation of Hepatic CYP1A2
- Absence of mutagenic action of 5β-cholan-24-oic acid derivatives in the bacterial fluctuation and standard Ames tests.
- Common Duct Carcinoma and Obstruction in Female Hamsters Treated with N-Nitrosobis(2-oxopropyl)amine and/or Cholecystectomy.
- Suppressive Effect of Irsogladine Maleate on Diethylnitrosamine-initiated and Phenobarbital-promoted Hepatocarcinogenesis in Male F344 Rats
- Mechanistic Insights of Carcinogenesis and Anti-carcinogenesis by Dietary Compounds
- Preventive Effects of Powdered Broccoli Sprout on Azoxymethane-induced Rat Colonic Aberrant Crypt Foci
- Chemopreventive Effects of Scordinin on Diethylnitrosamine and Phenobarbital-induced Hepatocarcinogenesis in Male F344 Rats
- Dietary Prevention of Azoxymethane-Induced Colon Carcinogenesis with Rice-Germ in F344 Rats.
- β-Catenin (Ctnnb1) Gene Mutations in Diethylnitrosamine (DEN)-induced Liver Tumors in Male F344 Rats
- Modulating Effects of Diets High in ω-3 and ω-6 Fatty Acids in Initiation and Postinitiation Stages of Diethylnitrosamine-induced Hepatocarcinogenesis in Rats
- Rapid induction of replicating DNA synthesis in response to 2-amino-3, 4-dimethylimidazo[4, 5-f]quinoline in rat hepatocytes
- Regressive Effects of Various Chemopreventive Agents on Azoxymethane-induced Aberrant Crypt Foci in the Rat Colon
- Inhibitory Effects of Diallyl Disulfide or Aspirin on 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced Mammary Carcinogenesis in Rats
- Suppressive Effects of S-Methyl Methanethiosulfonate on Promotion Stage of Diethylnitrosamine-initiated and Phenobarbital-promoted Hepatocarcinogenesis Model
- Inhibitory Effect of Chlorophyllin on Diethylnitrosamine and Phenobarbital-induced Hepatocarcinogenesis in Male F344 Rats
- LACK OF INHIBITORY EFFECT OF BENZYL ISOTHIOCYANATE ON 2-AMINO-1-METHYL-6-PHENYLIMIDAZO [4,5-b]PYRIDINE (PhIP)-INDUCED MAMMARY CARCINOGENESIS IN RATS
- Suppressive Effects of Natural Antioxidants on Carcinogenesis in Digestive Organs (特別企画 〔日本環境変異原学会〕第24回大会ミニシンポジウム) -- (抗変異・抗発がんとラジカル)
- Chemopreventive Effects of Taurine on Diethylnitrosamine and Phenobarbitalinduced Hepatocarcinogenesis in Male F344 Rats
- A Xanthine Oxiedase Inhibitor 1'-Acetoxychavicol Acetate Inhibits Azoxymethane-induced Colonic Aberrant Crypt Foci in Rats.
- Chemopreventive Effect of a Xanthine Oxidase Inhibitor, l'-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis.
- Inhibitory effect of dietary monoglucosylceramide 1-O-β-glucosyl-N-2'-hydroxyarachidoyl-4,8-sphingadienine on two different categories of colon preneoplastic lesions induced by 1,2-dimethylhydrazine in F344 rats
- Genetic alterations in a patient with Turcot's syndrome
- CARCINOGENICITY EXAMINATION OF 1-NITROPYRENE OXIDES AND RELATED CHEMICALS : LACK OF THEIR TUMORIGENIC EFFECTS IN A NEWBORN MICE ASSAY
- Increased Telomerase Activities in Human Pancreatic Duct Adenocarcinomas
- Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1'-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis
- Genetic Variation in 16S-23S rDNA Internal Transcribed Spacer Regions and the Possible Use of This Genetic Variation for Molecular Diagnosis of Bacteroides Species
- Protective Effects of a Culture Supernatant of Lactobacillus acidophilus and Antioxidants on Ileal Ulcer Formation in Rats Treated with a Nonsteroidal Antiinflammatory Drug
- Culture Supernatants of Lactobacillus acidophilus and Bifidobacterium adolescentis Repress Ileal Ulcer Formation in Rats Treated with a Nonsteroidal Antiinflammatory Drug by Suppressing Unbalanced Growth of Aerobic Bacteria and Lipid Peroxidation
- Rapid Species Identification and Partial Strain Differentiation of Clostridium butyricum by PCR Using 16S-23S rDNA Intergenic Spacer Regions
- Suppression of Occurrence and Advancement of β-Catenin-accumulated Crypts, Possible Premalignant Lesions of Colon Cancer, by Selective Cyclooxygenase-2 Inhibitor, Celecoxib
- Mutagenic activation of N-nitrosobis(2-oxopropyl)amine by pancreatic juice and assessment of its ductal tumorigenicity following intraductal administration in dogs.
- Inhibitory Effects of Dietary Protocatechuic Acid and Costunolide on 7,12-Dimethylbenz[a ]anthracene-induced Hamster Cheek Pouch Carcinogenesis
- Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
- Suppression of Azoxymethane-induced Rat Colon Carcinogenesis by Dietary Administration of Naturally Occurring Xanthophylls Astaxanthin and Canthaxanthin During the Postinitiation Phase.
- Chemoprevention of Urinary Bladder Carcinogenesis by the Natural Phenolic Compound Protocatechuic Acid in Rats.
- Chemoprevention of Azoxymethane-induced Colon Carcinogenesis by Dietary Feeding of S-Methyl Methane Thiosulfonatein Male F344 Rats.
- Suppression of Azoxymethane-induced Colonic Aberrant Crypt Foci by Dietary Exposure to a Novel Synthesized Retinoidal Butenolide, 5-Hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone, in Rats.
- Modifying Effects of Naturally Occurring Products on the Development of Colonic Aberrant Crypt Foci Induced by Azoxymethane in F344 Rats.
- Enzyme cytology of alkaline phosphatase in lung cancer
- Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate
- Lack of modifying effects of 4-tert-octylphenol and benzyl butyl phthalate on 3, 2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in rats
- Chemopreventive Effect of Curcumin on N-Nitrosomethylbenzylamine-induced Esophageal Carcinogenesis in Rats
- Chemoprevention by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine(PhIP)-induced Mammary Gland Carcinogenesis in Rats
- Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis
- Promoting Effect of Sodium L-Ascorbate on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Renal Pelvic Carcinogenesis in SD/cShi Rats of Both Sexes
- N-Benzylimidazole for preparation of S9 fraction with multi-induction of metabolizing enzymes in hort-term genotoxicity assays.
- Lack of changes in the levels of liver and kidney cytochrome P-450 isozymes in p53(+/-)knockout mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
- Differences among Three Sister Strains of NON/Shi Mice in Sensitivity to Urinary Tract Carcinogenesis by N-Butyl-N-(4-hydroxybutyl)nitrosamine.
- Effect of Cigarette Smoke on the Mutagenic Activation of Environmental Carcinogens by Rodent Liver.
- High Susceptibility of p53(+/-)Knockout Mice in N-Butyl-N-(4-hydroxybutyl)nitrosamine Urinary Bladder Carcinogenesis and Lack of Frequent Mutation in Residual Allele.
- Telomerase Activity Correlates with Growth of Transplantable Osteosarcomas in Rats Treated with cis-Diammine Dichloroplatinum or the Angiogenesis Inhibitor AGM-1470
- Comutagenic Effect of Bile Acids with 2-Aminoanthracene, 1,2-Dimethylhydrazine and Pancreas-carcinogenic N-Nitroso Compounds.
- Enhancement of N-nitrosodiethylamine-Initiated Hepatocarcinogenesis Caused by a Colchicine-induced Cell Cycle Disturbance in Partially Hepatectomized Rats.
- Lack of significant tumor induction by endogeneously formed N-nitrosobis(2-hydroxypropyl)amine in rats fed tris(2-hydroxypropyl)-amine and sodium nitrite.
- Effect of cigarette smoke on the mutagenic activation of various carcinogens in hamster.
- A New cytochrome P450 inducer for Ames test.
- Expression of heterodimeric (placental-intestinal) hybrid alkaline phosphatase in KB cells.
- Chemoprevention of Carcinogenesis by Organoselenium Compounds
- Antimutagenicity of Murdannia Loriformis in the Salmonella mutation assay and its inhibitory effects on azoxmethaneinduced DNA methylation and aberrant crypt focus formation in male F344 rats
- Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethaneinduced DNA methylation and aberrant crypt focus formation in male F344 rats
- SUPPRESSIVE EFFECTS OF CHLOROGENIC ACID ON N-METHYL-N-NITROSOUREA-INDUCED GLANDULAR STOMACH CARCINOGENESIS IN MALE F344 RATS
- Inhibitory Effects of Nabumetone, a Cyclooxygenase-2 Inhibitor, and Esculetin, a Lipoxygenase Inhibitor, on N-Methyl-N-nitrosourea-induced Mammary Carcinogenesis in Rats
- Inhibitory Effect of NS-398, a Selective Cyclooxygenase-2 Inhibitor, on Azoxymethane-induced Aberrant Crypt Foci in Colon Carcinogenesis of F344 Rats
- Inhibition by Green Tea Extract of Diethylnitrosamine-initiated but Not Choline-deficient, L-Amino Acid-defined Diet-associated Development of Putative Preneo-plastic, Glutathione S-Transferase Placental Form-positive Lesions in Rat Liver
- Genotoxicity of a Variety of Azobenzene and Aminoazobenzene Compounds in the Hepatocyte/DNA Repair Test and the Salmonella/Mutagenicity Test.
- Activation of Carcinogenic N-Nitrosopropylamines to Mutagens by Lung and Pancreas S9 Fractions from Various Animal Species and Man.
- A Comparative Study of the Mutagenic Activation of N-Nitrosopropylamines by Various Animal Species and Man : Evidence for a Cytochrome P-450 Dependent Reaction.
- Mutagenic Activation of Carcinogenic N-Nitrosopropylamines by Liver S9 Fractions from Mice, Rats, and Hamsters : Evidence for a Cytochrome P-450 Dependent Reaction.
- Role of Alkaline Phosphatase in Phosphate Uptake into Brush Border Membrane Vesicles from Human Intestinal Mucosa.
- In Vitro Synthesis of Superoxide Dismutases of Rat Liver.
- HUMAN AND RAT LIVER-CYTOSOLIC COMPONENTS INVOLVED IN MUTAGENIC ACTIVATION OF AMINO ACID PYROLYSATES
- CYTOSOLIC COMPONENTS INVOLVED IN MUTAGENIC ACTIVATION OF CARCINOGENIC AMINOAZO COMPOUNDS
- Studies on the Disposition of Suprofen Ointment After Occlusive Topical Application (II) : Metabolism, Absorption to Inflammed Site after Single Application, and Absorption, Distribution and Excretion after Consecutive Applicati
- Studies on the Disposition of Suprofen Ointment After Occlusive Topical Application (I) : Absorption, Distribution and Excretion in Rats and Absorption and Excretion in Guinea Pigs.
- Species Differences in the Metabolism of Suprofen in Laboratory Animals and Man.
- INHIBITION OF HUMAN DIPEPTIDASES BY β-LACTAM ANTIBIOTICS
- Chemopreventive Effects of Plant Derived Phenolic, Organosulfur and Other Compounds on Carcinogenesis in Digestive Organs
- Overexpression of Midkine in Pancreatic Duct Adenocarcinomas Induced by N-Nitrosobis(2-oxopropyl)amine in Hamsters and Their Cell Lines
- Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine(BHP) in rats administered bis(2-hydroxypropyl)-amine(BHPA) and sodium nitrite(SN).
- Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.
- Carcinogenic Potency of N-nitrosomethyl(2-hydroxypropyl)amine and Other Metabolic Relatives of N-Nitrosobis(2-hydroxypropyl)amine by Single Intraperitoneal Injection on the Lung of Rats.
- Mutagenesis of Isopropanolamines and Ethanolamines after Reaction with Sodium Nitrite.
- METABOLIC ACTIVATION OF N-NITROSOBIS (2-HYDROXYPROPYL) AMINE BY RATS
- Genotoxicity of Carcinogenic N-Nitrosopropylamine Derivatives in the Hepatocyte Primary Culture/DNA-Repair Test.
- Inhibitory Effect of Organic Solvents on the Mutagenicity of N-Nitrosodialkylamines in Salmonella.
- Mutagenic Activation of Carciuogenic N-Nitrosopropylamines by Rat Liver : Evidence for a Cytochrome P-450 Dependent Reaction.
- AN ENZYMIC MECHANISM FOR MUTAGENIC ACTIVATION OF CARCINOGENIC AMINOAZO DYES
- Hepatocarcinogenic Activities of Hydorxymethyl Derivatives of 4-(N, N-Dimethylamino)azobenzene in ACI/N Rats.
- Mutagenicity of N-Nitrosodiethanolamine in the Salmonella/Microsome Test.
- MEASUREMENT OF UNSCHEDULED DNA SYNTHESIS ON ALKYLATING CARCINOGENS IN RAT INTESTINAL MUCOSAL CELLS FROM DIFFERENT SITES
- Differences Among Three Sister Strains of NON/Shi Mice in Sensitivity to Urinary Tract Carcinogenesis by N-Butyl-N-(4-hydroxybutyl)nitrosamine