Induction of Apoptosis by Sulindac in Azoxymethane-induced Possible Colonic Premaligmant Lesions in Rats
スポンサーリンク
概要
- 論文の詳細を見る
- 2002-03-31
著者
-
SUGIE Shigeyuki
Department of Oncologic Pathology, Kanazawa Medical University
-
Mori H
Division Of Pathology National Institute Of Health Sciences
-
Tamura K
Department Of Pathology Gifu University School Of Medicine
-
HIROSE Yoshinobu
Department of Pathology, Gifu University School of Medicine
-
MORI Hideki
First Department of Pathology, Gifu University School of Medicine
-
KUMO Toshiya
First Department of Pathology, Gifu University School of Medicine
-
YAMADA Yasuhiro
First Department of Pathology, Gifu University School of Medicine
-
HIROSE Yoshinobu
First Department of Pathology, Gifu University School of Medicine
-
KATAYAMA Masaki
First Department of Pathology, Gifu University School of Medicine
-
SAKATA Keiko
First Department of Pathology, Gifu University School of Medicine
-
HARA Akira
First Department of Pathology, Gifu University School of Medicine
-
SAJI Shigetoyo
Second Department of Sugery, Gifu University School of Medicine
-
Sugie S
Department Of Oncologic Pathology Kanazawa Medical University
-
Sugie Shigeyuki
京都大学 農学研究科食品生物科学
-
Sugie S
Kanazawa Medical Univ. Ishikawa
-
Yamada Y
Department Of Oncologic Pathology Kanazawa Medical University
-
Hirose Y
Department Of Pathology Gifu University School Of Medicine
-
Yonei Hiroshi
Research And Development Division Wakayama Agricultural Processing Research Corporation
-
Kakumoto Mikio
岐阜大学 病理
-
Kakumoto Mikio
Department Of Biochemistry Gifu Pharmaceutical University
-
Kakumoto Mikio
Biochemistry Laboratory Gifu Pharmaceutical University
-
Satoh Kumiko
Department Of Pathology Gifu University School Of Medicine
-
Makita Hiroki
岐阜大学 第1病理
-
Hara A
Laboratory Of Biochemistry Gifu Pharmaceutical University
-
Hara Akira
First Department Of Internal Medicine. Fukui Medical School
-
Kojima T
First Department Of Pathology Gifu University School Of Medicine
-
Toyoshi Kazumi
Department Of Pathology Gifu University School Of Medicine
-
Kinjo Tatsuya
琉球大学 医学部病理学第1
-
Kawamori T
National Cancer Center Res. Inst. Tokyo
-
Katayama Masaki
Department Of Pathology Gifu University School Of Medicine
-
Satoh K
Department Of Pathology Gifu University School Of Medicine
-
Hirose Yoshinobu
Department Of Pathology Gifu University School Of Medicine
-
Hara A
Department Of Applied Biological Chemistry Faculty Of Agriculture Meijo University
-
Hara Akira
Shonan Institute Of Technology
-
Hirota M
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
-
Hara Akira
Lab. Of Biochemistry Gifu Pharmaceutical Univ.
-
Kumo Toshiya
First Department Of Pathology Gifu University School Of Medicine
-
Yasui Yumiko
Department Of Oncologic Pathology Kanazawa Medical University
-
Kuwahara Tomomi
Department Of Molecular Bacteriology Graduate School Of Medicine The University Of Tokushima
-
Hara Akira
Laboratory Of Biochemistry Gifu Pharmaceutical University
-
Hara Akira
From The Third Division Department Of Internal Medicine Kyoto University
-
Toyoshi Kazumi
First Department Of Pathology Gifu University School Of Medicine
-
Yamada Y
Department Of Physics Faculty Of Science Kyoto University
-
Mori Hideki
First Department Of Pathology Gifu University School Of Medicine
-
Kakumoto Mikio
Department Of Pathology Gifu University School Of Medicine
-
Kinjo Tatsuya
Tumor Pathology University Of Ryukyus Faculty Of Medicine
-
Kawanaka M
Department Of Pathology Gifu University School Of Medicine
-
Kinjo Tatsuya
Department Of Molecular Bacteriology Graduate School Of Medicine The University Of Tokushima
-
Kinouchi Takemi
Department Of Molecular Bacteriology Graduate School Of Medicine The University Of Tokushima
-
Kawamori Toshihiko
Department Of Pathology Gifu University School Of Medicine
-
Toyoshi Kazumi
Gifu Collgege Of Pharmacy
-
Hara Akira
First Department of Internal Medicine, Fukui-Medical School
関連論文
- A 55-week chronic toxicity study of dietary administered kojic acid (KA) in male F344 rats
- Lack of Enhancing Effect of Lauric Acid on the Development of Aberrant Crypt Foci in Male ICR Mice Treated with Azoxymethane and Dextran Sodium Sulfate
- Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide
- Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats
- Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation
- Inhibitory Effects of Octreotide Acetate, a Somatostatin Analog, on Spontaneous Chronic Pancreatitis in WBN/Kob Rats
- Rapid Screening for Chemopreventive Agents in Herbal Extracts in a PhIP Rat Model with DNA Adduct and Cell Proliferation as End-Points
- DNA Adduct Formation, Nucleolar Segregation and Cell Proliferation in Rats Treated with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats
- Lack of enhancement of susceptibility to mammary and thyroid carcinogenesis in rats exposed to DMBA and DHPN following prepubertal iodine deficiency
- Modification by curcumin of mutagenic activation of carcinogenic N-nitrosamines by extrahepatic cytochromes P-450 2B1 and 2E1 in rats
- In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Comparison of enhancing effects of different goitrogen treatments in combination with β-estradiol-3-benzoate for establishing a rat two-stage thyroid carcinogenesis model to detect modifying effects of estrogenic compounds
- In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Catechol enhanced mice hepatotoxicity treated with acetaminophen(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Lack of Modifying Effects of Combined Treatment of t-butylhydroquinone and Sodium Nitrite on Forestomach Carcinogenesis in rasH2 Mice Initiated with N-ethyl-N-nitrosourea
- Lack of Initiating Activity of Kojic Acid on Hepatocarcinogenesis in F344 Rats
- Electron Microscopical Evidence of the Protective Function of Thioredoxin (TRX/ADF) Transgene against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced Cellular Toxicity in the Liver and Brain
- Tumorigenic Susceptibility of Catechol on the Gastric Mucosa in rasH2 Mice
- P8-27 Susceptibility to pentachlorophenol, a mouse liver carcinogen in Nrf2-deficient mice(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Lack of Modifying Effect of Glycerol in Pulmonary Carcinogenesis in rasH2 Mice Induced by Urethane or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
- P7-44 Toxicity Evaluation of Bt protein with 28-days dietary administration to gastric-acid reduced rat models(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- P6-43 Screening of chemopreventive agents using a medium-term pancreas carcinogenesis model in hamsters(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1, 2-dimethylhydrazine dihydrochloride
- Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate
- Tumor formation is correlated with expression of β-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice
- A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
- Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl) nitrosamine in rats after initiation
- Modulatory effects of hepatic, renal or thyroidal impairments on amitrole-induced thyroid carcinogenesis in rats pretreated with DHPN (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A possible role of oxidative stress in potassium bromate (KBrO_3) carcinogenesis (ACTIVE OXYGEN) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Safety evaluetion of Bt protein by dietary administration to a gastro-intestinal impairment rat model (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Promoting Effects of Ethinylestradiol but not Atrazine on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in ICR Mice
- Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor γ ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide
- Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl) nitrosamine
- Modifying Effects of 2,6-Dimethylaniline on Nasal Carcinogenesis in RasH2 Mice Initiated with 4-Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Lack of Modifying Effects of 2,6-Dimethylaniline on Lung Carcinogenesis in Transgenic Mice Carrying Human Prototype c-Ha-ras Gene Initiated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Carcinoid tumor in the female urethral orifice : Rare case report and a review of the literature
- Difference in the Types of Uterine Tumors between Heterozygous p53-deficient and Wild Type CBA Mice Treated with Ethinylestradiol after N-ethyl-N-nitrosourea Initiation
- Modifying effect of atrazine on DMBA-induced mammary carcinogenesis in ovariectomized rats.(GENERAL SESSION BY POSTER PRESENTATION)(CARCINOGENICITY)
- Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis : Results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A Repeated 28 Days Oral Dose Toxicity Study of Genistein in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.(GENERAL SESSION BY POSTER PRESENTATION)(ENDOCRINE SYSTEM)
- Modifying Effects of Genistein, 4-Nonylphenol and Methoxychlor on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in RasH2 Transgenic Mice Harboring a Human Prototype C-Ha-ras Gene
- The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens
- Enhancing Effects β-Estradiol 3-Benzoate but Not Methoxychlor on the Promotion/Progression Stage of Chemically-induced Mammary Carcinogenesis in Ovariectomized Rats
- GONADAL TOXICITY OF AN ETHANOL EXTRACT OF PSORALEA CORYLIFOLIA IN A RAT 90-DAY REPEATED DOSE STUDY
- Induction of Apoptosis by Sulindac in Azoxymethane-induced Possible Colonic Premaligmant Lesions in Rats
- The Utility of N-nitrosamines as Initiators for a 26-Week Rat Two-Stage Nasal Carcinogenesis Model
- Chemopreventive Effects of a Flavonoid Antioxidant Silymarin on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Urinary Bladder Carcinogenesis in Male ICR Mice
- Enhancement by Cigarette Smoke Exposure of 2-Amino-3,8-dimethylimidazo [4,5-f] quinoxaline-induced Rat Hepatocarcinogenesis in Close Association with Elevation of Hepatic CYP1A2
- P10-09 A Repeated 28 Days Oral Dose Toxicity Study of Methoxychlor in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A Repeated 28 Days Oral Dose Toxicity Study of Genistein in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.(GENERAL SESSION BY POSTER PRESENTATION)(ENDOCRINE SYSTEM)
- P10-09 A Repeated 28 Days Oral Dose Toxicity Study of Methoxychlor in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.
- Suppressive Effect of Irsogladine Maleate on Diethylnitrosamine-initiated and Phenobarbital-promoted Hepatocarcinogenesis in Male F344 Rats
- Mechanistic Insights of Carcinogenesis and Anti-carcinogenesis by Dietary Compounds
- Preventive Effects of Powdered Broccoli Sprout on Azoxymethane-induced Rat Colonic Aberrant Crypt Foci
- Chemopreventive Effects of Scordinin on Diethylnitrosamine and Phenobarbital-induced Hepatocarcinogenesis in Male F344 Rats
- Dietary Prevention of Azoxymethane-Induced Colon Carcinogenesis with Rice-Germ in F344 Rats.
- β-Catenin (Ctnnb1) Gene Mutations in Diethylnitrosamine (DEN)-induced Liver Tumors in Male F344 Rats
- Modulating Effects of Diets High in ω-3 and ω-6 Fatty Acids in Initiation and Postinitiation Stages of Diethylnitrosamine-induced Hepatocarcinogenesis in Rats
- Rapid induction of replicating DNA synthesis in response to 2-amino-3, 4-dimethylimidazo[4, 5-f]quinoline in rat hepatocytes
- Regressive Effects of Various Chemopreventive Agents on Azoxymethane-induced Aberrant Crypt Foci in the Rat Colon
- Inhibitory Effects of Diallyl Disulfide or Aspirin on 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced Mammary Carcinogenesis in Rats
- Suppressive Effects of S-Methyl Methanethiosulfonate on Promotion Stage of Diethylnitrosamine-initiated and Phenobarbital-promoted Hepatocarcinogenesis Model
- Inhibitory Effect of Chlorophyllin on Diethylnitrosamine and Phenobarbital-induced Hepatocarcinogenesis in Male F344 Rats
- LACK OF INHIBITORY EFFECT OF BENZYL ISOTHIOCYANATE ON 2-AMINO-1-METHYL-6-PHENYLIMIDAZO [4,5-b]PYRIDINE (PhIP)-INDUCED MAMMARY CARCINOGENESIS IN RATS
- Suppressive Effects of Natural Antioxidants on Carcinogenesis in Digestive Organs (特別企画 〔日本環境変異原学会〕第24回大会ミニシンポジウム) -- (抗変異・抗発がんとラジカル)
- Chemopreventive Effects of Taurine on Diethylnitrosamine and Phenobarbitalinduced Hepatocarcinogenesis in Male F344 Rats
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model : Biological impact of capsular inflammation and reduced cyclooxygenase-2 expression
- Suppression of N-Nitrosomethylbenzylamine-induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1'-Acetoxychavicol Acetate.
- CARCINOGENICITY EXAMINATION OF 1-NITROPYRENE OXIDES AND RELATED CHEMICALS : LACK OF THEIR TUMORIGENIC EFFECTS IN A NEWBORN MICE ASSAY
- Suppression of Occurrence and Advancement of β-Catenin-accumulated Crypts, Possible Premalignant Lesions of Colon Cancer, by Selective Cyclooxygenase-2 Inhibitor, Celecoxib
- Enzyme cytology of alkaline phosphatase in lung cancer
- Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate
- Lack of modifying effects of 4-tert-octylphenol and benzyl butyl phthalate on 3, 2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in rats
- Chemopreventive Effect of Curcumin on N-Nitrosomethylbenzylamine-induced Esophageal Carcinogenesis in Rats
- Chemoprevention by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine(PhIP)-induced Mammary Gland Carcinogenesis in Rats
- Chemoprevention of Carcinogenesis by Organoselenium Compounds
- Modifying Effects of Ferulic Acid on Azoxymethane-Induced Colon Carcinogenesis in F344 Rats.
- Involvement of Lipid Peroxidation in Spontaneous Pancreatitis in WBN/Kob Rats
- Genotoxicity of a Variety of Azobenzene and Aminoazobenzene Compounds in the Hepatocyte/DNA Repair Test and the Salmonella/Mutagenicity Test.
- Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model
- Pathological assessment of the nervous and male reproductive systems of rat offspring exposed maternally to acrylamide during the gestation and lactation periods-a preliminary study
- Chemopreventive Effects of Plant Derived Phenolic, Organosulfur and Other Compounds on Carcinogenesis in Digestive Organs
- Genotoxicity of Carcinogenic N-Nitrosopropylamine Derivatives in the Hepatocyte Primary Culture/DNA-Repair Test.
- Hepatocarcinogenic Activities of Hydorxymethyl Derivatives of 4-(N, N-Dimethylamino)azobenzene in ACI/N Rats.
- MEASUREMENT OF UNSCHEDULED DNA SYNTHESIS ON ALKYLATING CARCINOGENS IN RAT INTESTINAL MUCOSAL CELLS FROM DIFFERENT SITES
- Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation
- Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity
- Carcinogenic potential of alizarin and rubiadin, components of madder color, in a rat medium-term multi-organ bioassay