In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 2005-10-31
著者
-
Umemura T
Division Of Pathology National Institute Of Health Sciences
-
Hirose Masao
Division of Pathology, National Institute of Health Sciences
-
Nishikawa Akiyoshi
Division of Pathology, National Institute of Health Sciences
-
Mori H
Division Of Pathology National Institute Of Health Sciences
-
Mitsumori Kunitoshi
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
-
Mitsumori Kunitoshi
東京大学医科学研究所 癌細胞シグナル分野
-
Mitsumori Kunitoshi
国立医薬品食品衛生研究所 病理部
-
KUROIWA Yuichi
Division of Pathology, National Institute of Health Sciences
-
ISHII Yuji
Division of Pathology, National Institute of Health Sciences
-
UMEMURA Takashi
Division of Pathology, National Institute of Health Sciences
-
KANKI Keita
Division of Pathology, National Institute of Health Sciences
-
NOHMI Takehiko
Division of Genetics and Mutagenesis, National Institute of Health Sciences
-
MASUMURA Ken-ichi
Division of Genetics & Mutagenesis, National Institute of Health Sciences
-
KODAMA Yukio
Division of Toxicology, National Institute of Health Sciences
-
Nishimura T
Division Of Environmental Chemistry
-
Mitsumori K
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
-
Yasuhara Kazuo
Divisions Of Toxicology National Institute Of Hygienic Sciences
-
Yasuhara Kazuo
Division Of Pathology National Institute Of Health Sciences
-
Hirose Masao
国立医薬品食品衛生研究所 病理
-
Hirose M
Division Of Pathology National Institute Of Health Sciences:food Safety Commission
-
Kanki K
Division Of Pathology National Institute Of Health Sciences
-
Kanki Keita
国立医薬品食品衛生研究所 病理部
-
Kanki Keita
Division Of Pathology National Institute Of Health Sciences
-
KAWASAKI Yasushi
Div of Cellular and Molecular Toxicology
-
Hoshi Manabu
大阪市立大学 医学部病理学
-
Kodama Yukio
Division Of Pathology National Institute Of Health Sciences
-
Kitamura Y
Division Of Pathology National Institute Of Health Sciences
-
Makita Hiroki
岐阜大学 第1病理
-
Ishii Yuji
Division Of Pathology National Institute Of Health Sciences
-
安原 加壽雄
San-ei Gen F.f.i. Inc.
-
Kurokawa Y
Division Of Toxicology National Institute Of Health Sciences
-
Mitsumori Kunitoshi
Department Of Pathology National Institute Of Health Sciences
-
Hirose Masao
Division Of Pathology National Institute Of Health Sciences
-
Nishikawa A
Div. Of Pathology National Inst. Of Health Sciences
-
Nishikawa Akiyoshi
Division Of Pathology Biology Safety Research Center National Institute Of Health Sciences
-
Nishikawa A
National Inst. Health Sci. Tokyo Jpn
-
Hosono M
Aburahi Laboratories Shionogi Research Laboratories Shionogi Co Ltd.
-
Nishikawa A
National Institute Of Health Science Osaka Branch National Institute Of Health Sciences
-
Umemura Takashi
Division Of Pathology National Institute Of Health Sciences
-
Kamimura Yasuhiro
Safety Evaluation Lab. Yoshitomi Pharm.
-
Yoshikawa Katsunori
Department Of Bioinformatic Engineering Graduate School Of Information Science And Technology Osaka
-
Kodama Yukio
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
Hirose Masao
Department Of Pathology Nagoya Higashi Municipal Hospital
-
Unno Takashi
Division Of Pathology National Institute Of Health Sciences
-
Umemura T
Hokkaido Univ. Sapporo Jpn
-
Umemura Takashi
Division Of Pathology National Institute Of Health Science
-
Matsumoto K
Drug Safety Research Laboratories Pharmaceutical Research Division Takeda Chemical Industries Ltd.:l
-
Kurokawa Y
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
Kodama Y
Biological Safety Research Center National Institute Of Health Science
-
三森 国敏
Division Of Pathology National Institute Of Health Sciences
-
Unno Takashi
Japan Pharmaceutical Manufactures Association (jpma):kanebo Ltd
-
Kuroiwa Yuichi
Division Of Pathology National Institute Of Health Sciences
-
Nohmi Takehiko
Division Of Genetics And Mutagenesis National Institute Of Health Sciences
-
Kawasaki Yasushi
National Institute Of Health Sciences
-
Kashida Y
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
-
Kurokawa Yuji
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Kawasaki Yasushi
Div.of Toxicol. National Institute Of Health Sciences
-
Kodama Yukio
Cel. Mol. Tox. Div. Nihs
-
Matsumoto K
Laboratory Of Veterinary Pathology Tokyo University Of Agriculture And Technology
-
Kuroiwa Yuichi
Division Of Cellular And Molecular Toxicology Kangwon National University
-
Mori Hideki
First Department Of Pathology Gifu University School Of Medicine
-
Kanki Keita
Division Of Molecular And Genetic Medicine Tottori University
-
Umemura Takashi
Laboratory Of Comparative Pathology Graduate School Of Veterinary Medicine Hokkaido University
-
Kanki Keita
Division Of Molecular And Genetic Medicine Department Of Genetic Medicine And Regenerative Therapeut
-
Katakura Yoshio
Department Of Life Science And Bioengineering Faculty Of Chemistry Materials And Bioengineering Kans
-
Yasuhara Kazuo
Division Of Toxicology Biological Safety Research Center National Institute Of Hygienic Sciences
-
Katakura Yoshio
Department Of Biotechnology Faculty Of Engineering Osaka University
-
Ishii Yuji
Division Of Pathology National Institute Of Health Science
関連論文
- A 55-week chronic toxicity study of dietary administered kojic acid (KA) in male F344 rats
- Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats
- Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation
- Inhibitory Effects of Octreotide Acetate, a Somatostatin Analog, on Spontaneous Chronic Pancreatitis in WBN/Kob Rats
- Rapid Screening for Chemopreventive Agents in Herbal Extracts in a PhIP Rat Model with DNA Adduct and Cell Proliferation as End-Points
- DNA Adduct Formation, Nucleolar Segregation and Cell Proliferation in Rats Treated with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats
- Lack of enhancement of susceptibility to mammary and thyroid carcinogenesis in rats exposed to DMBA and DHPN following prepubertal iodine deficiency
- In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Comparison of enhancing effects of different goitrogen treatments in combination with β-estradiol-3-benzoate for establishing a rat two-stage thyroid carcinogenesis model to detect modifying effects of estrogenic compounds
- In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Catechol enhanced mice hepatotoxicity treated with acetaminophen(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Lack of Modifying Effects of Combined Treatment of t-butylhydroquinone and Sodium Nitrite on Forestomach Carcinogenesis in rasH2 Mice Initiated with N-ethyl-N-nitrosourea
- Lack of Initiating Activity of Kojic Acid on Hepatocarcinogenesis in F344 Rats
- Tumorigenic Susceptibility of Catechol on the Gastric Mucosa in rasH2 Mice
- P8-27 Susceptibility to pentachlorophenol, a mouse liver carcinogen in Nrf2-deficient mice(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Lack of Modifying Effect of Glycerol in Pulmonary Carcinogenesis in rasH2 Mice Induced by Urethane or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
- LACK OF MODIFYING EFFECTS OF EUGENOL ON DEVELOPMENT OF LUNG PROLIFERATIVE LESIONS INDUCED BY URETHANE IN TRANS-GENIC MICE CARRYING THE HUMAN PROTOTYPE c-Ha-ras GENE
- Lack of Modifying Effects of Cinnamaldehyde on Development of Lung Proliferative Lesions Induced by Urethane in Transgenic Mice Carrying the Human Prototype c-Ha-ras Gene
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
- P7-44 Toxicity Evaluation of Bt protein with 28-days dietary administration to gastric-acid reduced rat models(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- P6-43 Screening of chemopreventive agents using a medium-term pancreas carcinogenesis model in hamsters(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate
- Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl) nitrosamine in rats after initiation
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A possible role of oxidative stress in potassium bromate (KBrO_3) carcinogenesis (ACTIVE OXYGEN) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Safety evaluetion of Bt protein by dietary administration to a gastro-intestinal impairment rat model (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Promoting Effects of Ethinylestradiol but not Atrazine on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in ICR Mice
- Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl) nitrosamine
- Modifying Effects of 2,6-Dimethylaniline on Nasal Carcinogenesis in RasH2 Mice Initiated with 4-Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Lack of Modifying Effects of 2,6-Dimethylaniline on Lung Carcinogenesis in Transgenic Mice Carrying Human Prototype c-Ha-ras Gene Initiated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Difference in the Types of Uterine Tumors between Heterozygous p53-deficient and Wild Type CBA Mice Treated with Ethinylestradiol after N-ethyl-N-nitrosourea Initiation
- Modifying effect of atrazine on DMBA-induced mammary carcinogenesis in ovariectomized rats.(GENERAL SESSION BY POSTER PRESENTATION)(CARCINOGENICITY)
- Effects of Antioxidant 1-O-Hexy1-2,3,5-trimethylhydroquinone or Ascorbic Acid on Carcinogenesis Induced by Administration of Aminopyrine and Sodium Nitrite in a Rat Multi-organ Carcinogenesis Model
- Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis : Results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A Preliminary Study of the Effect of Plantago Ovata Forsk on the Development of 7, 12-Dimethylbenz[a]anthracene-initiated Rat Mammary Tumors under the Influence of Hypercholesterolemia
- In vivo Approaches to Study Mechanism of Action of Genotoxic Carcinogens
- Mechanistic study on hepatocarcinogenesis induced by dicyclanil in mice : possible involvement of oxidative stress(Proceedings of the 32nd Annual Meeting)
- Establishment of an in vivo Highly Metastatic Rat Hepatocellular Carcinoma Model
- Combined Chemopreventive Effects of Perilla or Corn Oil and Indomethacin in a Rat Medium-Term Multiorgan Carcinogenesis Model
- Modifying Effects of Genistein, 4-Nonylphenol and Methoxychlor on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in RasH2 Transgenic Mice Harboring a Human Prototype C-Ha-ras Gene
- The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens
- Enhancing Effects β-Estradiol 3-Benzoate but Not Methoxychlor on the Promotion/Progression Stage of Chemically-induced Mammary Carcinogenesis in Ovariectomized Rats
- GONADAL TOXICITY OF AN ETHANOL EXTRACT OF PSORALEA CORYLIFOLIA IN A RAT 90-DAY REPEATED DOSE STUDY
- The Utility of N-nitrosamines as Initiators for a 26-Week Rat Two-Stage Nasal Carcinogenesis Model
- Enhancement by Cigarette Smoke Exposure of 2-Amino-3,8-dimethylimidazo [4,5-f] quinoxaline-induced Rat Hepatocarcinogenesis in Close Association with Elevation of Hepatic CYP1A2
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- Prevention by 2-Mercaptoethane Sulfonate and N-Acetylcysteine of Renal Oxidative Damage in Rats Treated with Ferric Nitrilotriacetate
- 3A-08 A Chronic Inhalation Study of p-Dichlorobenzene in the F344 Rat
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model : Biological impact of capsular inflammation and reduced cyclooxygenase-2 expression
- A SURVEY OF THE VALUES OF CLINICAL CHEMISTRY PARAMETERS OBTAINED FOR A COMMON RAT BLOOD SAMPLE IN NINETY-EIGHT JAPANESE LABORATORIES
- Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
- Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice
- Involvement of Lipid Peroxidation in Spontaneous Pancreatitis in WBN/Kob Rats
- Possible enhancing effects of atrazine on growth of 7, 12-dimethylbenz(a) anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats
- Renal Carcinogenicity of Concurrently Administered Fish Meal and Sodium Nitrite in F344 Rats
- "P-22 A Combination Toxicity Study of Sodium Ascorbate and Sodium Nitrite In Rats
- TOXICITY STUDY OF A RUBBER ANTIOXIDANT, 2-MERCAPTOBENZIMIDAZOLE, BY REPEATED ORAL ADMINISTRATION TO RATS
- A 13-WEEK TOXICITY STUDY OF SIMULTANEOUS ADMINISTRATION OF COCHINEAL AND ALUMINUM POTASSIUM SULFATE IN RATS
- Impaired Myelinogenesis and Early Maturation of Oligodendrocytes in Black Tremor Hamster with Central Nervous System Myelin Deficiency
- Sustained hypomyelination and high serum thyroid hormone in aged black tremor hamster
- "P-12 The effects of 90-day feeding of Aramite or other herbicides of diphenyl ether group on livers, gall-bladders and bile ducts in dogs.
- Sample surveillance for clinical pathology testing.
- B-22 A 28-DAY REPEATED DOSE TOXICITY TEST AND THE TIME COURSE OF CHOLINESTERASE ACTIVITY TEST FOR CHLORPYRIFOS IN WISTAR RAT
- B38 COMPARISON OF TOXICITY OF p-DCB IN MALE AND FEMALE RATS
- "P-35 Contribution of Oxidative Stress to Rat Hepatotoxicity induced by 2-Nitropropane : Lipid Peroxidation and Inhibitory Effect of Green Tea.
- COMRARISON OF TOXICITY OF p-DICHLOROBENZENE (p-DCB) GIVEN ORALLY AND BY INHALATION
- O-55 HEMATOTOXICICOLOGIC CHARACTERISTICS FOR OXIDATIVE STRESSES INTRANSGENIC AND/OR KNOCK-OUT MICE FOR THIOREDOXIN/ADF GENE.(Proceedings of the 27th Annual Meeting)
- 21B-10-4 Benzene hemopoietic toxicity revisited- a new concept.
- 3A-09 Hemopoietic Stem-Cell Kinetics Evaluated by Bromodeoxyuridine Incorporation Followed by Near-UV Exposure to Kill Cycling Stem Cells (BUUV). 2) Bone Marrow Cells from Mice Carrying Human c-myc Proto-Oncogene with Promoters Combined with Immunoglobuli
- "P-8 Experimental myelodysplasia induced by Azidothymidine (AZT) : Hemopoietic Stem Cell Kinetics And Pathological Findings.
- Sample surveillance for clinical pathology testing(2) Analysis of blood chemical data
- 28-DAY REPEATED-DOSE ORAL TOXICITY STUDY OF 2-MERCAPTOBENZIMIDAZOLE, A RUBBER ANTIOXIDANT, IN RATS
- A 14-WEEK ORAL TOXICITY STUDY OF TRIBUTOXYETHYL PHOSPHATE(TBEP) IN RATS
- Uterine Carcinosarcoma in a 2-year-old Female Wistar Hannover GALAS Rat
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Chronic cadmium treatment induces islet B cell injury in ovariectomized cynomolgus monkeys
- P10-16 Increased osteoid volume and iron deposition of the Iumbar vertebra in a chronic cadmium toxicosis model of cynomolgus monkeys.
- 21D-04-1 Quantitative Analysis of Bone Lesion in Ovariectomized Cynomolgus Monkeys Given Repeated Intravenous Injections of CdCl_2.
- Comparison of Antibody Titers in Rabbits Following Immunization with Inactivated Influenza Virus via Subarachnoidal or Subcutaneous Route
- Efficacy of Intracerebral Immunization against Pseudorabies Virus in Mice
- In vitro demonstration of neural transmission of avian influenza A virus
- Laboratory of Comparative Pathology
- The Effects of a Vitamin D-deficient Diet on Chronic Cadmium Exposure in Rats
- ACUTE TOXICITY OF CADMIUM IN RATS WITH OR WITHOUT CADMIUM PRETREATMENT
- 302 EFFECTS OF CADMIUM CHLORIDB ON THE BLOOD AND URINARY EXAMINATIONS IN OVARIECTOMIZED RATS
- Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency
- In vivo genotoxicity of 1-methylnaphthalene from comprehensive toxicity studies with B6C3F1 gpt delta mice
- Uterine Carcinosarcoma in a 2-year-old Female Wistar Hannover GALAS Rat
- Reporter gene mutation in the livers of gpt delta mice treated with 5-(hydroxymethyl)-2-furfural, a contaminant of various foods