"P-35 Contribution of Oxidative Stress to Rat Hepatotoxicity induced by 2-Nitropropane : Lipid Peroxidation and Inhibitory Effect of Green Tea.
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1996-12-20
著者
-
Umemura T
Division Of Pathology National Institute Of Health Sciences
-
UMEMURA Takashi
Division of Pathology, National Institute of Health Sciences
-
Kitajima Satoshi
Department Of Environmental Health And Toxicology Tokyo Metropolitan Institute Of Public Health
-
Satoh Kanako
東京都健康安全研究センター 環境保健部
-
HASEGAWA Ryuichi
Division of Medical Safety Science, National Institute of Health Sciences
-
Sai Kimie
Divislon Of Toxicology National Institute Of Health Sciences
-
Sai Kimie
Division Of Biosignaling National Institute Of Health Sciences
-
Sai-kato Kimie
Division Of Toxicology
-
KAWASAKI Yasushi
Div of Cellular and Molecular Toxicology
-
Hasegawa Ryuichi
National Institute Of Health Sciences
-
Hasegawa Ryuichi
Division Of Toxicology National Institute Of Health Sciences
-
INOUE Tohru
Division of Toxicology
-
KUROKAWA Yuji
Division of Toxicology
-
Sekita Kiyoshi
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
INOUE Tohru
Center for Biological Safety and Research
-
Kitamura Y
Division Of Pathology National Institute Of Health Sciences
-
Kurokawa Y
Division Of Toxicology National Institute Of Health Sciences
-
Sakemi Kazue
Division Of Pharmacology National Institute Of Health Sciences
-
TANIMURA Akio
Showa Women's University
-
Inoue Tohru
Division Of Toxicol. Mutagen. Nihs
-
Tanimura Akio
Showa Women's University
-
Tanimura Akio
Showa Woman's University
-
Kai Sachie
Showa Women's University
-
Hasegawa Ryuich
Division Of Toxicology National Institute Of Health Sciences
-
Hasegawa Ryuichi
Division Of Medical Safety Science
-
Hasegawa Ryuichi
Department Of Intensive Care Medicine Tohoku University Hospital
-
Unno Takashi
Division Of Pathology National Institute Of Health Sciences
-
Umemura Takashi
Division Of Pathology National Institute Of Health Science
-
Kai Sachie
Showa Women's University
-
Unno Takashi
Japan Pharmaceutical Manufactures Association (jpma):kanebo Ltd
-
Inoue Tohru
Division Of Cellular And Molecular Toxicology Center For Biological Safety And Research National Ins
-
Inoue Tohru
Division Of Cellular & Molecular Toxicology Center For Biological Safety Research National Insti
関連論文
- Serum level of expressed in renal carcinoma (ERC)/ mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT)
- Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation
- Rapid Screening for Chemopreventive Agents in Herbal Extracts in a PhIP Rat Model with DNA Adduct and Cell Proliferation as End-Points
- DNA Adduct Formation, Nucleolar Segregation and Cell Proliferation in Rats Treated with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Catechol enhanced mice hepatotoxicity treated with acetaminophen(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Lack of Initiating Activity of Kojic Acid on Hepatocarcinogenesis in F344 Rats
- P8-27 Susceptibility to pentachlorophenol, a mouse liver carcinogen in Nrf2-deficient mice(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- P6-43 Screening of chemopreventive agents using a medium-term pancreas carcinogenesis model in hamsters(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate
- Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl) nitrosamine in rats after initiation
- A possible role of oxidative stress in potassium bromate (KBrO_3) carcinogenesis (ACTIVE OXYGEN) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl) nitrosamine
- Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis : Results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- In vivo Approaches to Study Mechanism of Action of Genotoxic Carcinogens
- Mechanistic study on hepatocarcinogenesis induced by dicyclanil in mice : possible involvement of oxidative stress(Proceedings of the 32nd Annual Meeting)
- The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Prevention by 2-Mercaptoethane Sulfonate and N-Acetylcysteine of Renal Oxidative Damage in Rats Treated with Ferric Nitrilotriacetate
- 3A-08 A Chronic Inhalation Study of p-Dichlorobenzene in the F344 Rat
- "C-1 Reproductive and Developmental Toxicity Studies of Toluene. : II. Effects of inhalation exposure on fertility in rats.
- Reproductive and Developmental Toxicity Studies of Toluene.I.Teratogenicity Study of Inhalation Exposure in Pregnant Rats.
- REPRODUCTIVE AND DEVELOPMENTAL TOXICITY STUDIES OF TOLUENE I. TERATOGENICITY STUDY OF INHALATION EXPOSURE IN PREGNANT RATS
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- A SURVEY OF THE VALUES OF CLINICAL CHEMISTRY PARAMETERS OBTAINED FOR A COMMON RAT BLOOD SAMPLE IN NINETY-EIGHT JAPANESE LABORATORIES
- Comparison of the early gene responses of Ahr-activating chemicals using the Percellome system(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- The development of Chemical Toxicogenomics Database by the "Percellome" system for the mechanism-based toxicology(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- Toxicity study of Garcinia cambogia extract (3) : Testicular toxicity of Hydroxycitric acid in mice(General toxicity, Proceedings of the 32nd Annual Meeting)
- Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
- Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice
- "POINTS TO CONSIDER" REGARDING SAFETY ASSESSMENT OF BIOTECHNOLOGY-DERIVED PHARMACEUTICALS IN NON-CLINICAL STUDIES (ENGLISH TRANSLATION)
- "P-22 A Combination Toxicity Study of Sodium Ascorbate and Sodium Nitrite In Rats
- Letter to the Editor
- Response to Letter to the Editor(2)
- Response to Letter to the Editor(1)
- Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
- Effects of Oseltamivir Phosphate (Tamiflu) and Its Metabolite (GS4071) on Monoamine Neurotransmission in the Rat Brain(Communications to the Editor)
- ASSESSMENT OF QUANTITATIVE DUAL-PARAMETER FLOW CYTOMETRIC ANALYSIS FOR THE EVALUATION OF TESTICULAR TOXICITY USING CYCLOPHOSPHAMIDE -AND ETHINYLESTRADIOL- TREATED RATS
- O10-14 The Assessment of Dual Parameter Flow Cytometry Analysis to Detect the Testicular Toxicity Caused with Adriamcycin and Ethynylestradiol in Rats.
- Construction of Model Mice which Have Humanized Immune System.
- Construction of Model Mice Which Have Humanized Immune System
- Increase in in utero exposure to a migrant, 4,4'-butylidenebis(6-t-butyl-m-cresol), from nitrile-butadiene rubber gloves on brain aromatase activity in male rats
- Endocrine Disruptive Effects of Chemicals Eluted from Nitrile-Butadiene Rubber Gloves Using Reporter Gene Assay Systems(Molecular and Cell Biology)
- In Vitro Screening Assay for Detecting Aromatase Activity Using Rat Ovarian Microsomes and Estrone ELISA(Biochemistry)
- In Vitro Screening of Psychoactive Drugs by [^S]GTPγS Binding in Rat Brain Membranes(Pharmacology)
- Androgenic and Antiandrogenic Effects of Alkylphenols and Parabens Assessed Using the Reporter Gene Assay with Stably Transfected CHO-K1 Cells (AR-EcoScreen System)
- TOXICITY STUDY OF A RUBBER ANTIOXIDANT, 2-MERCAPTOBENZIMIDAZOLE, BY REPEATED ORAL ADMINISTRATION TO RATS
- 2A-13 Reproductive and Developmental Toxicity Studies of Toluene. III. Prenatal and postnatal study by inhalation exposure in rats.
- Left Ventricular Apical Thrombus Formation in a Patient With Suspected Tako-Tsubo-Like Left Ventricular Dysfunction
- A 13-WEEK TOXICITY STUDY OF SIMULTANEOUS ADMINISTRATION OF COCHINEAL AND ALUMINUM POTASSIUM SULFATE IN RATS
- Impaired Myelinogenesis and Early Maturation of Oligodendrocytes in Black Tremor Hamster with Central Nervous System Myelin Deficiency
- Sustained hypomyelination and high serum thyroid hormone in aged black tremor hamster
- ACUTE, SUBCHRONIC AND CHRONIC TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-ISOBUTYLIDENEBIS (4,6-DIMETHYLPHENOL) IN RATS
- Analysis of the effect of dietary phytoestrogens on the gene expression profiles of endocrine disruptors using the "Percellome" system(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- P7-35 Three-months dietary toxicity study of o-cymen-5-ol(biosol) in rats : Biosol induced renal injury and thymocyte apoptosis(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Toxicity study of Garcinia cambogia extract II : A28-day dietary exposure of hydroxycitric acid, a principal ingredient of Garcinia cambogia extract, on testicular toxicity in rats. (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings
- Toxicity study of Garcinia canbogia extract I : A 52-week-toxicity study of Garcinia cambogia extract in rats (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- "P-12 The effects of 90-day feeding of Aramite or other herbicides of diphenyl ether group on livers, gall-bladders and bile ducts in dogs.
- Effects of granulocyte-colony stimulatig factor in newborn rats.
- Sample surveillance for clinical pathology testing.
- ACUTE, SUBCHRONIC AND CHRONIC TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-METHYLENEBIS(4-METHYL-6-TERT-BUTYLPHENOL) IN RATS
- Intrauterine environment-genome interaction and Children's development (2) : Brain structure impairment and behavioral disturbance induced in male mice offspring by a single intraperitoneal administration of domoic acid (DA) to their dams
- Gene expression profiling of a gene-targeted mouse embryo using the "Percellome" system as a model for molecular developmental toxicity(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- B-22 A 28-DAY REPEATED DOSE TOXICITY TEST AND THE TIME COURSE OF CHOLINESTERASE ACTIVITY TEST FOR CHLORPYRIFOS IN WISTAR RAT
- B38 COMPARISON OF TOXICITY OF p-DCB IN MALE AND FEMALE RATS
- "P-35 Contribution of Oxidative Stress to Rat Hepatotoxicity induced by 2-Nitropropane : Lipid Peroxidation and Inhibitory Effect of Green Tea.
- COMRARISON OF TOXICITY OF p-DICHLOROBENZENE (p-DCB) GIVEN ORALLY AND BY INHALATION
- O-55 HEMATOTOXICICOLOGIC CHARACTERISTICS FOR OXIDATIVE STRESSES INTRANSGENIC AND/OR KNOCK-OUT MICE FOR THIOREDOXIN/ADF GENE.(Proceedings of the 27th Annual Meeting)
- 21B-10-4 Benzene hemopoietic toxicity revisited- a new concept.
- 3A-09 Hemopoietic Stem-Cell Kinetics Evaluated by Bromodeoxyuridine Incorporation Followed by Near-UV Exposure to Kill Cycling Stem Cells (BUUV). 2) Bone Marrow Cells from Mice Carrying Human c-myc Proto-Oncogene with Promoters Combined with Immunoglobuli
- "P-8 Experimental myelodysplasia induced by Azidothymidine (AZT) : Hemopoietic Stem Cell Kinetics And Pathological Findings.
- Sample surveillance for clinical pathology testing(2) Analysis of blood chemical data
- 28-DAY REPEATED-DOSE ORAL TOXICITY STUDY OF 2-MERCAPTOBENZIMIDAZOLE, A RUBBER ANTIOXIDANT, IN RATS
- A 14-WEEK ORAL TOXICITY STUDY OF TRIBUTOXYETHYL PHOSPHATE(TBEP) IN RATS
- Uterine Carcinosarcoma in a 2-year-old Female Wistar Hannover GALAS Rat
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- Intracoronary Administration of Nicorandil for the Treatment of Spontaneous Microvascular Spasm With ST Segment Elevation
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Chronic cadmium treatment induces islet B cell injury in ovariectomized cynomolgus monkeys
- P10-16 Increased osteoid volume and iron deposition of the Iumbar vertebra in a chronic cadmium toxicosis model of cynomolgus monkeys.
- 21D-04-1 Quantitative Analysis of Bone Lesion in Ovariectomized Cynomolgus Monkeys Given Repeated Intravenous Injections of CdCl_2.
- Comparison of Antibody Titers in Rabbits Following Immunization with Inactivated Influenza Virus via Subarachnoidal or Subcutaneous Route
- Efficacy of Intracerebral Immunization against Pseudorabies Virus in Mice
- In vitro demonstration of neural transmission of avian influenza A virus
- Laboratory of Comparative Pathology
- The Effects of a Vitamin D-deficient Diet on Chronic Cadmium Exposure in Rats
- ACUTE TOXICITY OF CADMIUM IN RATS WITH OR WITHOUT CADMIUM PRETREATMENT
- 302 EFFECTS OF CADMIUM CHLORIDB ON THE BLOOD AND URINARY EXAMINATIONS IN OVARIECTOMIZED RATS
- Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency
- In vivo genotoxicity of 1-methylnaphthalene from comprehensive toxicity studies with B6C3F1 gpt delta mice
- Uterine Carcinosarcoma in a 2-year-old Female Wistar Hannover GALAS Rat
- Reporter gene mutation in the livers of gpt delta mice treated with 5-(hydroxymethyl)-2-furfural, a contaminant of various foods
- Molecular mechanisms underlying ochratoxin A-induced genotoxicity : global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression