2A-13 Reproductive and Developmental Toxicity Studies of Toluene. III. Prenatal and postnatal study by inhalation exposure in rats.
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1997-10-15
著者
-
Suzuki Sachiko
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Hirose Akihiko
Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Science
-
KANEKO Toyozo
Division of Cellular and Molecular Toxicology, Kangwon National University
-
Hirose Akihiko
National Inst. Of Health Sciences
-
Kitajima Satoshi
Department Of Environmental Health And Toxicology Tokyo Metropolitan Institute Of Public Health
-
Satoh Kanako
東京都健康安全研究センター 環境保健部
-
Suzuki Shugo
名古屋市立大学 医学研究科実験病態病理学分野
-
Sai-kato Kimie
Division Of Toxicology
-
KAWASAKI Yasushi
Div of Cellular and Molecular Toxicology
-
KANEKO Toyozo
National Center for Drug Safety Evaluation
-
Hirose Akihiko
Division Of Risk Assessment Biological Safety Research Center National Institute Of Health Sciences
-
INOUE Tohru
Division of Toxicology
-
KUROKAWA Yuji
Division of Toxicology
-
Ono Atsushi
Division of Toxicology, National Institute of Health Sciences
-
Sekita Kiyoshi
Division of Toxicology, National Institute of Health Sciences
-
Ogawa Yukio
Division of Toxicology, National Institute of Health Sciences
-
Saito Minoru
Division of Toxicology, National Institute of Health Sciences
-
Naito Katsushi
Division of Toxicology, National Institute of Health Sciences
-
Furuya Tsuyoshi
Division of Toxicology, National Institute of Health Sciences
-
Matsumoto Kiyoshi
Institute of Experimental Animals, Shinshu University School of Medicine
-
Tanaka Satoru
Division of Toxicology, National Institute of Health Sciences
-
Sekita Kiyoshi
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
TANAKA Satoru
Toxicology Laboratory, Kissei Pharmaceutical Co., Ltd.
-
INOUE Tohru
Center for Biological Safety and Research
-
Kitamura Y
Division Of Pathology National Institute Of Health Sciences
-
Hirose Akihiko
Division Of Risk Assessment National Institute Of Health Sciences
-
Kurokawa Y
Division Of Toxicology National Institute Of Health Sciences
-
Ogawa Yumie
Fuji Gotemba Research Labs. Chugai Pharm. Co. Ltd.
-
Ono Atsushi
Toxicogenomics Project National Institute Of Biomedical Innovation:national Institute Of Health Scie
-
Ono Atsushi
Biological Safety Research Center National Institute Of Health Science
-
Saito Minoru
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
Saito Masako
Department Of Applied Physics University Of Tokyo:(present Address)institute For Solid State Physics
-
Inoue Tohru
Division Of Toxicol. Mutagen. Nihs
-
Tanaka Satoru
Division Of Pharmacology National Institute Of Hygienic Sciences
-
Hirose Akihiko
Division Of Toxicology National Institute Of Health Sciences
-
SATO Michio
Div. of Medical Devices National Institute of Hygienic Sciences
-
FURUYA Tsuyoshi
Biological Safety Research Center, National Institute of Health Science
-
Kodama Y
Biological Safety Research Center National Institute Of Health Science
-
Ogawa Yukio
Fuji Gotemba Research Labs. Chugai Pharm. Co. Ltd.
-
Sugi M
Toin Univ. Yokohama Yokohama Jpn
-
Naito Katsushi
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
Naitoh Katsusi
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Kaneko Toyozo
Division Of Cellular And Molecular Toxicology Kangwon National University
-
Kaneko Toyozo
Dlv. Of Toxicology Biological Safety Reseach Center National Institute Of Hygienic Sciences
-
Tanaka S
Toxicology Laboratory Kissei Pharmaceutical Co. Ltd.
-
Kaneko Toyozo
Division Of Cellular & Molecular Toxicology Center For Biological Safety Research National Insti
-
Kaneko T
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Hirose Akihiko
National Inst. Of Health Sciences (nihs)
-
Tanaka Satoru
Division Of Internal Medicine Shizuoka City Hospital
-
Shigeno M
Sii Nanotechnology Inc.
-
Furuya Tsuyoshi
Biological Safety Research Center National Institute Of Health Science
-
Naito K
Division Of Toxicology Biological Safety Research Center National Institute Of Health Sciences
-
Ono Atsushi
Division Of Cellular & Molecular Toxicology National Institute Of Health Sciences
-
Matsumoto Kiyoshi
Institute Of Experimental Animals Shinshu Univ.sch Of Med.
-
Inoue Tohru
Division Of Cellular And Molecular Toxicology Center For Biological Safety And Research National Ins
-
Ando Hiroshi
Department Of Environmental Health And Toxicology Tokyo Metropolitan Institute Of Public Health
-
Takayama Satoshi
Research Department Saitama Daiichi Pharmaceutical Co. Ltd. Japanese Pharmaceutical Manufacturers As
-
Tanaka Satoru
Division Of Internal Medicine And Thoracic Surgery Shizuoka City Hospital
-
Inoue Tohru
Division Of Cellular & Molecular Toxicology Center For Biological Safety Research National Insti
-
Hirose Akihiko
Division Of Risk Assessment Biological Safely Research Center National Institute Of Health Sciences
-
Takayama Satoshi
Research Department Saitama Daiichi Pharmaceutical Co. Ltd. Japanese Pharmaceutical Manufacturers Association
-
OGAWA Yukio
Division of Cellular and Molecular Toxicology, Biological Safety Research Center, National Institute of Health Sciences
関連論文
- Effects of preparation methods for multi-wall carbon nanotube (MWCNT) suspensions on MWCNT induced rat pulmonary toxicity
- Serum level of expressed in renal carcinoma (ERC)/ mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT)
- Relation between statistics and treatment-related changes obtained from toxicity studies in rats : if detected a significant difference in low or middle dose for quantitative values, this change is considered as incidental change?
- Electron Microscopical Evidence of the Protective Function of Thioredoxin (TRX/ADF) Transgene against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced Cellular Toxicity in the Liver and Brain
- Enigma of oxidative stress in benzene induced hematotoxicity answered by thioredoxin-overexpression mouse(Blood, Biomarker, Proceedings of the 32nd Annual Meeting)
- Prevention by 2-Mercaptoethane Sulfonate and N-Acetylcysteine of Renal Oxidative Damage in Rats Treated with Ferric Nitrilotriacetate
- Evaluation of developmental toxicity of UV stabilizer 2-(3', 5'-di-tert-butyl-2'-hydroxyphenyl)-5-chlorobenzotriazole in rats(Development, Reproduction, Proceedings of the 32nd Annual Meeting)
- Effects of progesterone on implantation failure induced by dibutyltin dichloride in rats (DEVELOPMENT AND REPRODUCTION) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- 3A-11 Effects of a peroxisome proliferator on DNA damage inducible-gene products induced by methyl methane sulfonate (MMS) in the primary hepatocytes culture of the rat
- 3A-08 A Chronic Inhalation Study of p-Dichlorobenzene in the F344 Rat
- "C-1 Reproductive and Developmental Toxicity Studies of Toluene. : II. Effects of inhalation exposure on fertility in rats.
- Reproductive and Developmental Toxicity Studies of Toluene.I.Teratogenicity Study of Inhalation Exposure in Pregnant Rats.
- REPRODUCTIVE AND DEVELOPMENTAL TOXICITY STUDIES OF TOLUENE I. TERATOGENICITY STUDY OF INHALATION EXPOSURE IN PREGNANT RATS
- THE TOXICITY STUDY OF BIODEGRADABLE PLASTIC IN RATS BY DIETARY ADMINISTRATION
- TWENTY-EIGHT-DAY REPEATED DOSE TOXICITY TESTS OF O-NITROTOLUENE IN WISTAR RATS
- ACUTE INHALATION TOXICITY TESTS OF DICHLOROSILANE AND TETRAFLUOROSILANE(THE SPECIALTY GASES)
- 306 A 28-DAY REPEATED DOSE TOXICITY TEST OF EUROPIUM AND GADORINIUM IN WISTAR RAT IN COMPARISON WITH LANTHANUM AND YTTRIUM
- 407 A 28-DAY REPEATED DOSE TOXICITY TEST OF LANTHANUM AND YTTRIUM IN WISTAR RAT
- 206 A 28-DAY REPEATED INHALATION TOXICITY TEST OF 2,2,3,3,3-PENTAFLUOROPROPANOL IN F344 RAT
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- A SURVEY OF THE VALUES OF CLINICAL CHEMISTRY PARAMETERS OBTAINED FOR A COMMON RAT BLOOD SAMPLE IN NINETY-EIGHT JAPANESE LABORATORIES
- Comparison of the early gene responses of Ahr-activating chemicals using the Percellome system(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- The development of Chemical Toxicogenomics Database by the "Percellome" system for the mechanism-based toxicology(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
- Toxicity study of Garcinia cambogia extract (3) : Testicular toxicity of Hydroxycitric acid in mice(General toxicity, Proceedings of the 32nd Annual Meeting)
- Bio-molecular model for cancer prevention : Attenuation of oxidative stress by thioredoxin over-expression to reduce the benzene leukemia (BLOOD SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Effects of preparation methods for multi-wall carbon nanotube (MWCNT) suspensions on MWCNT induced rat pulmonary toxicity
- Peroxisome Proliferators Attenuate Free Arachidonic Acid Pool in the Kidney Through Inducing Lysophospholipid Acyltransferases
- "POINTS TO CONSIDER" REGARDING SAFETY ASSESSMENT OF BIOTECHNOLOGY-DERIVED PHARMACEUTICALS IN NON-CLINICAL STUDIES (ENGLISH TRANSLATION)
- Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats
- REVISION AND ESTABLISHMENT OF JAPANESE DRINKING WATER QUALITY GUIDELINES FOR DI(2-ETHYLHEXYL) PHTHALATE, TOLUENE AND VINYL CHLORIDE : DIFFERENCES FROM THE LATEST WHO GUIDELINE DRAFTS
- Letter to the Editor
- Response to Letter to the Editor(2)
- Response to Letter to the Editor(1)
- Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube
- Effects of Oseltamivir Phosphate (Tamiflu) and Its Metabolite (GS4071) on Monoamine Neurotransmission in the Rat Brain(Communications to the Editor)
- ASSESSMENT OF QUANTITATIVE DUAL-PARAMETER FLOW CYTOMETRIC ANALYSIS FOR THE EVALUATION OF TESTICULAR TOXICITY USING CYCLOPHOSPHAMIDE -AND ETHINYLESTRADIOL- TREATED RATS
- O10-14 The Assessment of Dual Parameter Flow Cytometry Analysis to Detect the Testicular Toxicity Caused with Adriamcycin and Ethynylestradiol in Rats.
- Construction of Model Mice which Have Humanized Immune System.
- Construction of Model Mice Which Have Humanized Immune System
- Increase in in utero exposure to a migrant, 4,4'-butylidenebis(6-t-butyl-m-cresol), from nitrile-butadiene rubber gloves on brain aromatase activity in male rats
- Endocrine Disruptive Effects of Chemicals Eluted from Nitrile-Butadiene Rubber Gloves Using Reporter Gene Assay Systems(Molecular and Cell Biology)
- In Vitro Screening Assay for Detecting Aromatase Activity Using Rat Ovarian Microsomes and Estrone ELISA(Biochemistry)
- In Vitro Screening of Psychoactive Drugs by [^S]GTPγS Binding in Rat Brain Membranes(Pharmacology)
- Androgenic and Antiandrogenic Effects of Alkylphenols and Parabens Assessed Using the Reporter Gene Assay with Stably Transfected CHO-K1 Cells (AR-EcoScreen System)
- TOXICITY STUDY OF A RUBBER ANTIOXIDANT, 2-MERCAPTOBENZIMIDAZOLE, BY REPEATED ORAL ADMINISTRATION TO RATS
- 2A-13 Reproductive and Developmental Toxicity Studies of Toluene. III. Prenatal and postnatal study by inhalation exposure in rats.
- A 13-WEEK TOXICITY STUDY OF SIMULTANEOUS ADMINISTRATION OF COCHINEAL AND ALUMINUM POTASSIUM SULFATE IN RATS
- ACUTE, SUBCHRONIC AND CHRONIC TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-ISOBUTYLIDENEBIS (4,6-DIMETHYLPHENOL) IN RATS
- RESULTS OF A 28-MONTH CHRONIC INHALATION TOXICITY STUDY OF FORMALDEHYDE IN MALE FISHER-344 RATS
- "P-27 Local irritation effects in the nasal cavity and the nasopharyngeal epithelia of the rat treated per os for 10 days with repeated doses of N-(fluorodichloromethylthio) phthalimide ("fluor-folpet").
- CHRONIC ORAL TOXICITY STUDY OF A SYNTHETIC ANTIOXIDANT, 2, 2'-METHYLENEBIS(4-ETHYL-6-TERT-BUTYLPHENOL)(MBEBP)IN RATS
- TOXICITY STUDIES OF A SYNTHETIC ANTIOXIDANT, 2,2'-METHYLENEBIS (4-ETHYL-6-TERT-BUTYLPHENOL) IN RATS 1. ACUTE AND SUBCHRONIC TOXICITY
- B-30 STUDY ON ESSENYIAL METAL CONCENTRATION IN THE ORGANS OF RATS
- B-22 A 28-DAY REPEATED DOSE TOXICITY TEST AND THE TIME COURSE OF CHOLINESTERASE ACTIVITY TEST FOR CHLORPYRIFOS IN WISTAR RAT
- C07 TOXICITY OF 2-MERCAPTOBENZOTHIAZOLE(MBT) IN MICE
- C06 TOXICOLOGICAL STUDY ON 2-(4-MORPHOLINOTHIO)BENZOTHIAZOLE (2-MTBT) IN MICE
- B38 COMPARISON OF TOXICITY OF p-DCB IN MALE AND FEMALE RATS
- STUDY ON THE TOXICITY OF 2,2'-METHYLENE-bis(4-ETHYL-6-tert-BUTYLPHENOL) IN RAT (NO.1)
- CHRONIC TOXICITY STUDY OF 2-MERCAPTOIMIDAZOLINE (2-MIZ) IN MICE
- "C-5 Validation of alternatives to eye irritation tests for cosmetic ingredients (Results of the first, second, and third validation).
- Metabolism of 2,2,3,3,3-Pentafluoropropanol (5-FP) in Rats (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- COMRARISON OF TOXICITY OF p-DICHLOROBENZENE (p-DCB) GIVEN ORALLY AND BY INHALATION
- TOXICITY OF 2-MERCAPTOIMIDAZOLINE (2-MIZ) (2ND REPORT) SUBACUTE TOXICITY IN MICE
- P12-03 Is Nrf2 gene Involved in benzene metabolic pathway?
- O-55 HEMATOTOXICICOLOGIC CHARACTERISTICS FOR OXIDATIVE STRESSES INTRANSGENIC AND/OR KNOCK-OUT MICE FOR THIOREDOXIN/ADF GENE.(Proceedings of the 27th Annual Meeting)
- 21B-10-4 Benzene hemopoietic toxicity revisited- a new concept.
- 3A-09 Hemopoietic Stem-Cell Kinetics Evaluated by Bromodeoxyuridine Incorporation Followed by Near-UV Exposure to Kill Cycling Stem Cells (BUUV). 2) Bone Marrow Cells from Mice Carrying Human c-myc Proto-Oncogene with Promoters Combined with Immunoglobuli
- TOXICITY OF ORIENTAL BEZOAR AND ITS COMPONENTS
- SEMI-QUANTITATIVE IMMUNOHISTOCHEMICAL ANALYSIS OF MALE RAT-SPECIFIC α_2u-GLOBULIN ACCUMULATION FOR CHEMICAL TOXICITY EVALUATION
- Risk assessment for the endocrine distruption effects by bisphenol A (DEVELOPMENT AND REPRODUCTION) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- P10-17 Risk assessment for formaldehyde in drinking water via oral and inhalation exposure.
- P-75 Toxicity evaluation of a strong mutagen MX (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone) in drinking water.(Proceedings of the 27th Annual Meeting)
- TOXICOLOGICAL EFFECTS OF SOME INHALED CHEMICALS ON THE RESPIRATORY TRACT AND THE LUNGS OF RATS (2nd report)
- TOXICOLOGICAL EFFECTS OF SOME INHALED CHEMICALS ON THE RESPIRATORY TRACT AND THE LUNGS OF RATS (first report)
- TOXICITY OF 2-MERCAPTOIMIDAZOLINE (2-MIZ) III TRANSFER THROUGH THE MATERNAL MILK AND EFFECT OF 2-MIZ TO THE OFFSPRING MICE
- TOXICITY OF 2-MERCAPTOIMIDAZOLINE (2-MIZ) (1ST REPORT) ACUTE TOXICITY AND IMMUNOTOXICITY OF 2-MIZ IN MICE
- Subcellular Distribution of Rat Liver NADPH-2,4-Dienoyl-CoA Reductase
- STUDIES ON DAIZE EYE IRRITATION TEST AND CORRELATION TO HISTOPATHOLOGICAL FINDINGS
- Principles of risk assessment for determining the safety of chemicals : Recent assessment of residual solvents in drugs and di(2-ethylhexyl) phthalate
- Disappearance of gender-related difference in the toxicity of benzotriazole ultraviolet absorber in juvenile rats
- Placental-transfer of tetrabromobisphenol A in mice(Development, Reproduction, Proceedings of the 32nd Annual Meeting)
- EFFECTS OF TCDD ON THE GENE EXPRESSION IN MOUSE EMBRYONIC STEM CELLS IN CULTURE.(GENERAL SESSION BY POSTER PRESENTATION)(DEVELOPMENT AND REPRODUCTION)
- EFFECTS OF METYRAPONE ON PLASMA CORTICOSTERONE LEVELS AND INCIDENCE OF CLEFT PALATE IN PREGNANT ddY-Slc MICE FED POLYCHLORINATED TERPHENYLS
- INHALATION TOXICITY STUDY OF FORMALDEHYDE (NASAL CAVITY CANCER OF RATS)
- Influence of coefficient of variation in determining significant difference of quantitative values obtained from 28-day repeated-dose toxicity studies in rats
- Fullerene (C_) Is Negative in the In Vivo Pig-A Gene Mutation Assay
- Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats
- WI-05 Future Perspective of Safety Evaluation on Biotechnology-derived Pharmaceutical Products.
- Report 3 : BIOTECHNOLOGY PRODUCTS : SPECIFIC ISSUES AND ICH S6 (Safety assessment of biotechnology-derived pharmaceutical product.)
- Toxicological bases for micro-dose study(Toxicological Bases for Micro-dose Study, Proceedings of the 32nd Annual Meeting)
- Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats
- Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice
- Teratogenicity of multi-wall carbon nanotube (MWCNT) in ICR mice
- Determination of dose dependence in repeated dose toxicity studies when mid-dose alone is insignificant
- Repeated dose and reproductive/developmental toxicity of perfluorooctadecanoic acid in rats
- No toxicological effects on acute and repeated oral gavage doses of single-wall or multi-wall carbon nanotube in rats
- Sub-acute oral toxicity study with fullerene C60 in rats
- A 90-day Feeding Toxicity Study of L-Serine in Male and Female Fischer 344 Rats
- P-061(O-9) Using Existing In Vitro Structural Alters For Chromosome Damage To Predict In Vivo Activity And Direct Future Testing(Poster presentation)