Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
スポンサーリンク
概要
- 論文の詳細を見る
- 2002-10-30
著者
-
小西 陽一
奈良県立医科大学腫瘍病理
-
Hirose Masao
Division of Pathology, National Institute of Health Sciences
-
小西 陽一
奈良医大
-
高橋 通正
(独)産業技術総合研究所 環境管理技術研究部門
-
NAKAE Dai
Department of Environmental Health and Toxicology, Tokyo Metropolitan Institute of Public Health
-
Mori H
Division Of Pathology National Institute Of Health Sciences
-
Inada Ken-ichi
Department Of Pathology Fujita Health University School Of Medicine
-
FURUKAWA Fumio
Division of Pathology, National Institute of Health Sciences
-
Nakae D
Department Of Environmental Health And Toxicology Tokyo Metropolitan Institute Of Public Health:toky
-
Nakae D
Department Of Pathology Sasaki Institute Sasaki Foundation
-
Nakae Dai
Department Of Environmental Health And Toxicology Tokyo Metropolitan Institute Of Public Health
-
Tsukamoto T
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
TSUKAMOTO Tetsuya
Division of Oncological Pathology, Aichi Cancer Center Research Institute
-
TATEMATSU Masae
Division of Oncological Pathology, Aichi Cancer Center Research Institute
-
TOTSUKA Yukari
Cancer Prevention Division, National Cancer Center Research Institute
-
WAKABAYASHI Keiji
Cancer Prevention Division, National Cancer Center Research Institute
-
FUKUSHIMA Shoji
Department of Pathology, Osaka City University Medical School
-
WANIBUCHI Hideki
Department of Pathology, Osaka City University Medical School
-
MORIMURA Keiichirou
Department of Pathology, Osaka City University Medical School
-
WEI Min
Department of Pathology, Osaka City University Medical School
-
KONISHI Yoichi
Department of Oncological Pathology, Cancer Center, Nara Medical University
-
TSUDA Hiroyuki
Experimental Pathology and Chemotherapy Division, National Cancer Center Research Institute
-
UEHARA Nobuaki
Experimental Pathology and Chemotherapy Division, National Cancer Center Research Institute
-
IMAIDA katsumi
Department of Pathology, Nagoya City University Medical School
-
SHIRAI Tomoyuki
Department of Pathology, Nagoya City University Medical School
-
IMAIDA Katsumi
Onco-Pathology, Faculty of Medicine, Department of Pathology and Host-Defense, Kagawa University
-
Imaida K
Onco-pathology Faculty Of Medicine Department Of Pathology And Host-defense Kagawa University
-
Imaida Katsumi
国立がんセンター研究所 がん予防基礎研究プロジェクト
-
Imaida Katsumi
大雄会医科学研究所
-
Imaida Katsumi
Department Of Onco-pathology Faculty Of Medicine Kagawa University
-
Konishi Y
Department Of Oncological Pathology Cancer Center Nara Medical University
-
Konishi Yoichi
奈良県立医科大学附属がんセンター 腫瘍病理学
-
Takahashi M
National Inst. Health Sci. Tokyo
-
Wanibuchi Hideki
Department Of Pathology Osaka City University Medical School
-
Wanibuchi Hideki
大阪府立成人病センター 分子生物学
-
Wei Min
Department Of Pathology Osaka City University Medical School
-
Furukawa F
Division Of Pathology National Institute Of Health Sciences
-
Furukawa Fumio
国立衛生試験所
-
Furukawa Fumio
Division Of Pathology National Institute Of Health Sciences
-
Morimura K
Department Of Pathology Osaka City University Medical School
-
Morimura Keiichirou
大阪市立大学 医学部都市医学
-
Morimura Keiichirou
Department Of Pathology Osaka City University Medical School
-
Inada Ken-ichi
愛知県がんセンター研究所 腫瘍病理学部
-
高橋 通正
神奈川県環境科セ
-
Makita Hiroki
岐阜大学 第1病理
-
稲田 健一
Department Of Pathology Fujita Health University School Of Medicine
-
Wakabayashi Keiji
Cancer Prevention Basic Research Project National Cancer Center Research Institute
-
Uehara Nobuaki
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Yanai T
Department Of Veterinary Pathology Gifu University
-
Totsuka Yukari
大阪府立大学先端科学イノベーションセンター 遺伝子環境科学研究室
-
Totsuka Y
Cancer Prevention Basic Research Project
-
Totsuka Yukari
Cancer Prevention Basic Research Project National Cancer Center Research Institute
-
Tatematsu Masae
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Tsukamoto Tetsuya
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Konishi Yoichi
International Federation Of Societies Of Toxicologic Pathologists
-
Hirose Masao
Division Of Pathology National Institute Of Health Sciences
-
Fujiwara Yushi
Department Of Surgery Osaka City Juso Hospital
-
Hirota M
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
-
Kitayama Wakashi
Department Of Oncological Pathology Cancer Center Nara Medical University
-
Tanaka Harunari
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Tsuda Hiroyuki
First Department Of Pathology Nagoya City University Medical School
-
Tsuda Hiroyuki
Department Of Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
-
Tsuda H
Keio Univ. Yokohama‐shi Jpn
-
Tsuda Hiroyuki
Department Of Molecular Toxicology Nagoya City University
-
Tsuda Hiroyuki
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Konishi Yoichi
Department Of Gastroenterology And Hepatology Shimane University School Of Medicine
-
小西 陽一
奈良医大附属病院がんセンター病理
-
SHIRAI Tomoyuki
Nagoya City University Medical School
-
Yamachika Takasuke
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Kobayashi Y
International Federation Of Societies Of Toxicologic Pathologists
-
Wanibuchi H
Department Of Pathology Osaka City University Medical School
-
Takaoka Masaya
Medicinal Safety Research Laboratories Daiichi-sankyo Co. Ltd.
-
Fukushima Shoji
中央労働災害防止協会日本バイオアッセイ研究センター
-
Wei Min
Department Of Food Science Obihiro University Of Agriculture And Veterinary Medicine
-
Wakabayashi Keiji
愛知県がんセンター研究所
-
Toriyama‐baba H
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Tsukamoto Takahisa
First Department Of Oral And Maxillofacial Surgery School Of Dentistry
-
Nakae Dai
Department Of Oncologic Pathology Cancer Center Nara Medical University
-
Hirose Masao
First Department Of Pathology Nagoya City University Medical School
-
Tanaka H
Department Of Cancer Control And Statistics Osaka Medical Center For Cancer And Cardiovascular Disea
-
Tsuda Hiroyuki
Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
-
Shirai Tomoyuki
Department Of Biochemistry Niigata College Of Pharmacy
-
Tsuda H
Department Of Obstrics And Gvnecology Toyama Medical And Pharmaceutical University
-
Fukushima Shoji
Dept. Pathol. Osaka City University Medical School
-
Tsuda Hitoshi
Member Of The Research Group Japanese Breast Cancer Society
-
Tsukamoto Takahisa
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Tsuda H
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Fukushima Shoji
Department Of Pathology Osaka City University Medical School
-
Tsuda H
Department Of Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
-
Yoshida Katsunori
Department Of Urology Nara Prefectural Mimuro Hospital
-
Tsuda Hiroyuki
Dep. Of Molecular Toxicology Nagoya City Univ.
-
Wakabayashi K
Cancer Prevention Basic Research Project National Cancer Center Research Institute
-
Tsukamoto T
Department Of Public Health Osaka City University Graduate School Of Medicine
-
Wakabayashi Keiji
Department Of Food & Nutritional Science Graduate School Of Nutrition & Environmental Scienc
-
Konishi Yoichi
Oklahoma Medical Research Foundation
-
Fukuhara Kennichirou
Department Of Gastroenterological Surgery Osaka City University Graduate School Of Medicine
-
Totsuka Yukari
国立がん研究センター研究所 発がんシステム研究分野
-
Min Wei
Department Of Pathology Osaka City University Medical School
-
Fukushima Shoji
Department Of Gastroenterological Surgery Osaka City University Graduate School Of Medicine
-
Kaneko Y
Department Of Urology Nara Prefectural Mimuro Hospital
-
Takahashi Masahide
Departments Of Pathology Nagoya University Graduate School Of Medicine
-
Wanibuchi Hideki
Department Of Pathology Osaka City University Graduate School Of Medicine
関連論文
- ラット骨肉腫および悪性線維性組織球腫細胞におけるTGFβisoform発現とTGFβsignaling pathwayの変異の有無
- ラット骨肉腫細胞における野生型p53癌抑制遺伝子導入の細胞増殖および遺伝子発現に対する効果
- ラット可移植性骨肉腫自然肺転移モデルにおける新規MMP阻害剤OPB-3206による肺転移抑制作用
- ラット可移植性骨肉腫自然肺転移モデルにおけるテロメラーゼ活性の増強
- 6 肝細胞癌におけるテロメアDNAの短縮 : 腫瘍の発育・脱分化との関連(第48回日本消化器外科学会総会)
- WistarラットのおけるN-ニトロソビス(2-ハイドロキシプロピル)アミンの分布, 代謝及び排泄
- 多彩な呼吸器感染症と耐性結核症を合併したエイズの一剖検例
- 205 胆道系悪性腫瘍における Ki-ras 遺伝子変異の検索(第46回日本消化器外科学会)
- 68.縦隔腫瘍が疑われた高分化胎児型肺腺癌の1例
- COX-2選択的阻害剤によるラット表在性膀胱癌の発育抑制
- 粘液産生性の膵腫瘍をめぐる諸問題 : 病理からの提言
- 9.ラットにおけるコリン欠乏アミノ酸食による肝細胞死・再生・ 線維化より発癌に至る内因性機構の解析
- O-5 発癌感受性の異なる近交系ラットの交配によるF2ラットにおける発癌耐性の分布
- 実験的肝細胞癌の発生に関する研究の問題点
- O-83 ハムスター膵管癌発生過程におけるMMPsの関与およびMMPs阻害剤の発癌抑制
- 膵癌の多段階発癌 (特集 多段階発癌--臓器特異性と共通点)
- P-109 ラット肝に於ける3'-Me-DABによる発癌感受性と細胞増殖能
- ハムスター膵発癌モデルにおけるMMPsおよびTIMPsの発現と癌進展との関係
- 長期生存中である膵原発悪性リンパ腫の1切除例
- 膵管病変の発生部位による生物学的特性の差異(消化器癌の前癌病変 : 最近の知見より(大腸・膵))
- ラット肝癌発生系におけるテロメラーゼ活性上昇の生物学的意義(細胞の不死化とアポトーシスに関連した消化器癌研究の現況)
- ラット可移植性骨肉腫における p53, Ki-ras, およびmdm2遺伝子変異の検索
- 胃肉腫と鑑別を要した膵退形成性膵管癌の1例
- LACK OF SIGNIFICANT TUMOR INDUCTION BY ENDOGENOUSLY FORMED N-NITROSOBIS (2- HYDROXYPROPYL) AMINE IN RATS FED TRIS (2-HYDROXYPROPYL) AMINE AND SODIUM NITRITE
- ヒト泌尿器科腫瘍におけるcripto遺伝子産物の発現に関する免疫組織化学的検索
- 特異な胸壁浸潤を示した石綿肺合併肺癌の1例
- 25. N-Bis(2-hydroxypropyl)nitrosamine(DHPN)の経口投与によるラット肺癌の発生パターンについて : 第28回日本肺癌学会関西支部会
- 石綿肺合併肺癌の一手術例 : 自験症例とその文献的考察
- 検診時に発見された石綿肺肺癌の一手術例 : 関西支部 : 第34回日本肺癌学会関西支部会
- Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
- 40.胸部放射線照射同時併用化学療法(weekly Paclitaxel+Carboplatin)の経過中に間質性肺炎を発症し死亡した腺扁平上皮癌の1剖検例(第72回日本肺癌学会関西支部会)
- 61.癌性胸膜炎で発症し, 剖検にて胆管細胞癌の胸膜浸潤と診断された1例(第71回日本肺癌学会関西支部会)
- F-5 原発性非小細胞肺癌におけるTie2,angiopoietin-1,vascular endothelial growth factor,CD31の発現増強(VEGF,第40回日本肺癌学会総会号)
- 92.ラットにおけるN-bis(2-hydroxypropyl)nitrosamine(DHPN)による肺腫瘍発生に及ぼすHypophysectomy(HS)の影響(第42回日本肺癌学会関西支部会)
- 126 ラットにおけるN-bis (2hydroxypropy1) nitrosamine (DHPN)の肺腫瘍および胸膜病変におよぼす石綿(chrysotile)の役割
- ラットにおけるN-Bis(2-hydroxypropyl)Nitrosamine(DHPN)と石綿併用投与による胸膜中皮腫の発生と胸膜の変化について
- BBN誘発ラット膀胱腫瘍におけるアラキドン酸カスケードの関与
- 57.術中迅速標本で診断した気管支カルチノイドの1例(第74回日本肺癌学会関西支部会)
- 51.転移性肺腫瘍を疑わせた多発性肺腺様嚢胞癌の1例(第72回日本肺癌学会関西支部会)
- 48.小腸転移を伴った肺多形成腺癌(sarcomatoid carcinoma)の1例(第71回日本肺癌学会関西支部会)
- 膀胱腫瘍に関する実験的研究 : 第1報 N-Butyl-N-Butanol (4)-Nitrosamine 投与によるダイコクネズミの膀胱腫瘍発生について
- 52.CT下生検にて診断できた胸腺カルチノイドの1例 : 第70回日本肺癌学会関西支部会
- 56.硬化性血管腫を思わせた肺肉腫の1切除例 : 第69回日本肺癌学会関西支部会
- 63.術前高CEA血症(217ng/ml)を伴い気腫性肺嚢胞に隣接した小型肺腺癌の1切除例 : 第67回日本肺癌学会関西支部会
- 60.縦隔原発びまん性硬化性大細胞型悪性リンパ腫の1例 : 第66回日本肺癌学会関西支部会
- 12 切除肺癌の高分解能X線CT像と伸展固定標本軟X線像ならびに病理像との対比検討
- BBN誘発ラット膀胱癌におけるカロテノイドおよびNSAIDを用いた化学発癌予防
- 小型肺癌の各種画像と伸展固定肺の比較検討 : 特に高分解能CT像との対比
- 肝血管肉腫の1切除例
- 原発性非小細胞型肺癌における高頻度なVEGFの発現
- ラット肺癌発生に対するErythromycin, Ampicillin, 小柴胡湯の抑制効果
- N-Nitrosobis(2-hydroxypropyl)amine(BHP)誘発ラット肺胞上皮過形成のK-ras遺伝子異常と可逆性 : 前癌病変・組織形態2
- 放射線照射におけるメタリックステントの影響 : ファントムおよび雑犬正常胆管を用いた基礎的研究
- 6. ラットにおけるN-nitrosobis(2-hydroxypropyl)amine(BHP)による肺発癌過程でのKi-ras遺伝子の変異(第60回日本肺癌学会関西支部会)
- 多発性頭蓋外転移巣のみられた悪性髄膜腫
- 504 機能性膵ラ氏島腫瘍の局在診断と外科的治療(第29回日本消化器外科学会総会)
- 482 胆嚢頸部に発生した悪性リンパ腫の1治験例(第28回日本消化器外科学会総会)
- Alterations of the Transforming Growth Factor-β Signaling Pathway in Hepatocellular Carcinomas Induced Endogenously and Exogenously in Rats
- Mutations and Reduced Expression of the Transforming Growth Factor-β Receptor II Gene in Rat Lung A denocarcinomas Induced by N-Nitrosobis-(2-hydroxypropyl)amine
- Elevated Expression of Interleukins in Lung Adenocarcinomas Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats
- Hypomethylation of CpG Sites and c-myc Gene Overexpression in Hepatocellular Carcinomas, but Not Hyperplastic Nodules, Induced by a Choline-deficient L-Amino Acid-defined Diet in Rats
- Increased Telomerase Activities in Human Pancreatic Duct Adenocarcinomas
- 385 肝細胞癌ならびに非癌部肝細胞におけるテロメアDNAの短縮(第47回日本消化器外科学会総会)
- Mutagenic activation of N-nitrosobis(2-oxopropyl)amine by pancreatic juice and assessment of its ductal tumorigenicity following intraductal administration in dogs.
- Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
- Telomerase Activity Correlates with Growth of Transplantable Osteosarcomas in Rats Treated with cis-Diammine Dichloroplatinum or the Angiogenesis Inhibitor AGM-1470
- Comutagenic Effect of Bile Acids with 2-Aminoanthracene, 1,2-Dimethylhydrazine and Pancreas-carcinogenic N-Nitroso Compounds.
- Enhancement of N-nitrosodiethylamine-Initiated Hepatocarcinogenesis Caused by a Colchicine-induced Cell Cycle Disturbance in Partially Hepatectomized Rats.
- Lack of significant tumor induction by endogeneously formed N-nitrosobis(2-hydroxypropyl)amine in rats fed tris(2-hydroxypropyl)-amine and sodium nitrite.
- Effect of cigarette smoke on the mutagenic activation of various carcinogens in hamster.
- A New cytochrome P450 inducer for Ames test.
- 58.多彩な組織亜型を呈した肺腺癌の1剖検例 : 第55回日本肺癌学会関西支部会
- 403 妊娠女性に発症したNeuroblastomaの一例(第38回日本消化器外科学会総会)
- 十二指腸に逸脱した胃腺腫内癌の1例
- 71.多発性小腸転移巣穿孔により死亡した肺扁平上皮癌の一剖検例(第52回日本肺癌学会関西支部会)
- 1.ヒト肺癌におけるGlutathione S-transferase π form(GST-π)の免疫組織化学的検討と細胞診への応用(第52回日本肺癌学会関西支部会)
- 427 ヒト肺癌症例におけるGlutathione S-transferase π form(GST-π)の発現
- 55 N-nitrosobis(2-hydroxypropyl)amine(BHP)によるラット肺腺癌の発生母地に関する研究
- Molecular Aspects during Multi-step Chemical Induced Carcinogenesis in the Lung and Pancreas
- 肝・胆道癌発生に対する寄生虫Opisthorchis viverriniの関与
- 細菌の関与した生体内ニトロソ化反応
- 乳癌,胃癌を併発した膵の solid and cystic tumor の1例
- Possible Involvement of Adaptation Mechanisms in the Achievement of an Ineffective Dose Range for the Carcinogenicity of Genotoxic Carcinogens
- Effects of phenyl N-tert-butyl nitrone and its derivatives on the early phase of hepatocarcinogenesis in rats fed a choline-deficient, L-amino acid-defined diet
- Development of Hepatocellular Adenomas and Carcinomas Associated with Fibrosis in C57BL/6J Male Mice Given a Choline-deficient, L-Amino Acid-defined Diet
- Inhibition of Early-phase Exogenous and Endogenous Liver Carcinogenesis in Transgenic Rats Harboring a Rat Glutathione S-Transferase Placental Form Gene
- Systemic mast cell disease with splenic infarction : A case report
- Promotion of Rat Hepatocarcinogenesis by Dimethylarsinic Acid : Association with Elevated Ornithine Decarboxylase Activity and Formation of 8-Hydroxydeoxyguanosine in the Liver
- Inhibition by Green Tea Extract of Diethylnitrosamine-initiated but Not Choline-deficient, L-Amino Acid-defined Diet-associated Development of Putative Preneo-plastic, Glutathione S-Transferase Placental Form-positive Lesions in Rat Liver
- Increased Telomerase Activity in Hyperplastic Nodules and Hepatocellular Carcinomas Induced by a Choline-deficient L-Amino Acid-defined Diet in Rats
- Dose-dependent Induction of 8-Hydroxyguanine and Preneoplastic Foci in Rat Liver by a Food-derived Carcinogen, 2-Amino-3, 8-dimethylimidazo [4,5-f] quinoxaline, at Low Dose Levels
- Prevention by Methionine of Enhancement of Hepatocarcinogenesis by Coadministration of a Choline-deficient L-Amino Acid-defined Diet and Ethionine in Rats
- 19. AFP 産生食道癌の1例(第41回食道疾患研究会)
- 術後5年以後に再発した胃癌症例の検討
- 早期胃癌症例の臨床病理学的検討
- 25 肝転移胃癌の予後 : 特に肝合併切除の意義について(第14回日本消化器外科学会総会)
- 外科的立場より老年者胃癌と比較した若年者胃癌の特徴
- 肝転移胃癌の予後 : とくに肝合併切除例を中心として
- 噴門部癌の問題点 : 食道浸潤例の切除線決定に対する検討
- 2-Aminoanthracene, 1,2-dimethylhydrazine 及び膵発癌性N-ニトロソ化合物に対する胆汁酸の助変異原性