MEASUREMENT OF UNSCHEDULED DNA SYNTHESIS ON ALKYLATING CARCINOGENS IN RAT INTESTINAL MUCOSAL CELLS FROM DIFFERENT SITES
スポンサーリンク
概要
- 論文の詳細を見る
Unscheduled DNA synthesis (UDS) induced by in vitro exposure to five alkylating carcinogens was measured in the mucosal cells from three different sites of the rat intestine. The yield of UDS by N-methyl-N'-nitro-N-nitrosoguanidine or N-ethyl-N'-nitro-N-nitrosoguanidine or methylazoxymethanol acetate was higher in the cells of colon & rectum than in those of the jejunum or ileum. Conversely, UDS induction by N-methyl-N-nitrosourea or methyl-methanesulphonate was seen at a rather higher level in the cells from the small intestine compared with those from the colon & rectum.
- 日本トキシコロジー学会の論文
- 1984-02-25
著者
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SUGIE Shigeyuki
Department of Oncologic Pathology, Kanazawa Medical University
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TANAKA Takuji
Department of Oncologic Pathology, Kanazawa Medical University
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Mori Hideki
Department of Biological Science, Graduate School of Science, Osaka Prefecture University
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MORI Noriko
Department of Medicine, Shizuoka General Hospital
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Sugie S
Department Of Oncologic Pathology Kanazawa Medical University
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Sugie Shigeyuki
京都大学 農学研究科食品生物科学
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Sugie S
Kanazawa Medical Univ. Ishikawa
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Tanaka Takuji
京都大学 農学研究科食品生物科学
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TAKAHASHI Masayoshi
Department of Pathology, Gifu University School of Medicine
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Tanaka Takuji
Department Of Oncologic Pathology Kanazawa Medical University
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Sugie Shigeyuki
Department Of Oncologic Pathology Kanazawa Medical University
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Mori Hideki
Department Of Anatomy Okayama University Medical School
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OHBAYASHI Futoshi
Department of Pathology, Gifu University School of Medicine
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Mori Noriko
Department Of Cardiology Shizuoka General Hospital The 3rd Department Of Cardiology
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Ohbayashi Futoshi
Department Of Pathology Gifu University School Of Medicine
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Mori Noriko
Department Of Internal Medicine Gifu University School Of Medicine
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Takahashi Masayoshi
Department Of Gastroenterology And Hepatology Toho University Medical Center Omori Hospital
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Tanaka Takuji
Department of Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine
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