Effect of Mirabilitum in Formularization: Change of Prolyl Endopeptidase Inhibitory Activity and of Constituents Using the Preparation Method of Tokaku-joki-to(桃核承気湯, Persia and Rhubarb Combination)
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概要
- 論文の詳細を見る
To clarify the effect of Mirabilitum in formularization, change of prolyl endopeptidase inhibitory activity and of constituents using the preparation method of a Kampo formula Tokaku-joki-to(桃核承気湯, Persia and Rhubarb Combination)was examined by the liquid chromatography-mass spectroscopy(LC-MS)method. Mirabilitum under boiling condition caused qualitative and quantitative change of the constituents through hydrolysis which caused a change of its activity. This was considered to be the main reason the classical Chinese medical book "Shang han lun(傷寒論)" specified that Mirabilitum should be added at a later stage of decoction.
- 公益社団法人日本薬学会の論文
- 2001-05-01
著者
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Kadota Shigetoshi
富山大学和漢医薬学総合研究所 化学応用分野
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Kadota S
Institute Of Natural Medicine University Of Toyama
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Kadota Shigetoshi
インドネシア
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門田 重利
Institute Of Natural Medicine University Of Toyama
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Tezuka Yasuhiro
Institute Of Natural Medicine Univeristy Of Toyama
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Fan Wenzhe
Institute Of National Medicine Toyama Medical And Pharmaceutical University
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Kadota Shigetoshi
Institute Of Natural Medicine Toyama Medical And Pharmaceutical University
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Kalauni S
Institute Of Natural Medicine University Of Toyama
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Kadota S
Toyama Medical And Pharamaceutical Univ. Toyama Jpn
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手塚 康弘
Institute Of Natural Medicine University Of Toyama
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門田 重利
Institute of Natural Medicine, University of Toyama
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