Three New Quassinoids, Ailantinol E, F, and G, from Ailanthus altissima

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概要

• 論文の詳細を見る

• Three new quassinoids, ailantinol E (1), ailantinol F (2), and ailantinol G (3), and related compounds were isolated from Ailanthus altissima grown in Taiwan. Their structures were elucidated from spectral evidence. Each new quassinoid was evaluated for its antitumor promoting effects against Epstein-Barr virus early antigen activation introduced by 12-O-tetradecanoylphorbol-13-acetate in Raji cells. The new quassinoids were found to show potent activity without showing any cytotoxicity. The screening for inhibitors against nitric oxide donor action was also conducted using the new quassinoids and some standard samples.

• 公益社団法人日本薬学会の論文
• 2003-04-01

著者

• 小池 一男

  東邦大・薬

• Okano M

  Kitasato Univ. Sagamihara Jpn

• 大村 三男

  Fruit Tree Research Station

• TAKAYASU Junko

  Department of Molecular Biochemistry, Kyoto Prefectural University of Medicine

• TOKUDA Harukuni

  Department of Molecular Biochemistry, Kyoto Prefectural University of Medicine

• KOIKE Kazuo

  School of Pharmaceutical Sciences, Toho University

• NISHINO Hoyoku

  Department of Biochemistry, Kyoto Prefectural University of Medicine

• Oyama Masayoshi

  Laboratory of Pharmacognosy, Gifu Pharmaceutical University

• Omura M

  Okitsu Branch Fruit Tree Research Station Ministry Of Agriculture Forestry And Fisheries

• Omura Mitsuo

  Faculty Of Pharmacy Meijo University

• Koike Kazuo

  Toho University School Of Pharmaceutical Sciences

• Koike Kazuo

  School Of Pharmaceutical Sciences Toho University

• Nishino H

  Toho University School Of Pharmaceutical Sciences

• Nishino H

  Department Of Biochemistry And Molecular Biology Kyoto Prefectural University Of Medicine

• Nishino Hoyoku

  Department Of Biochemistry And Molecular Biology Graduate School Of Medical Science Kyoto Prefectura

• Aoi Wataru

  Department Of Biochemistry Kyoto Prefecture! University

• Ohtani Mikinobu

  Department Of Urology Instiute Of Clinical Medicine University Of Tsukuba

• TAMURA Sadaaki

  Faculty of Integrated Art and Sciences, Hiroshima University

• FUKAMIYA Narihiko

  Faculty of Integrated Art and Sciences, Hiroshima University

• OKANO Masayoshi

  Faculty of Integrated Art and Sciences, Hiroshima University

• KOYAMA Junko

  Faculty of Pharmaceutical Science, Kobe Pharmaceutical University

• KUCHIDE Masashi

  Department of Biochemistry, Kyoto Prefecture! University

• KUCHIDE Masashi

  Kyoto Prefectural University of Medicine

• TAKAYASU Junko

  Kyoto Prefectural University of Medicine

• TOKUDA Harukuni

  Kyoto Prefectural University of Medicine

• Tokuda Harukuni

  Dep. Of Complementary And Alternative Medicine Clinical R&d Graduate School Of Medical Sci. Kana

• Tokuda Harukuni

  Department Of Biochemistry And Molecular Biology Kyoto Prefectural University Of Medicine

• Koyama J

  Kobe Pharmaceutical University

• Tamura Sadaaki

  Faculty Of Integrated Art And Sciences Hiroshima University

• Onozawa Mizuki

  Cancer Prevenition Division National Cancer Center Research Instiute

• Takayasu Junko

  Department Of Biochemistry And Molecular Biology Graduate School Of Medical Science Kyoto Prefectura

• KUMAKI Kunio

  The Yamagata Prefectural Institute of Public Health

• Tamura S

  Technological Development Laboratories Fujisawa Pharmaceutical Co. Ltd.

• 田村 繁樹

  Technological Development Laboratories Fujisawa Pharmaceutical Co. Ltd.

• Fukamiya N

  Faculty Of Integrated Art And Sciences Hiroshima University

• Ohyama M

  Cancer Prevenition Division National Cancer Center Research Instiute

• Kuchide Masashi

  Department Of Biochemistry Kyoto Prefecture! University

• KOIKE KAZUO

  School of Pharmaceutical Science, Toho University

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