Anti-tuberculosis Activity of Quassinoids
スポンサーリンク
概要
- 論文の詳細を見る
In vitro evaluation of anti-tuberculosis activity was conducted for fifty-six quassinoids isolated in our laboratory from Simaroubaceous plants, Ailanthus altissima (=Aa, 10 compounds), Brucea antidysenterica (=Ba, 16 compounds), Picrasma ailanthoides (=Pa, 14 compounds), and Brucea javanica (=Bj, 16 compounds). Of the compounds tested, shinjulactone K (1), ailanthone (2), shinjudilactone (3), and dehydrobruceantin (4) were the most potent. Although the activities were very low (0-19%), the resulting data provided a picture of structure-activity relationships.
- 公益社団法人日本薬学会の論文
- 1997-09-15
著者
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Lee K‐h
Division Of Medicinal Chemistry And Natural Products School Of Pharmacy University Of North Carolina
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Lee Kuo-hsiung
台湾
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Lee Kuo-hsiung
Natural Products Laboratory School Of Pharmacy University Of North Carolina
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Okano M
Kitasato Univ. Sagamihara Jpn
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Omura M
Okitsu Branch Fruit Tree Research Station Ministry Of Agriculture Forestry And Fisheries
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Lee Kuo-hsiung
Division Of Medicinal Chemistry And Natural Products School Of Pharmacy University Of North Carolina
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Ohtani Mikinobu
Department Of Urology Instiute Of Clinical Medicine University Of Tsukuba
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FUKAMIYA Narihiko
Faculty of Integrated Art and Sciences, Hiroshima University
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FUKAMIYA Narihiko
Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Scien
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TAGAHARA Kiyoshi
Faculty of Pharmaceutical Sciences, Kobe Pharmaceutical University
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OKANO Masayoshi
Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Scien
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RAHMAN Shakila
Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Scien
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Lee K‐h
Univ. North Carolina Nc Usa
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Rahman Shakila
Department Of Interdisciplinary Studies Of Natural Environment Faculty Of Integrated Arts And Scienc
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TAGAHARA Kiyoshi
Kobe Pharmaceutical University
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Fukamiya N
Faculty Of Integrated Art And Sciences Hiroshima University
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Tagahara K
Kobe Pharmaceutical University
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