Antitumor Agents. 168. Dysoxylum cumingianum. IV. The Structures of Cumingianosides G-O, New Triterpene Glucosides with a 14,18-Cycloapotirucallane-Type Skeleton from Dysoxylum cumingianum, and Their Cytotoxicity against Human Cancer Cell Lines
スポンサーリンク
概要
- 論文の詳細を見る
Nine new triterpene glucosides, named cumingianosides G-O (4-7,9,12-15), containing a 14,18-cycloapotirucallane-type skeleton were isolated from a cytotoxic fraction of the leaves of Dysoxylum cumingianum. The structures of the new compounds were established on the basis of chemical and spectral examinations. Evaluation of the cytotoxic activity of cumingianosides G-O showed that cumingianoside M exhibited significant (<4 μM) cytotoxicity, especially against leukemia and melanoma cell lines.
- 公益社団法人日本薬学会の論文
- 1997-01-15
著者
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柏田 良樹
徳島大学薬学部
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Lee K‐h
Division Of Medicinal Chemistry And Natural Products School Of Pharmacy University Of North Carolina
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Lee K‐h
Kyoto Pharmaceutical Univ. Kyoto Jpn
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Lee Kuo-hsiung
Natural Products Research Laboratories School Of Pharmacy University Of North Carolina
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Lee Kuo-hsiung
Natural Products Laboratory Division Of Medicinal Chemistry And Natural Products School Of Pharmacy
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FUJIOKA Toshihiro
Faculty of Pharmaceutical Sciences, Fukuoka University
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CHEN Ih-Sheng
School of Pharmacy, Kaohsiung Medical College
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Chen I‐s
Kaohsiung Medical Univ. Kaohsiung Twn
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Chen Ih-sheng
Natural Products Research Center Kaoshiung Medical College
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MIHASHI Kunihide
Faculty of Pharmaceutical Sciences, Fukuoka University
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柏田 良樹
徳島大院薬
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柏田 良樹
徳島大学大学院ヘルスバイオサイエンス研究部(薬学系)
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Sakurai Akio
Faculty Of Pharmaceutical Sciences Fukuoka University
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柏田 良樹
Faculty Of Pharmaceutical Sciences Kyushu Unversity
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Kashiwada Y
Niigata Univ. Pharmacy And Applied Life Sci. Niigata Jpn
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Kashiwada Yoshiki
Niigata College Of Pharmacy
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Lee K‐h
Univ. North Carolina Nc Usa
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Fujioka T
Faculty Of Pharmaceutical Sciences Fukuoka University
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Fujioka Toshihiro
Faculty Of Pharmaceutical Sciences Fukuoka University
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Mihashi Kunihide
Faculty Of Pharmaceutical Sciences Fukuoka University
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