Cytotoxic and Anti-HIV Principles from the Rhizomes of Begonia nantoensis

スポンサーリンク

概要

• 論文の詳細を見る

• Three new compounds: begonanline (1), nantoamide (2) and methyl (S)-glycerate (3) as well as forty-four known compounds have been isolated and characterized from the rhizomes of Begonia nantoensis. The structures of these compounds were determined by spectral analyses and/or X-ray crystallography. Among them, cucurbitacin B (4), dihydrocucurbitacin B (5), cucurbitacin E (6), dihydrocucurbitacin E (7), cucurbitacin I (8), and (-)-auranamide (9) showed cytotoxicity against four human cancer cell lines. 3β,22α-Dihydroxyolean-12-en-29-oic acid (10), indole-3-carboxylic acid (11), 5,7-dihydroxychromone (12), and (-)-catechin (13) demonstrated significant activity against HIV replication in H9 lymphocyte cells.

• 社団法人日本薬学会の論文
• 2004-03-01

著者

• Lee K‐h

  Division Of Medicinal Chemistry And Natural Products School Of Pharmacy University Of North Carolina

• Lee Kuo-hsiung

  Natural Products Research Laboratories School Of Pharmacy University Of North Carolina

• Lee Kuo-hsiung

  Natural Products Laboratory Division Of Medicinal Chemistry And Natural Products School Of Pharmacy

• Lee Kuo-hsiung

  台湾

• Lee Kuo-hsiung

  Natural Products Laboratory School Of Pharmacy University Of North Carolina

• Wu T‐s

  National Cheng Kung Univ. Tainan Twn

• Lee K‐h

  Natural Products Laboratory School Of Pharmacy University Of North Carolina

• Kuoh C‐s

  Department Fo Biology National Cheng Kung University

• WU Tian-Shung

  Department of Chemistry, National Cheng-Kong University

• Wu Tian-shung

  Department Of Chemistry National Cheng Kung University

• Wu Tian-shung

  Dep. Of Chemistry National Cheng Kung Univ.

• WU Pei-Lin

  Department of Chemistry, National Cheng Kung University

• LIN Fu-Wen

  Department of Chemistry, National Cheng Kung University

• KUOH Chang-Sheng

  Department fo Biology, National Cheng Kung University

• LEE Shiow-Ju

  Division of Biotechnology and Pharmaceutical Research, National Health Research institutes

• Wu Tian-shung

  Department Of Applied Chemistry Providence College Of Arts And Science

• Wu P‐l

  National Cheng Kung Univ. Tainan Twn

• Wu Pei-lin

  Department Of Chemistry National Cheng Kung University

• Lee K‐h

  Univ. North Carolina Nc Usa

• Lin F‐w

  Department Of Chemistry National Cheng Kung University

• Lin Fu-wen

  Department Of Chemistry National Cheng Kung University

• Lee Shiow-ju

  Division Of Biotechnology And Pharmaceutical Research National Health Research Institutes

関連論文

• Constituents of Rosaceous Plants. I. Structures of New Triterpenoids from Cowania mexicana
• 65 Amorpha fruticosaより得られる新規ロテノイドの化学的研究(ポスター発表の部)
• PA154 BRYOPHYLLIN-A and -B, NOVEL POTENT CYTOTOXIC BUFADIENOLIDE ORTHOACETATES FROM BRYOPHYLLUM PINNATUM
• Anti-inflammatory Principles from the Stem and Root Barks of Citrus medica
• FISSOLDHIMINE, A NOVEL SKELETON ALKALOID FROM FISSISTIGMA OLDHAMII
• Cytotoxic and Anti-HIV Principles from the Rhizomes of Begonia nantoensis
• A New Phytoecdysteroid from Ajuga taiwanensis
• Constituents from the Stem and Root of Aristolochia kaempferi
• The Constituents of the Root and Stem of Aristolochia cucurbitifolia Hayata and Their Biological Activity
• The Constituents of the Root and Stem of Aristolochia heterophylla Hemsl
• The Constituents of the Leaves of Aristolochia heterophylla HEMSL.
• Constituents of the Fresh Leaves of Aristolochia cucurbitifolia
• Constituents of the Leaves of Aristolochia kaempferi
• Denitroaristolochic Acid from the Leaves of Aristolochia cucurbitifolia HAYATA
• Naphthoquinone Esters from the Root of Rhinacanthus nasutus
• ARISTOLIDE-A AND -B, TWO NOVEL DIHYDROPHENANTHRENE-LACTONES FROM ARISTOLOCHIA HETEROPHYLLA HEMSL
• Plant-derived natural product research aimed at new drug discovery
• 5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix
• ELECANACIN, A NOVEL NEW NAPHTHOQUINONE FROM THE BULB OF ELEUTHERINE AMERICANA
• Synthesis and Antiplatelet, Antiinflammatory and Antiallergic Activities of 2,3-Disubstituted 1,4-Naphthoquinones
• Constituents from the Stems of Hibiscus taiwanensis
• STRUCTURE AND STEREOCHEMISTRY OF BRYOPHYLLIN-A, A NOVEL POTENT CYTOTOXIC BUFADIENOLIDE ORTHOACETATE FROM ___- ___-
• Structural Elucidation and Chemical Conversion of Amorphispironone, a Novel Spironone form Amorpha fruticosa, to Rotenoids
• Glycosides from Paeonia suffruticosa
• Constituents of the Pollen of Crocus sativus L. and Their Tyrosinase Inhibitory Activity
• Anthraquinones from Ophiorrhiza hayatana OHWI
• Constituents of Leaves of Phellodendron japonicum MAXIM. and Their Antioxidant Activity
• New Neolignans from Spiraea formosana
• Flavonoids from Andrographis viscosula
• Cytotoxic Anthraquinones from the Stems of Rubia wallichiana DECNE
• New Diterpenoid Alkaloid from Spiraea formosana
• PA149 STRUCTURE AND STEREOCHEMISTRY OF THALICSILINE, A NEW ANTIINFLAMMATORY C_-DITERPENOID ALKALOID FROM THALICTRUM SESSILE
• PeMADS6, a GLOBOSA/PISTILLATA-like Gene in Phalaenopsis equestris Involved in Petaloid Formation, and Correlated with Flower Longevity and Ovary Development
• New Pavine N-Oxide Alkaloids from ths Stem Bark of Cryptocarya chinensis HEMSL.
• Conversion of Quassinoids for Enhancement of Inhibitory Effect against Epstein-Barr Virus Early Antigen Activation. Introduction of Lipophilic Side Chain and Esterification of Diosphenol
• Three New Quassinoid Derivatives and Related Compounds as Antitumor Promoters from Brucea javanica
• Anti-tuberculosis Activity of Quassinoids
• Inhibitory Effects of Quassinoid Derivatives on Epstein-Barr Virus Early Antigen Activation
• Two New Quassinoids, Ailantinols C and D, from Ailanthus Altissima
• Antifeedant and Insecticidal Activity of Quassinoids against the Diamondback Moth (Plutella xylostella) and Structure-Activity Relationships
• Two New Dimeric Acridone Alkaloids from Glycosmis citrifolia
• Chemical Constituents of Glycosmis citrifolia (WILLD.) LINDL.Structures of Four New Acridones and Three New Quinolone Alkaloids
• Synthesis and Anti-HIV Activity of 3-Alkylamido-3-deoxy-betulinic Acid Derivatives
• Antitumor Agents. 169. Dysoxylum cumingianum. V. Cumingianosides P and Q, New Cytotoxic Triterpene Glucosides with an Apotirucallane-Type Skeleton from Dysoxylum cumingianum
• Antitumor Agents. 168. Dysoxylum cumingianum. IV. The Structures of Cumingianosides G-O, New Triterpene Glucosides with a 14,18-Cycloapotirucallane-Type Skeleton from Dysoxylum cumingianum, and Their Cytotoxicity against Human Cancer Cell Lines
• Influence of Calcining Temperature on CuO-Modified (Ba_Sr_)(Ti_Zr_)O_3 Ceramics
• Constitutents of the Roots of Rubia yunnanensis
• Alkaloids from the Leaves of Cryptocarya chinensis HEMSL.
• The Bakkenolides from the Root of Petasites formosanus and Their Cytotoxicity
• pH Dependence of Interparticle Coupling for Gold Nanoparticle Assemblies Formation : Electrostatic Attraction and Hydrogen Bonding
• Constituents from the Leaves of Phellodendron amurense and Their Antioxidant Activity
• Cytotoxic Arylnaphthalene Lignans from Phyllanthus oligospermus
• Quantitative Analysis of Camptothecin Derivatives in Nothapodytes foetida Using ^1H-NMR Method
• Acricone Alkaloids from the Root Bark of Severinia buxifolia in Hainan
• Four DEF-Like MADS Box Genes Displayed Distinct Floral Morphogenetic Roles in Phalaenopsis Orchid
• A Novel Phenylpropenoyl Sulfonic Acid and a New Chlorophyll from the Leaves of Petasites formosanus KITAMURA
• Lactonic Carbazole Alkaloids from the Root Bark of Clausena excavata
• Simultaneous analysis of nine components in patch preparations of Ru-Yi-Jin-Huang-San by high-performance liquid chromatography
• Dyscusins A—C, Three New Steroids from the Leaves of Dysoxylum cumingianum
• PA148 THE CONSTITUENTS OF MURRAYA PANICULATA VAR. OMPHALOCARPA
• The Constituents and Their Bioactivities of Houttuynia cordata
• An Efficient Synthesis of a Potent Anti-inflammatory Agent, Viscolin, and Its Inducible Nitric Oxide Synthase Inhibitory Activity
• Preparation of a Series of Novel Bichalcones Linked with a 1,4-Dimethylenepiperazine Moiety and Examination of Their Cytotoxicity
• Ca2+-Channel Blockade in Rat Thoracic Aorta by Protopine Isolated from Corydalis Tubers.

もっと見る 閉じる

スポンサーリンク