The Bakkenolides from the Root of Petasites formosanus and Their Cytotoxicity

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概要

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• Thirty-two new bakkenolides, bakkenolides-Db (1)--Dh (7), -Fa (8), -Fb (9), -I (10)--M (14), -Na (15), -Nb (16), -O (17)--T (22), -Ua (23), -Ub (24), -V (25)--X (27), -Ya (28), -Yb (29), -Za (30), -Zb (31) and -III (32), from the roots of Petasites formosanus together with thirty known compounds were isolated. The structures were characterized by spectral analysis. The locations, C-1 and/or C-9 bakkenolide skeleton, of the substituents, such as acetoxy, isobutyroyloxy and isovaleroyloxy groups, can be determined by the chemical shifts of their signals and the H-1 and/H-9 in the ^1H-NMR spectra. The cytotoxicity was also discussed.

• 公益社団法人日本薬学会の論文
• 1999-03-15

著者

• Wu T‐s

  National Cheng Kung Univ. Tainan Twn

• WU Tian-Shung

  Department of Chemistry, National Cheng-Kong University

• Wu Tian-shung

  Department Of Chemistry National Cheng Kung University

• Wu Tian-shung

  Dep. Of Chemistry National Cheng Kung Univ.

• WU Pei-Lin

  Department of Chemistry, National Cheng Kung University

• Wu Tian-shung

  Department Of Applied Chemistry Providence College Of Arts And Science

• Wu P‐l

  National Cheng Kung Univ. Tainan Twn

• LI Chia-Ying

  Department of Chemistry, National Cheng Kung University

• Li Chia-ying

  Department Of Chemistry National Cheng Kung University

• Shi Li-Shian

  Department of Chemistry, National Cheng Kung University

• Wu Pei-lin

  Department Of Chemistry National Cheng Kung University

• Shi Li-shian

  Department Of Chemistry National Cheng Kung University

• LIOU Meei-Jen

  Department of Chemistry, National Cheng Kung University

• KAO Mang-San

  Department of Chemistry, National Cheng Kung University

• LIN Ful-Wen

  Department of Chemistry, National Cheng Kung University

• Lin Ful-wen

  Department Of Chemistry National Cheng Kung University

• Kao Mang-san

  Department Of Chemistry National Cheng Kung University

• Liou Meei-jen

  Department Of Chemistry National Cheng Kung University:republic Of China And Department Of Applied C

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