Formation of Trisulfide from Thiosulfonate with Amine Catalyst

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概要

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• Benzyl p-toluenethiosulfonate was found to form dibenzyltrisulfide with amine catalyst in the presence of water. On the other hand, α-benzylmercaptobenzyl p-toluenethiosulfonate was formed with amine catalyst in the presence of sulfur in 15% yield, without any dibenzyltrisulfide was obtained. The treatment with sodium hydroxide solution also gave benzylmercaptobenzyl p-toluenethiosulfonate in 49% yield. The mechanism of these reaction was presumed.

• 公益社団法人日本薬学会の論文
• 1971-11-25

著者

• 古川 潮

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 林 清五郎

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 藤野 洋子

  Institute for Medical and Dental Engineering, Tokyo Medical and Dental University

• 岡部 洋

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 藤野 洋子

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 藤野 洋子

  Institute For Medical And Dental Engineering Tokyo Medical And Dental University

• 林清 五郎

  Faculty Of Pharmaceutical Sciences Kumamoto University

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