A One-Pot Synthesis of β-Lactams by the Reaction of β-Haloacyl Chlorides with α-Amino Acids

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概要

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• A one-pot synthesis of β-lactams (4) was successfully achieved by the reaction of β-haloacyl chlorides (1) with α-amino acids (2) in aqueous 5% sodium hydroxide solution in the absence of phase transfer catalyst in yields of 43-91%.

• 公益社団法人日本薬学会の論文
• 1982-05-25

著者

• 古川 潮

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 野口 芳秀

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 大川 原正

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 松田 隆至

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 野口 芳秀

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 松田 隆至

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 大川 原正

  Faculty Of Pharmaceutical Sciences Kumamoto University

関連論文

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