The Reaction of 1,3-Disubstituted Thioureas with α, ω-Dibromoacyl Chlorides and the Formation of Spiro Compounds
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概要
- 論文の詳細を見る
5-Bromoalkyl-2-iminothiazolidin-4-ones (3) were readily synthesized from 1,3-disubstituted thioureas (1) and α, ω-dibromoacyl chlorides (2) in 5% NaOH-CH_2Cl_2. Compounds 3 were converted to the corresponding spiro compounds 9 under phase-transfer conditions or with sodium ethoxide.
- 公益社団法人日本薬学会の論文
- 1986-01-25
著者
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古川 潮
Faculty Of Pharmaceutical Sciences Kumamoto University
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山崎 哲郎
Bristol-myers Squibb Research Institute Ltd. Tokyo Research Center
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大川原 正
Faculty of Pharmaceutical Sciences, Kumamoto University
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山崎 哲郎
Faculty of Pharmaceutical Sciences, Kumamoto University
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中山 研太郎
Faculty of Pharmaceutical Sciences, Kumamoto University
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大川原 正
Faculty Of Pharmaceutical Sciences Kumamoto University
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中山 研太郎
Faculty Of Pharmaceutical Sciences Kumamoto University
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