Reaction of Biguanides and Related Compounds. XIV. Cyclization of Amidinothioureas with Some Carbonyl Compounds

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概要

• 論文の詳細を見る

• The reaction of amidinothioureas (II) with aldehydes or acetone and with methyl chloroacetate were found to form 6-amino-4-mercapto-2-substituted 1,2-dihydro-1,3,5-triazines (III) and 2-guanidylidene-4-thiazolidones (V), respectively.

• 公益社団法人日本薬学会の論文
• 1978-01-25

著者

• 古川 潮

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 大川原 正

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 野口 芳秀

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 宮崎 隆一

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 野口 芳秀

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 大川原 正

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 宮崎 隆一

  Faculty Of Pharmaceutical Sciences Kumamoto University

関連論文

• Studies on Antitumor Substances. XIV. Syntheses of Bisquarternary Ammonium Salts and the Reaction with Nucleophiles
• Studies on Antitumor Substances. VII. Reaction of N-Amidino-O-alkylisourea with Some Carboxylic Esters
• The Mechanism for the Reaction of Biguanides with Diethyl Oxalate
• Syntheses of New Pyrazoline Derivatives
• Studies on Antitumor Substances. VI. Chemical Behaviors of Thiosulfonates, Disulfonyl Sulfides, and Related Compounds.
• Studies on Antitumor Substances. V. Reaction of Thiosulfonates with Active Methylene Compounds.
• Facile Reduction of Intermediates from Carboxylic Acids and 6-Nitro-1-(2-nitrophenylsulfonyloxy)benzotriazole with Sodium Borohydride to Alcohols
• The Reaction of 1,3-Disubstituted Thioureas with α, ω-Dibromoacyl Chlorides and the Formation of Spiro Compounds
• Reactions of p-Toluenesulfinic Acid with Dialkoxy or Diamino Sulfides and Disulfides
• A Facile Preparation of 4-Thiazolone Derivatives from Thioamides and Various Haloacyl Halides in a Biphase System
• Facile Preparations of 1,4-(Diphenylmethyleneamino) piperazine-2,5-diones and N-Phenylmethyleneamino-β, γ, and δ-lactams from Benzylidene Hydrazines and α, β, γ, and δ-Haloacyl Halides
• Reaction of Biguanides and Related Compounds. XV. Cyclizations of Arylbiguanides and 2-Guanidinobenzimidazole with Bifunctional Unsaturated Dicarboxylates to s-Triazines and Imidazolines
• Behavior of Sulfinic Acid toward N-Chloramines and Related Compounds
• Facile Formation of 1,3-Disubstituted 2,3,5,6-Tetrahydro-2-thioxopyrimidin-4 (1H)-ones and 2-N, 3-Disubstituted 2,3,5,6-Tetrahyro-2-imino-1,3-thiazin-4-ones from Thioureas and β-Haloacyl Halides
• Convenient One-pot Syntheses of Sulfinates, Sulfinamides, and Thiosulfinates by Sulfinylation with p-Toluenesulfinic Acid and Activating Reagents
• A One-Pot Synthesis of β-Lactams by the Reaction of β-Haloacyl Chlorides with α-Amino Acids
• Convenient Syntheses of Cyclic Carboxamides from α, β, γ, δ and ε-Halocarboxamides under Phase Transfer Conditions
• Direct Conversion of Sulfinic Acid to Sulfonic Acid Derivatives
• Thermal Dimerization of Sulfinyl Compounds
• Novel One-step Preparation of Sulfinic Acid Derivatives from Sulfinic Acid
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• Asymmetric Syntheses of β-Amino Acids by the Reduction of Enamines
• Reaction of Epoxides. VI. Reaction of 2,3-Epoxypropyl Aryl Ether with Ethyl-N-phenylformimidate and N, N'-Diphenylformamidine
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• Asymmetric Syntheses of β-Amino Acids by the Addition of Chiral Amines to C=C Double Bonds
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• Conversion of Bis (β-carbamoylethyl) Disulfides into Bis (β-carbamoylethyl) Trisulfides
• Reaction of Biguanides and Related Compounds. XII. Condensations of Arylbiguanides and Amidinoisoureas with Isatins
• Pyrazolines and Oxazolines. Reaction of Arylcarbonylethylthiosulfates with Hydrazines and Hydroxylamines
• Reaction of Epoxides. V. 1,3-Dipolar Cycloaddition Reaction of Epoxides with Carbon-Nitrogen Double Bond Compounds
• Reaction of Biguanides and Related Compounds. X. Formation of s-Triazinethiones by the Condensation of Arylbiguanides with 2,3-Trithiocarbonates
• Thiation of Enamine of Cyclohexanone with Arensulfenamides
• Reaction of Biguanides and Related Compounds. IX. Condensation of N-Amidino-O-alkylisourea and 1-Substituted 3-Amidino-2-thiourea with Benzil
• Reaction of Biguanides and Related Compounds. VIII. The Condensation of Arylbiguanides and N-Amidino-O-alkylisoureas with Diketene and Ethyl Acetoacetate
• The Reaction of Benzyl Phenylmethanethiosulfinate with Amines
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• Criss-cross Cycloaddition of Epoxides to Aromatic Aldazines
• Arylthiation of Cyclohexanone Morpholine Enamine with Aryl Benzenethiosulfonates
• A Convenient Synthesis of Pyrazolines from β-Carbonylethylthiosulfates
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• Mechanism for the Reaction of Sodium Benzylthiosulfate with Morpholine
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• Reactions of Epoxides. I. Synthesis of Trithiocarbonate by the Reaction of Epoxide with Alkali Xanthate
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• Formation of Trisulfide from Thiosulfonate with Amine Catalyst
• Reaction of Disulfide and Trisulfide with N-Chlorocarboxamide
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• Reaction of Biguanides and Related Compounds. I. Reaction of Biguanides with β-Diketone
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• Reaction of 1-Arylbiguanide with Some Carboxylic Esters.
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