Reaction of Biguanides and Related Compounds. XIII. Benzilic Acid Rearrangement. The Reactions of 1,2-Cyclohexanedione and 9,10-Phenanthrenequinone with Arylbiguanides and N-Amidino-0-alkylisoureas
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概要
- 論文の詳細を見る
Benzilic acid rearrangements of 1,2-cyclohexanedione (I) and 9,10-phenanthrenequinone (II) are described : The base-catalysed condensation of I with arylbiguanides (III) and with N-amidino-O-alkylisoureas (IV) gave 2-arylguanidylidene-4-oxo-1,3-diazaspiro [4. 4] nonanes (V) and 2-alkoxyamidinylidene-4-oxo-1,3-diazaspiro [4. 4] nonanes (X) respectively. Analogously, the reaction of II with III and with IV afforded 2-arylguanidylidene-5-fluorenylidene-4-oxoimidazolidines (XI) and 2-alkoxyamidinylidene-5-fluorenylidene-4-oxoimidazolidines (XII) respectively.
- 公益社団法人日本薬学会の論文
- 1975-03-25
著者
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古川 潮
Faculty Of Pharmaceutical Sciences Kumamoto University
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林 清五郎
Faculty Of Pharmaceutical Sciences Kumamoto University
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吉田 孝利
Faculty of Pharmaceutical Sciences, Kumamoto University
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林清 五郎
Faculty Of Pharmaceutical Sciences Kumamoto University
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吉田 孝利
Research Institute, Daiichi Seiyaku Co., Ltd.
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吉田 孝利
Research Institute Daiichi Seiyaku Co. Ltd.
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