Influence of Quinone Derivatives on Insulin, Glucagon, and Insulinase. IV. Interaction of Insulin with Quinone.
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概要
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The binding of insulin with quinones and its derivatives was quantitatively measured by chromatography on dextran gel column and it was found that the rate of binding increased with increasing concentration of free quinones in the range of 0.1 to 1 mM of quinones. The binding of quinones with insulin was also studied by using sedimentation, electrophoretic, and paper electrophoretic analysis. From these results, it was assumed that quinone derivatives might bind to insulin, produce some change in molecular form of insulin, and promote the association of insulin molecule.
- 公益社団法人日本薬学会の論文
- 1963-06-25
著者
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林 清五郎
Faculty Of Pharmaceutical Sciences Kumamoto University
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伊藤 四十二
Faculty of Pharmaceutical Sciences, University of Tokyo
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植木 寛
Faculty Of Pharmaceutical Sciences Kumamoto University
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林清 五郎
Faculty Of Pharmaceutical Sciences Kumamoto University
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伊藤 四十二
東京大学薬学部
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