Reaction of Biguanides and Related Compounds. XII. Condensations of Arylbiguanides and Amidinoisoureas with Isatins

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概要

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• The reactions of arylbiguanides with isatin and with 1-methylisatin gave 2-oxo-3-arylbiguanidylidene-indoles and 4-amino-6-arylamino-2-(1'-methyl-2'-oxo-3'-indolidene)-1,2-dihydro-s-triazines, respectively. Analogously, N-amidino-O-alkylisoureas reacted with isatin and 1-methylisatin to afford 2-oxo-3-alkoxyamidinoamidinylidene-indoles and 4-amino-6-alkoxy-2-(1'-methyl-2'-oxo-3'-indolidene)-1,2-dihydro-s-triazines, respectively. The structures of these compounds were discussed.

• 公益社団法人日本薬学会の論文
• 1974-12-25

著者

• 古川 潮

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 林 清五郎

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 吉田 孝利

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 林清 五郎

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 吉田 孝利

  Research Institute, Daiichi Seiyaku Co., Ltd.

• 吉田 孝利

  Research Institute Daiichi Seiyaku Co. Ltd.

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