Convenient One-pot Syntheses of Sulfinates, Sulfinamides, and Thiosulfinates by Sulfinylation with p-Toluenesulfinic Acid and Activating Reagents

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概要

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• One-pot syntheses of sulfinates, sulfinamides, and thiosulfinates by O-, N-, and S-sulfinylations of alcohols, amines, and thiols with p-toluenesulfinic acid in the presence of various activating reagents, phenyl phosphorodichloridate (1), diphenyl phosphoro-chloridate (2), triphenylphosphine N-chlorosuccinimide (NCS) (3), and 3-(phthalimidoxy)-1,2-benzoisothiazole 1,1-dioxide (4), were investigated. All of these reagents were reasonably effective for O-and S-sulfinylation, but ineffective for N-sulfinylation. Among them, the reagents 1 and 2 were slightly more efficient than the others.

• 公益社団法人日本薬学会の論文
• 1982-05-25

著者

• 古川 潮

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 野口 芳秀

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 磯田 匡宣

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 黒木 研吉

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 野口 芳秀

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 黒木 研吉

  Faculty Of Pharmaceutical Sciences Kumamoto University

• 磯田 匡宣

  Faculty Of Pharmaceutical Sciences Kumamoto University

関連論文

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